Catalog No.
PHD27101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human LGALS3 (Met1-Ile250).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Mac-2 antigen,Lectin L-29,LGALS3,Galactose-specific lectin 3,35 kDa lectin,Galactoside-binding protein,CBP 35,L-31,Gal-3,Laminin-binding protein,Galectin-3,GALBP,IgE-binding protein,Carbohydrate-binding protein 35,MAC2
Purification
Purified by antigen affinity column.
Accession
P17931
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Discovery and affinity maturation of antibody fragments from an unfavorably enriched phage display selection by deep sequencing and machine learning., PMID:40473542
Galectin-3 modulates cellular infectivity and inflammatory response mediated by spike protein of SARS-CoV2., PMID:40253029
Immunohistochemical Expression of HBME-1 in a Spectrum of Thyroid Neoplasms., PMID:39881771
Bcl-2 and galectin-3 expression is associated with recurrence of ameloblastoma., PMID:39802810
Secreted LGALS3BP facilitates distant metastasis of breast cancer., PMID:39789641
Galectin-3 in metabolic disorders: mechanisms and therapeutic potential., PMID:39690058
Nanoparticle biosensors for cardiovascular disease detection., PMID:39681229
Fibrosis mechanisms in systemic sclerosis and new potential therapies., PMID:39656890
Evaluation of galectin-3 and titin in cats with a sarcomeric gene mutation associated with echocardiography., PMID:39619937
Immunohistochemical Study Protocol in Thyroid Pathology., PMID:39579319
The Clinical and Molecular Response of Pyoderma Gangrenosum to IL-23 Blockade: Result from a Proof-of-Concept Open-Label Clinical Trial., PMID:39547392
Basophils induce protumorigenic cytokines from A549 lung adenocarcinoma via mechanisms requiring IgE, galectin-3, and IL-3 priming., PMID:39432748
Gal-3 blocks the binding between PD-1 and pembrolizumab., PMID:39357979
Enhanced Association of Novel Cardiovascular Biomarkers Fetuin-A and Catestatin with Serological and Inflammatory Markers in Rheumatoid Arthritis Patients., PMID:39337398
The GPI sidechain of Toxoplasma gondii inhibits parasite pathogenesis., PMID:39302131
FOSL1-mediated LINC01566 negatively regulates CD4+ T-cell activation in myasthenia gravis., PMID:39113081
Galectin-3 contributes to pathogenesis of IgA nephropathy., PMID:39084257
PRRSV utilizes MALT1-regulated autophagy flux to switch virus spread and reserve., PMID:39081059
Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis., PMID:39026176
Integrated magneto-plasmonic nanostructures-based immunoassay for galectin-3 detection., PMID:39007190
Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2., PMID:38825040
Neutrophils impaired by anti-galectin-3 antibodies elicit inflammation of endothelial cells to aggregate the development of lupus cutaneous vasculitis., PMID:38757282
TLR2-ERK signaling pathway regulates expression of galectin-3 in a murine model of OVA-induced allergic airway inflammation., PMID:38754639
Expression of inducible nitric oxide synthase, nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3 in patients with gastroesophageal reflux disease, eosinophilic esophagitis, and in healthy controls: a semiquantitative image analysis of 3,3'-diaminobenzidine-stained esophageal biopsies., PMID:38679488
BAP31 Promotes Angiogenesis via Galectin-3 Upregulation in Neuroblastoma., PMID:38474195
Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma., PMID:38438589
Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids., PMID:38332916
Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2., PMID:38289348
Vdelta1 T cells are more resistant than Vdelta2 T cells to the immunosuppressive properties of galectin-3., PMID:38259448
Galectin-3-binding protein inhibits extracellular heparan 6-O-endosulfatse Sulf-2., PMID:38187586
Heterogeneity in intrahepatic macrophage populations and druggable target expression in patients with steatotic liver disease-related fibrosis., PMID:38162144
Inhibition of cancer cell‑platelet adhesion as a promising therapeutic target for preventing peritoneal dissemination of gastric cancer., PMID:38020309
Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma., PMID:37988837
Enzymatically-derived oligo-carrageenans interact with α-Gal antibodies and Galectin-3., PMID:37985065
Novel immune checkpoint targets: A promising therapy for cancer treatments., PMID:37979454
Clinical value of Cyclin D1 and P21 in the differential diagnosis of papillary thyroid carcinoma., PMID:37951919
Galectin-3 does not interact with RNA directly., PMID:37815932
The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif., PMID:37788323
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints., PMID:37749326
Identifying Similar Allergens and Potentially Cross-Reacting Areas Using Structural Database of Allergenic Proteins (SDAP) Tools and D-Graph., PMID:37737991
Resistance to anti-PD-1/anti-PD-L1: galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1., PMID:37701441
Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis., PMID:37652913
LGALS3BP is a potential target of antibody-drug conjugates in oral squamous cell carcinoma., PMID:37649401
IgG4-related cholangitis - a mimicker of fibrosing and malignant cholangiopathies., PMID:37598939
Galectin-3 Plays an Important Role in BMP7-Induced Cementoblastic Differentiation of Human Periodontal Ligament Cells by Interacting with Extracellular Components., PMID:37396953
Inhibition of LPS-Induced Inflammatory Response of Oral Mesenchymal Stem Cells in the Presence of Galectin-3., PMID:37371614
Chimera and Tandem-Repeat Type Galectins: The New Targets for Cancer Immunotherapy., PMID:37371482
Antibodies as Models and Tools to Decipher Candida albicans Pathogenic Development: Review about a Unique Monoclonal Antibody Reacting with Immunomodulatory Adhesins., PMID:37367572
TNF-α promotes CXCL-1/8 production in keratinocytes by downregulating galectin-3 through NF-κB and hsa-miR-27a-3p pathway to contribute psoriasis development., PMID:37358143
Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage., PMID:37298447
For research use only. Not for human or drug use.
