Catalog No.
DGK80501
Expression system
Mammalian Cells
Species reactivity
General
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
S1PSphingosine-1-phosphate
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
LT1009
Clone ID
Sonepcizumab
Targeting Sphingolipids for Cancer Therapy., PMID:34737957
A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma., PMID:27727447
Antibody therapies and their challenges in the treatment of age-related macular degeneration., PMID:25725263
Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases., PMID:23789924
Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model., PMID:21946553
The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen., PMID:19815502
Blockade of sphingosine-1-phosphate reduces macrophage influx and retinal and choroidal neovascularization., PMID:18781584
For research use only. Not for human or drug use.
