Catalog No.
PHD39301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAB5A (Asp136-Asn215).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ras-related protein Rab-5A,RAB5A,RAB5
Purification
Purified by antigen affinity column.
Accession
P20339
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
CTRP7 as a molecular biomarker associating with responsiveness to pulmonary vasodilators: insights from human and animal studies in pulmonary arterial hypertension., PMID:40504501
The mechanisms of HER2 targeted ADCs are dependent on Rab GTPases., PMID:40297622
A trafficking regulatory subnetwork governs αVβ6 integrin-HER2 cross-talk to control breast cancer invasion and drug resistance., PMID:39630893
CD2AP is Co-Expressed with Tropomyosin-Related Kinase A and Ras-Related Protein Rab-5A in Cholinergic Neurons of the Murine Basal Forebrain., PMID:39211110
The effect of drug loading and multiple administration on the protein corona formation and brain delivery property of PEG-PLA nanoparticles., PMID:35847504
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer., PMID:34741021
Direct interaction between Rab5a and Rab4a enhanced epidermal growth factor-stimulated proliferation of gastric cancer cells., PMID:34721780
Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase., PMID:33194812
Programmed death-ligand 1 monoclonal antibody-linked immunoliposomes for synergistic efficacy of miR-130a and oxaliplatin in gastric cancers., PMID:31290727
Association of an IRF3 putative functional uORF variant with resistance to Brucella infection: A candidate gene based analysis of InDel polymorphisms in goats., PMID:30477986
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase., PMID:29127256
Modifiers of prion protein biogenesis and recycling identified by a highly parallel endocytosis kinetics assay., PMID:28341739
Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells., PMID:27110488
The Rab5A gene of marine fish, large yellow croaker (Larimichthys crocea), and its response to the infection of Cryptocaryon irritans., PMID:27108380
Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytes., PMID:24876181
Identification of an immune-regulated phagosomal Rab cascade in macrophages., PMID:24569883
Endocytosis of HERG is clathrin-independent and involves arf6., PMID:24392021
Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella-containing vacuoles from macrophages., PMID:24373249
Internalization of adhesion junction proteins and their association with recycling endosome marker proteins in rat seminiferous epithelium., PMID:22157319
Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway., PMID:21849022
Segmental and subcellular distribution of CFTR in the kidney., PMID:21594792
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1., PMID:21378754
RNA interference and single particle tracking analysis of hepatitis C virus endocytosis., PMID:20041214
Endothelin-converting enzyme-1 degrades internalized somatostatin-14., PMID:18276747
Phagocytosis-induced apoptosis of macrophages is linked to uptake, killing and degradation of bacteria., PMID:18085665
Agonist-induced endocytosis of rat somatostatin receptor 1., PMID:17170097
Expression and subcellular localization of Spred proteins in mouse and human tissues., PMID:15580519
Multiple regions contribute to membrane targeting of Rab GTPases., PMID:15561774
The role of alpha(5)beta(1)-integrin in the IGF-I-induced migration of extravillous trophoblast cells during the process of implantation., PMID:14742693
Apoptosis by Cd2+ or CdMT in proximal tubule cells: different uptake routes and permissive role of endo/lysosomal CdMT uptake., PMID:12890648
Co-localization of rab4 with endocytosis-related proteins in the rat parotid glands., PMID:12703553
Agonist-induced endocytosis of lysophosphatidic acid-coupled LPA1/EDG-2 receptors via a dynamin2- and Rab5-dependent pathway., PMID:12668728
Dynamin and Rab5a-dependent trafficking and signaling of the neurokinin 1 receptor., PMID:11306580
Colocalization of Fc gamma RI-targeted antigen with class I MHC: implications for antigen processing., PMID:11160307
Direct interaction of EEA1 with Rab5b., PMID:10491193
[Transcytosis of immunoglobulin IgG]., PMID:9990196
Identification of Rab3-, Rab5a- and synaptobrevin II-like proteins in a preparation of rat kidney vesicles containing the vasopressin-regulated water channel., PMID:7540151
Mapping of Ras-related GTP-binding proteins by GTP overlay following two-dimensional gel electrophoresis., PMID:8058727
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis., PMID:8043272
Rab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cells., PMID:8197185
For research use only. Not for human or drug use.
