Catalog No.
PHD33301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HK1 (Phe80-Met215).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Hexokinase type I,Hexokinase-1,HK1,Brain form hexokinase,Hexokinase-A,HK I
Purification
Purified by antigen affinity column.
Accession
P19367
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth., PMID:40132583
FOXA1 enhances antitumor immunity via repressing interferon-induced PD-L1 expression in nasopharyngeal carcinoma., PMID:39542656
Clinical Utility of Donor-Derived Cell-Free DNA in Heart Transplant Recipients With Multi-Organ Transplants., PMID:39422086
Targeting SRSF10 might inhibit M2 macrophage polarization and potentiate anti-PD-1 therapy in hepatocellular carcinoma., PMID:39223929
Serum autoantibodies against hexokinase 1 manifest secondary to diabetic macular edema onset., PMID:38821414
Human neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head., PMID:38802413
Mucosal recombinant BCG vaccine induces lung-resident memory macrophages and enhances trained immunity via mTORC2/HK1-mediated metabolic rewiring., PMID:38042489
Allosteric Neutralization by Human H7N9 Antibodies., PMID:37986867
Preclinical evaluation of the VEGF/Ang2 bispecific nanobody BI 836880 in nasopharyngeal carcinoma models., PMID:37572231
Detection of anti-kelch-like 12 and anti-hexokinase 1 antibodies in primary biliary cholangitis patients in China., PMID:33307711
Anti-Aβ Antibody Aducanumab Regulates the Proteome of Senile Plaques and Closely Surrounding Tissue in a Transgenic Mouse Model of Alzheimer's Disease., PMID:33252074
Correction: Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression., PMID:32820250
Novel Anti-Hexokinase 1 Antibodies Are Associated With Poor Prognosis in Patients With Primary Biliary Cholangitis., PMID:32467507
Glycolytic competence in gastric adenocarcinomas negatively impacts survival outcomes of patients treated with salvage paclitaxel-ramucirumab., PMID:32372141
Hemokinin-1 Gene Expression Is Upregulated in Trigeminal Ganglia in an Inflammatory Orofacial Pain Model: Potential Role in Peripheral Sensitization., PMID:32331300
Evaluation of a novel extended automated particle-based multi-analyte assay for the detection of autoantibodies in the diagnosis of primary biliary cholangitis., PMID:32286240
The Prevalence of Anti-Hexokinase-1 and Anti-Kelch-Like 12 Peptide Antibodies in Patients With Primary Biliary Cholangitis Is Similar in Europe and North America: A Large International, Multi-Center Study., PMID:31001269
Improvement Efficacy of Influenza Nanovaccine in Combination with Hemokinin-1 Molecular Adjuvant., PMID:30555652
Evaluation of classical and novel autoantibodies for the diagnosis of Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome (PBC-AIH OS)., PMID:29554146
Distribution of hemokinin-1 in the rat trigeminal ganglion and trigeminal sensory nuclear complex., PMID:28301818
Identification of novel autoantigens via mass spectroscopy-based antibody-mediated identification of autoantigens (MS-AMIDA) using immune thrombocytopenic purpura (ITP) as a model disease., PMID:28137667
Changes in the disposition of substance P in the rostral ventromedial medulla after inflammatory injury in the rat., PMID:26762802
High 18F-FDG uptake in PMAH correlated with normal expression of Glut1, HK1, HK2, and HK3., PMID:25766729
Anti-kelch-like 12 and anti-hexokinase 1: novel autoantibodies in primary biliary cirrhosis., PMID:25243383
Autocrine hemokinin-1 functions as an endogenous adjuvant for IgE-mediated mast cell inflammatory responses., PMID:25201259
Hemokinin-1 as an adjuvant molecule enhancing humoral and memory responses to HBsAg DNA vaccination., PMID:22876773
HGF stimulates proliferation through the HGF/c-Met pathway in nasopharyngeal carcinoma cells., PMID:22783404
Involvement of tachykinins and NK1 receptor in the joint inflammation with collagen type II-specific monoclonal antibody-induced arthritis in mice., PMID:22687356
Identification of new autoantigens for primary biliary cirrhosis using human proteome microarrays., PMID:22647870
Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme., PMID:21242296
Antibodies against the voltage-dependent anion channel (VDAC) and its protective ligand hexokinase-I in children with autism., PMID:20576296
Hemokinin-1 activates the MAPK pathway and enhances B cell proliferation and antibody production., PMID:20208012
Expression of tissue and plasma kallikreins and kinin B1 and B2 receptors in lung cancer., PMID:18713009
Cleavage of disulfide bonds in mouse spermatogenic cell-specific type 1 hexokinase isozyme is associated with increased hexokinase activity and initiation of sperm motility., PMID:18509164
Novel expression of kallikreins, kallikrein-related peptidases and kinin receptors in human pleural mesothelioma., PMID:17976017
Pharmacoproteomics study of cetuximab in nasopharyngeal carcinoma., PMID:17137327
Association of the pre-B cell receptor (BCR) expression level with the quality of pre-BII cell differentiation reveals hierarchical pre-BCR function., PMID:17007932
Expression and preliminary characterization of recombinant human tissue kallikrein in egg white of laying hens., PMID:16830865
High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays., PMID:16510109
Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases., PMID:16086736
Antitumor effect and enhancement of cytotoxic drug activity by cetuximab in nasopharyngeal carcinoma cells., PMID:15796181
Homophilic anchorage of brain-hexokinase to mitochondria-porins revealed by specific-peptide antibody cross recognition., PMID:15562563
Hemokinins and endokinins., PMID:15224188
Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma., PMID:14639656
Polyclonal and monoclonal antibodies to prostate-specific antigen can cross-react with human kallikrein 2 and human kallikrein 1., PMID:10197850
Targeting of a germ cell-specific type 1 hexokinase lacking a porin-binding domain to the mitochondria as well as to the head and fibrous sheath of murine spermatozoa., PMID:9450953
Mouse spermatogenic cell-specific type 1 hexokinase (mHk1-s) transcripts are expressed by alternative splicing from the mHk1 gene and the HK1-S protein is localized mainly in the sperm tail., PMID:9508088
Developmental expression of hexokinase 1 and 3 in rats., PMID:9452958
Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice., PMID:9135074
Expression of human glandular kallikrein, hK2, in mammalian cells., PMID:8968092
For research use only. Not for human or drug use.
