Catalog No.
PHD25301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CAPN2 (Leu45-Asp514).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:200, WB: 1:1000-1:4000
Target
Calpain M-type,Calcium-activated neutral proteinase 2,CANPL2,Calpain-2 catalytic subunit,CAPN2,Calpain large polypeptide L2,Calpain-2 large subunit,Millimolar-calpain,M-calpain,CANP 2
Concentration
1.38 mg/ml
Purification
Purified by antigen affinity column.
Accession
P17655
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Neurobiochemical, Peptidomic, and Bioinformatic Approaches to Characterize Tauopathy Peptidome Biomarker Candidates in Experimental Mouse Model of Traumatic Brain Injury., PMID:36635478
Early CALP2 expression and microglial activation are potential inducers of spinal IL-6 up-regulation and bilateral pain following motor nerve injury., PMID:29423951
Limited proteolysis as a tool to probe the tertiary conformation of dysferlin and structural consequences of patient missense variant L344P., PMID:28904177
Expression and localization of calpain 3 in the submandibular gland of mice., PMID:27295390
Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway., PMID:27121057
Calpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cells., PMID:27099352
Cardiac protective effects of dexrazoxane on animal cardiotoxicity model induced by anthracycline combined with trastuzumab is associated with upregulation of calpain-2., PMID:25634181
Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis., PMID:25341622
Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair., PMID:25143396
Cytoskeletal protein α-II spectrin degradation in the brain of repeated blast exposed mice., PMID:24412202
Prolonged androgen deprivation leads to overexpression of calpain 2: implications for prostate cancer progression., PMID:24297527
Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function., PMID:23558232
EGF-like factors induce expansion of the cumulus cell-oocyte complexes by activating calpain-mediated cell movement., PMID:22673225
For research use only. Not for human or drug use.
