Catalog No.
PHD05401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PKM (Met1-Pro531).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PK2,Opa-interacting protein 3,THBP1,Tumor M2-PK,PKM,Pyruvate kinase muscle isozyme,Thyroid hormone-binding protein 1,PK3,Pyruvate kinase 2/3,p58,CTHBP,PKM2,Pyruvate kinase PKM,OIP-3,Cytosolic thyroid hormone-binding protein,OIP3
Purification
Purified by antigen affinity column.
Accession
P14618
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Exploration of Nitrotyrosine-Containing Proteins and Peptides by Antibody-Based Enrichment Strategies., PMID:38342410
Hemoglobin Protects Enamel against Intrinsic Enamel Erosive Demineralization., PMID:38198757
AMPK Drives Both Glycolytic and Oxidative Metabolism in T Cells During Graft-versus-host Disease., PMID:37398326
Lysine Acetylome of Breast Cancer-Derived Small Extracellular Vesicles Reveals Specific Acetylation Patterns for Metabolic Enzymes., PMID:37189694
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer: final 10-year analysis of the open-label, single-arm, phase 2 APT trial., PMID:36858723
Evaluation of the theoretical risk of cross-reactivity among recently identified food allergens for dogs., PMID:36043337
Monitoring of SARS-CoV-2 antibodies using dried blood spot for at-home collection., PMID:35388074
Need for aligning the definition and reporting of cytokine release syndrome (CRS) in immuno-oncology clinical trials., PMID:35219582
The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualizing stimulus define the cells' potential for decidualization success., PMID:34524461
Activation of PKM2 metabolically controls fulminant liver injury via restoration of pyruvate and reactivation of CDK1., PMID:34425230
Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycolysis, gating pyruvate generation, and increasing pyruvate flux into the TCA cycle., PMID:34288605
Single-Cell RNA Sequencing Analysis of the Immunometabolic Rewiring and Immunopathogenesis of Coronavirus Disease 2019., PMID:33936072
Metabolic pathways underlying GATA6 regulating Trastuzumab resistance in Gastric Cancer cells based on untargeted metabolomics., PMID:33173435
Immuno-cytometric detection of circulating cell free methylated DNA, post-translationally modified histones and micro RNAs using semi-conducting nanocrystals., PMID:33167226
PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation., PMID:32697823
Glycolytic competence in gastric adenocarcinomas negatively impacts survival outcomes of patients treated with salvage paclitaxel-ramucirumab., PMID:32372141
Quantum dot nanoconjugates for immuno-detection of circulating cell-free miRNAs., PMID:31816728
T-cell-derived extracellular vesicles regulate B-cell IgG production via pyruvate kinase muscle isozyme 2., PMID:31480861
Multi-dimensional immunoproteomics coupled with in vitro recapitulation of oncogenic NRASQ61R identifies diagnostically relevant autoantibody biomarkers in thyroid neoplasia., PMID:31326556
Subcellular compartmentalization of PKM2 identifies anti-PKM2 therapy response in vitro and in vivo mouse model of human non-small-cell lung cancer., PMID:31120964
Pyruvate Kinase Muscle-1 Expression Appears to Drive Lactogenic Behavior in CHO Cell Lines, Triggering Lower Viability and Productivity: A Case Study., PMID:30179303
The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis., PMID:29996098
Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction., PMID:28436957
Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma., PMID:26863356
Sunitinib activates Axl signaling in renal cell cancer., PMID:26815723
Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using Pharmacokinetic Modeling: Initial Experience in Patients With Early Arthritis., PMID:26473331
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer., PMID:25564897
Cellular localization of the atypical isoforms of protein kinase C (aPKCζ/PKMζ and aPKCλ/ι) on the neuromuscular synapse., PMID:24135336
Model-based, semiquantitative and time intensity curve shape analysis of dynamic contrast-enhanced MRI: a comparison in patients undergoing antiangiogenic treatment for recurrent glioma., PMID:21954019
Molecular surveillance of hepatitis and tuberculosis infections in a cohort exposed to methyl isocyanate., PMID:21468906
Inflammatory response to isocyanates and onset of genomic instability in cultured human lung fibroblasts., PMID:19283680
A novel pyruvate kinase (PK-S) from boar spermatozoa is localized at the fibrous sheath and the acrosome., PMID:17641091
Mouse-heart grafts expressing an incompatible carbohydrate antigen. II. Transition from accommodation to tolerance., PMID:14966409
Induction of immune tolerance to a transplantation carbohydrate antigen by gene therapy with autologous lymphocytes transduced with adenovirus containing the corresponding glycosyltransferase gene., PMID:14737089
The homeodomain-interacting kinase PKM (HIPK-2) modifies ND10 through both its kinase domain and a SUMO-1 interaction motif and alters the posttranslational modification of PML., PMID:12565818
Tolerance induction to a mammalian blood group-like carbohydrate antigen by syngeneic lymphocytes expressing the antigen., PMID:12406874
Persistence of herpesvirus of eel Herpesvirus anguillae in farmed European eel Anguilla anguilla., PMID:11463096
Increased nuclear translocation of catalytically active PKC-zeta during mouse colonocyte hyperproliferation., PMID:10898766
Sp family members and nuclear factor-Y cooperatively stimulate transcription from the rat pyruvate kinase M gene distal promoter region via their direct interactions., PMID:10748033
Generation of the catalytic fragment of protein kinase C alpha in spastic canine basilar artery., PMID:9347985
Learning-induced alterations in hippocampal PKC-immunoreactivity: a review and hypothesis of its functional significance., PMID:9153071
Hyperphosphorylation of Tau and filopodial retraction following microinjection of protein kinase C catalytic subunits., PMID:8600297
Modulation of signal transduction in rat synaptoneurosomes by platelet activating factor., PMID:7546018
Developmental expression of the protein kinase C family in rat hippocampus., PMID:8026084
Inhibition of the calpain-mediated proteolysis of protein kinase C enhances lytic activity in human NK cells., PMID:1913839
Deficit of cell-mediated immunity, chromosomal alterations and defective DNA repair in a case of dyskeratosis congenita., PMID:7351274
For research use only. Not for human or drug use.
