Catalog No.
PHD28801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VCL (Lys1020-Gln1134).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:2000-1:8000
Target
MV,Metavinculin,Vinculin,VCL
Purification
Purified by antigen affinity column.
Accession
P18206
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs., PMID:39992626
LAG Time in the Era of Immunotherapy-New Molecular Insights Into the Immunosuppression Mechanism of Lymphocyte Activation Gene-3., PMID:39887765
ALK-Rearranged Renal Cell Carcinoma: A Study of Three Cases With Clinicopathologic Features and Effect of Postoperative Adjuvant Immunotherapy., PMID:39626326
Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab., PMID:39209860
Engineering synthetic agonists for targeted activation of Notch signaling., PMID:39149362
Anti-allergic effect of vitamin C through inhibiting degranulation and regulating TH1/TH2 cell polarization., PMID:38415860
Potential Biomarkers Associated with Prognosis and Trastuzumab Response in HER2+ Breast Cancer., PMID:37686651
Functional Comparison between Endogenous and Synthetic Notch Systems., PMID:36107643
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD., PMID:35473441
The Pre-Transplant Non-HLA Antibody Burden Associates With the Development of Histology of Antibody-Mediated Rejection After Kidney Transplantation., PMID:35250981
[Anaplastic lymphoma kinase-translocation renal cell carcinoma: clinical and pathological analysis]., PMID:34979750
Dissecting EPPIN protease inhibitor domains in sperm motility and fertilizing ability: repercussions for male contraceptive development., PMID:34792600
The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualizing stimulus define the cells' potential for decidualization success., PMID:34524461
Immunoglobulin Free Light Chains as Inflammatory Biomarkers of Atrial Fibrillation., PMID:33017540
Immunoglobulin free light chains as an inflammatory biomarker of heart failure with myocarditis., PMID:32479987
Immunoglobulin free light chains: an inflammatory biomarker of diabetes., PMID:32424470
Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling., PMID:31914456
Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease., PMID:31462148
Circulating Anti-cytolethal Distending Toxin B and Anti-vinculin Antibodies as Biomarkers in Community and Healthcare Populations With Functional Dyspepsia and Irritable Bowel Syndrome., PMID:31356481
Autoantibody-targeted TAAs in pancreatic cancer: A comprehensive analysis., PMID:31255446
Second-Generation Biomarker Testing for Irritable Bowel Syndrome Using Plasma Anti-CdtB and Anti-Vinculin Levels., PMID:31152332
Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells., PMID:29392327
Fluctuation of zonulin levels in blood vs stability of antibodies., PMID:28883692
Gap junction-mediated regulation of endothelial cellular stiffness., PMID:28733642
Heterogeneous Cell Types in Single-cell-derived Clones of MCF7 and MDA-MB-231 Cells., PMID:28476800
Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study., PMID:27816808
A definitive blood test for post-infectious irritable bowel syndrome?, PMID:27682513
Integrin β4 and vinculin contained in exosomes are potential markers for progression of prostate cancer associated with taxane-resistance., PMID:25997717
Autoimmunity Links Vinculin to the Pathophysiology of Chronic Functional Bowel Changes Following Campylobacter jejuni Infection in a Rat Model., PMID:25424202
Screening of integrin-binding peptides in a laminin peptide library derived from the mouse laminin β chain short arm regions., PMID:24785228
Co-incubation of human spermatozoa with anti-VDAC antibody reduced sperm motility., PMID:24481077
Semi-quantitative measurement of specific proteins in human cumulus cells using reverse phase protein array., PMID:24148967
Bulky DNA adducts in human sperm associated with semen parameters and sperm DNA fragmentation in infertile men: a cross-sectional study., PMID:24073787
Bisphenol A and human health: a review of the literature., PMID:23994667
Sex sorting increases the permeability of the membrane of stallion spermatozoa., PMID:23567220
Screening of integrin-binding peptides from the laminin α4 and α5 chain G domain peptide library., PMID:22391228
Targets of anti-endothelial cell antibodies in pulmonary hypertension and scleroderma., PMID:22005913
Anti-metastatic effects of ginsenoside Rd via inactivation of MAPK signaling and induction of focal adhesion formation., PMID:21982435
Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach., PMID:21711540
Renal cell carcinoma with novel VCL-ALK fusion: new representative of ALK-associated tumor spectrum., PMID:21076462
Evaluation of a plasmid DNA-based anthrax vaccine in rabbits, nonhuman primates and healthy adults., PMID:19458488
Sarcomeric-alpha-actinin defective in vinculin-binding causes Z-line expansion and nemaline-like body formation in cultured chick myotubes., PMID:19166831
Safety and immunogenicity of a bivalent cytomegalovirus DNA vaccine in healthy adult subjects., PMID:18444883
PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition., PMID:17409395
[Preliminary study on expression of oviductin in mouse cervix]., PMID:16955791
The phosphorylation of vinculin on tyrosine residues 100 and 1065, mediated by SRC kinases, affects cell spreading., PMID:15229287
Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A., PMID:15068840
Modulation by heparin of the interaction of the A1 domain of Von Willebrand factor with glycoprotein Ib., PMID:10590063
Plasmid DNA malaria vaccine: tissue distribution and safety studies in mice and rabbits., PMID:10210142
Antigenicity of the Leishmania infantum histones H2B and H4 during canine viscerocutaneous leishmaniasis., PMID:9933463
For research use only. Not for human or drug use.
