Catalog No.
RHJ12901
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
ARC, KIAA0278, Activity-regulated cytoskeleton-associated protein, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, hArc, Arg3.1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
Q7LC44
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0943
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies., PMID:40463123
Cryoelectron microscopy as a tool for illuminating activation mechanisms of human class A orphan G protein-coupled receptors., PMID:40286430
Correction: Structural characterization of two nanobodies targeting the ligand-binding pocket of human Arc., PMID:40131924
Direct observation of fluorescent proteins in gels: A rapid, cost-efficient, and quantitative alternative to immunoblotting., PMID:39924827
Nanobody-Mediated Cellular Uptake Maximizes the Potency of Polylysine Dendrimers While Preserving Solid Tumor Penetration., PMID:39910852
A Nanobody-Based Proximity Ligation Assay Detects Constitutive and Stimulus-Regulated Native Arc/Arg3.1 Oligomers in Hippocampal Neuronal Dendrites., PMID:39367947
Nanobody engineering: computational modelling and design for biomedical and therapeutic applications., PMID:38898362
Structural characterization of two nanobodies targeting the ligand-binding pocket of human Arc., PMID:38683783
Sortase-Catalyzed Protein Domain Inversion., PMID:38366985
Structure of the voltage-gated potassium channel KV1.3: Insights into the inactivated conformation and binding to therapeutic leads., PMID:37695839
Modular Site-Specific Conjugation of Nanobodies Using Two Co-Associating Tags., PMID:36430882
High-affinity anti-Arc nanobodies provide tools for structural and functional studies., PMID:35671319
Correction to: Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function., PMID:35357602
Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function., PMID:35307777
Evolving cryo-EM structural approaches for GPCR drug discovery., PMID:33957078
Novel aptamer to von Willebrand factor A1 domain (TAGX-0004) shows total inhibition of thrombus formation superior to ARC1779 and comparable to caplacizumab., PMID:33131252
A new drug for an old concept: aptamer to von Willebrand factor for prevention of arterial and microvascular thrombosis., PMID:33131243
Engineering the Orientation, Density, and Flexibility of Single-Domain Antibodies on Nanoparticles To Improve Cell Targeting., PMID:31917547
Pointing in the Right Direction: Controlling the Orientation of Proteins on Nanoparticles Improves Targeting Efficiency., PMID:30773887
Graded activation and free energy landscapes of a muscarinic G-protein-coupled receptor., PMID:27791003
[Treatment of thrombotic thrombocytopenic purpura]., PMID:25297774
Inherited and acquired thrombotic thrombocytopenic purpura (TTP) in adults., PMID:24802084
Inhibitors of the interaction between von Willebrand factor and platelet GPIb/IX/V., PMID:22918736
Cell-free selection of domain antibodies by in vitro compartmentalization., PMID:22886253
For research use only. Not for human or drug use.
