NK Cells Modulate Dendritic Cell (DC) Signaling Pathways and DC Recruitment in Chlamydial Infection., PMID:40332391
The IL-21/IL-21R signaling axis regulates CD4+ T-cell responsiveness to IL-12 to promote bacterial-induced colitis., PMID:38498592
Detailed phenotypic and functional characterization of CMV-associated adaptive NK cells in rhesus macaques., PMID:36518759
Toll-Like Receptor 7 (TLR7) Mediated Transcriptomic Changes on Human Mast Cells., PMID:34616120
NanoString technology distinguishes anti-TIF-1γ+ from anti-Mi-2+ dermatomyositis patients., PMID:34043263
Gene expression profile of human T cells following a single stimulation of peripheral blood mononuclear cells with anti-CD3 antibodies., PMID:31324145
Behçet's disease: An immunogenetic perspective., PMID:30341905
Clinical significance of CD161+CD4+ T cells in the development of chronic antibody-mediated rejection in kidney transplant recipients., PMID:30011312
Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice., PMID:28989066
Polymorphisms of IL12RB2 May Affect the Natural History of Primary Biliary Cholangitis: A Single Centre Study., PMID:28299343
Dysfunction of hepatic regulatory T cells in experimental sclerosing cholangitis is related to IL-12 signaling., PMID:27965154
Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?, PMID:25599124
IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: implications for therapy., PMID:24375552
Recurrent Burkholderia gladioli suppurative lymphadenitis associated with neutralizing anti-IL-12p70 autoantibodies., PMID:23708995
[Update: Behçet's disease]., PMID:23138553
Cytokines and Behcet's disease., PMID:22197901
Bovine IFNGR2, IL12RB1, IL12RB2, and IL23R polymorphisms and MAP infection status., PMID:21597988
IL-12p35 promotes antibody-induced joint inflammation by activating NKT cells and suppressing TGF-beta., PMID:20581146
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants., PMID:19458352
Interactions between human NK cells and macrophages in response to Salmonella infection., PMID:19299734
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice., PMID:19188681
Differential distribution of both IL-12Rbeta chains in the plasma membrane of human T cells., PMID:19067026
Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population., PMID:18715339
Polymorphisms in the 5' flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population., PMID:18353079
IL-12 is required for anti-OX40-mediated CD4 T cell survival., PMID:18250420
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes., PMID:17236132
Associations between measles vaccine immunity and single-nucleotide polymorphisms in cytokine and cytokine receptor genes., PMID:17152005
Cutaneous lymphocyte antigen expression on activated lymphocytes and its association with IL-12R (beta1 and beta2), IL-2Ralpha, and CXCR3., PMID:16165116
Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy., PMID:16081683
The role of interleukin-10 in the differential expression of interleukin-12p70 and its beta2 receptor on patients with active or treated paracoccidioidomycosis and healthy infected subjects., PMID:15596413
RNA editing of interleukin-12 receptor beta2, 2451 C-to-U (Ala 604 Val) conversion, associated with atopy., PMID:15005728
Expression of interleukin 12 receptor (IL-12R) and IL-18R on CD4+ T cells from patients with rheumatoid arthritis., PMID:14994387
In vitro allergen-induced mRNA expression of signaling lymphocytic activation molecule by PBMC of patients with allergic rhinitis is increased during specific pollen immunotherapy., PMID:14657878
Reduced IL-2-induced IL-12 responsiveness in atopic children., PMID:14641604
Intranasal IL-12 produces discreet pulmonary and systemic effects on allergic inflammation and airway reactivity., PMID:12689651
Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rbeta2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells., PMID:12047756
Regulation of bovine IL-12R beta 2 subunit mRNA expression in bovine lymph node cells., PMID:12036584
Expression of the bovine high affinity IL-12 receptor beta2., PMID:11777529
TGF-beta and IL-10 regulation of IFN-gamma produced in Th2-type schistosome granulomas requires IL-12., PMID:11557514
Dysregulation of lymphocyte interleukin-12 receptor expression in Sézary syndrome., PMID:11442758
IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression., PMID:11298330
Expression and function of IL-12 and IL-18 receptors on human tonsillar B cells., PMID:11120812
Positive and negative regulation of IL-12 receptor expression of naive CD4(+) T cells by CD28/CD152 co-stimulation., PMID:11093132
Maintenance of IL-12-responsive CD4+ T cells during a Th2 response in Leishmania major-infected mice., PMID:10940890
Cytokine regulation of IL-12 receptor beta2 expression: differential effects on human T and NK cells., PMID:10820383
The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit., PMID:10760800
Mutations of the IL-12 receptor beta2 chain gene in atopic subjects., PMID:10600539
Autocrine regulation of IL-12 receptor expression is independent of secondary IFN-gamma secretion and not restricted to T and NK cells., PMID:10553047
Role of IL-12 in intrathymic negative selection., PMID:10510375
Therapy with a combination of low doses of interleukin 12 and chloroquine completely cures blood-stage malaria, prevents severe anemia, and induces immunity to reinfection., PMID:9916053
For research use only. Not for human or drug use.
