Catalog No.
PHD15901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CREB1 (Lys122-Asp327).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
cAMP-responsive element-binding protein 1,CREB-1,CREB1,Cyclic AMP-responsive element-binding protein 1
Purification
Purified by antigen affinity column.
Accession
P16220
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The interaction between rumen microbiota and neurotransmitters plays an important role in the adaptation of phenological changes in Tibetan sheep., PMID:40414864
AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity., PMID:40010348
FSH exacerbates bone loss by promoting osteoclast energy metabolism through the CREB-MDH2-NAD+ axis., PMID:39880362
Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer's disease by capillary western blotting., PMID:38299128
Inactivation of pentraxin 3 suppresses M2-like macrophage activity and immunosuppression in colon cancer., PMID:38243273
Identification of novel prognostic autoantibodies in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone via a high-throughput antigen microarray., PMID:38133926
Neuronal survival factor TAFA2 suppresses apoptosis through binding to ADGRL1 and activating cAMP/PKA/CREB/BCL2 signaling pathway., PMID:37944639
The lncRNA expression profile signature of leukemia stem cells is altered upon PI3K/mTOR inhibition: an in vitro and in silico study., PMID:37470414
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma., PMID:36959380
Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats., PMID:36195733
Evaluation of site-specific methylation of the CMV promoter and its role in CHO cell productivity of a recombinant monoclonal antibody., PMID:35719211
Upregulation of Neogenin-1 by a CREB1-BAF47 Complex in Vascular Endothelial Cells is Implicated in Atherogenesis., PMID:35186922
Exonic variants in multiple myeloma patients associated with relapsed/ refractory and response to bortezomib regimens., PMID:35002457
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment., PMID:34855209
The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination., PMID:34556879
Regorafenib enhances antitumor immunity via inhibition of p38 kinase/Creb1/Klf4 axis in tumor-associated macrophages., PMID:33753566
Transcriptome analysis of the effect of diosgenin on autoimmune thyroiditis in a rat model., PMID:33737640
Anti-High Mobility Group Box-1 Monoclonal Antibody Attenuates Seizure-Induced Cognitive Decline by Suppressing Neuroinflammation in an Adult Zebrafish Model., PMID:33732146
Down Syndrome Critical Region 1 Reduces Oxidative Stress-Induced Retinal Ganglion Cells Apoptosis via CREB-Bcl-2 Pathway., PMID:33104163
CREB Participates in Paclitaxel-Induced Neuropathic Pain Genesis Through Transcriptional Activation of Dnmt3a in Primary Sensory Neurons., PMID:33051852
Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter., PMID:32577618
Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration., PMID:32332736
TGF‑β1 induces CREB1‑mediated miR‑1290 upregulation to antagonize lung fibrosis via Napsin A., PMID:32319530
Angiomatoid Fibrous Histiocytoma With ALK Expression in an Unusual Location and Age Group., PMID:32310859
Neuroprotective Methodologies in the Treatment of Multiple Sclerosis Current Status of Clinical and Pre-clinical Findings., PMID:32031075
Inflammatory signal induced IL-10 production of marginal zone B-cells depends on CREB., PMID:31216428
Modulating cAMP responsive element binding protein 1 attenuates functional and behavioural deficits in rat model of neuropathic pain., PMID:30964189
ILF2 Directly Binds and Stabilizes CREB to Stimulate Malignant Phenotypes of Liver Cancer Cells., PMID:30881868
Caffeine inhibits hypoxia-induced nuclear accumulation in HIF-1α and promotes neonatal neuronal survival., PMID:30822423
SP1, MYC, CTNNB1, CREB1, JUN genes as potential therapy targets for neuropathic pain of brain., PMID:30478830
Therapeutic response of metastatic angiomatoid fibrous histiocytoma carrying EWSR1-CREB1 fusion to the interleukin-6 receptor antibody tocilizumab., PMID:29932283
CD11c-Specific Deletion Reveals CREB as a Critical Regulator of DC Function during the Germinal Center Response., PMID:29854847
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA., PMID:29770701
Genome-Wide Mapping of DNA Accessibility and Binding Sites for CREB and C/EBPβ in Vasopressin-Sensitive Collecting Duct Cells., PMID:29572403
Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects., PMID:29126434
Immunocytochemistry and fluorescence imaging efficiently identify individual neurons with CRISPR/Cas9-mediated gene disruption in primary cortical cultures., PMID:28764650
Biological impact of advanced glycation endproducts on estrogen receptor-positive MCF-7 breast cancer cells., PMID:28712835
Korean Red Ginseng Extract Enhances the Anticancer Effects of Sorafenib through Abrogation of CREB and c-Jun Activation in Renal Cell Carcinoma., PMID:28544385
Crosstalk between signals initiated from TLR4 and cell surface BAFF results in synergistic induction of proinflammatory mediators in THP-1 cells., PMID:28374824
Inhibition of JNK by pi class of glutathione S-transferase through PKA/CREB pathway is associated with carnosic acid protection against 6-hydroxydopamine-induced apoptosis., PMID:28288932
Reverse phase protein arrays enable glioblastoma molecular subtyping., PMID:27858266
The microRNA miR-124 suppresses seizure activity and regulates CREB1 activity., PMID:26996991
Chronic TCDD exposure results in the dysregulation of gene expression in splenic B-lymphocytes and in the impairments in T-cell and B-cell differentiation in mouse model., PMID:26899660
Opposite Sex Contact and Isolation: A Novel Depression/Anxiety Model., PMID:26781876
Long-Lasting Activation of the Transcription Factor CREB in Sensory Neurons by Interleukin-1β During Antigen-Induced Arthritis in Rats: A Mechanism of Persistent Arthritis Pain?, PMID:26473326
Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice., PMID:26352378
CP-154,526 Modifies CREB Phosphorylation and Thioredoxin-1 Expression in the Dentate Gyrus following Morphine-Induced Conditioned Place Preference., PMID:26313266
Screening of the Human Kinome Identifies MSK1/2-CREB1 as an Essential Pathway Mediating Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication during Primary Infection., PMID:26109721
Colorectal Carcinogenesis: Connecting K-RAS-Induced Transformation and CREB Activity In Vitro and In Vivo., PMID:25934695
Insulin-like growth factor-II regulates bone sialoprotein gene transcription., PMID:25895664
For research use only. Not for human or drug use.
