Catalog No.
PHD37701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human KLK2 (Pro19-Pro261).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Kallikrein-2,Tissue kallikrein-2,KLK2,hGK-1,Glandular kallikrein-1
Purification
Purified by antigen affinity column.
Accession
P20151
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Pasritamig, a First-in-Class, Bispecific T-Cell Engager Targeting Human Kallikrein 2, in Metastatic Castration-Resistant Prostate Cancer: A Phase I Study., PMID:40450573
Developmental Therapeutics in Metastatic Prostate Cancer: New Targets and New Strategies., PMID:39272956
A Phase 0 Study to Assess the Biodistribution and Pharmacokinetics of a Radiolabeled Antibody Targeting Human Kallikrein 2 in Participants with Metastatic Castration-Resistant Prostate Cancer., PMID:38782459
Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2., PMID:38396898
Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy., PMID:32532924
Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies ERG as the strongest independent predictor of recurrence., PMID:31741711
Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer., PMID:29691406
Preclinical imaging of kallikrein-related peptidase 2 (hK2) in prostate cancer with a (111)In-radiolabelled monoclonal antibody, 11B6., PMID:26116115
Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome., PMID:25649018
Tickling stimulation causes the up-regulation of the kallikrein family in the submandibular gland of the rat., PMID:22982067
Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies., PMID:20615888
Immunoreactivity of recombinant human glandular kallikrein using monoclonal antibodies raised against prostate-specific antigen., PMID:9140120
For research use only. Not for human or drug use.
