Anti-Human ASC/TMS1/PYCARD Nanobody (SAA1025)

Catalog No.

RHJ80802

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clonality

Monoclonal

Target

TMS1, CARD5, Caspase recruitment domain-containing protein 5, Apoptosis-associated speck-like protein containing a CARD, PYD and CARD domain-containing protein, ASC, PYCARD, hASC, Target of methylation-induced silencing 1

Concentration

1.53 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

Q9ULZ3

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1025

Nanoscale organization of the endogenous ASC speck., PMID:38047065

Discovery of VH domains that allosterically inhibit ENPP1., PMID:37400538

ASC nanobodies to counteract the consequences of inflammasome activation., PMID:35574976

Nanobodies dismantle post-pyroptotic ASC specks and counteract inflammation in vivo., PMID:35438238

From atoms to physiology: what it takes to really understand inflammasomes., PMID:31490557

L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction., PMID:31000719

Targeting endogenous proteins for degradation through the affinity-directed protein missile system., PMID:28490657

A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly., PMID:27069117

Document Download

Anti-Human ASC/TMS1/PYCARD Nanobody (SAA1025).pdf