Catalog No.
PHC97401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD107b/LAMP2 (Leu29-Gln366).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LGP-96,CD107b,LAMP2,CD107 antigen-like family member B,Lysosome-associated membrane glycoprotein 2,Lysosome-associated membrane protein 2,LAMP-2
Purification
Purified by antigen affinity column.
Accession
P13473
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
In vivo labeling reveals that degranulation is increased under supraphysiological TCR stimulation, but not infection, in CD8+ T cells from old mice., PMID:40478430
Enhanced therapeutic efficacy of anti-PD-1 blockade by targeting LAMP2A inhibits lysosomal degradation of STING and TBK1., PMID:40083918
Lysosomes accumulate at the perinuclear region of muscle cells during chick myogenesis., PMID:39252384
Immunoexpression Pattern of Autophagy-Related Proteins in Human Congenital Anomalies of the Kidney and Urinary Tract., PMID:38999938
Comprehensive knockout analysis of the RAB family small GTPases reveals an overlapping role of RAB2 and RAB14 in autophagosome maturation., PMID:38953305
Anti-LAMP-2 Antibody Seropositivity in Children with Primary Systemic Vasculitis Affecting Medium- and Large-Sized Vessels., PMID:38612581
Knockout validation of LAMP2A antibodies for immunostaining in human cancer cells., PMID:37194363
Recent topics related to etiology and clinical manifestations of cutaneous arteritis., PMID:36300176
Immunohistochemical Detection of the Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Formalin-Fixed and Paraffin-Embedded Tissues., PMID:36152248
Typical cutaneous small-vessel vasculitis induced by combined injection of antiphosphatidylserine/prothrombin complex antibody and anti-LAMP-2 antibody in normal rats., PMID:35876151
The Association of Serum Anti-Lysosomal-Associated Membrane Protein-2 Antibody with Vasculitis Combined with Hypertension., PMID:35356030
Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy., PMID:34685711
Implication of a lysosomal antigen in the pathogenesis of lupus erythematosus., PMID:33932829
Autoantibodies Against Lysosome Associated Membrane Protein-2 (LAMP-2) in Pediatric Chronic Primary Systemic Vasculitis., PMID:33613565
Alterations of serum levels of plasminogen, TNF-α, and IDO in granulomatosis with polyangiitis patients., PMID:33427113
Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung., PMID:33029283
Chaperone-Mediated Autophagy after Spinal Cord Injury., PMID:32233738
Systemic AAV9.LAMP2B injection reverses metabolic and physiologic multiorgan dysfunction in a murine model of Danon disease., PMID:32188720
Relationship between lysosomal-associated membrane protein-2 and anti-phosphatidylserine/prothrombin complex antibody in the pathogenesis of cutaneous vasculitis., PMID:31994486
Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells., PMID:31226464
Tumor cells induce LAMP2a expression in tumor-associated macrophage for cancer progression., PMID:30711520
Serum lysosomal-associated membrane protein-2 levels are increased in small and medium-vessel vasculitis, especially in polyarteritis nodosa., PMID:30620279
Characterization of the "Autophagic Flux" in Prostate Cancer Tissue Biopsies by LC3A/LAMP2a Immunofluorescence and Confocal Microscopy., PMID:30610722
Host cell protein LAMP-2 is the receptor for Trypanosoma cruzi surface molecule gp82 that mediates invasion., PMID:30609224
Development of a novel anti-HER2 scFv by ribosome display and in silico evaluation of its 3D structure and interaction with HER2, alone and after fusion to LAMP2B., PMID:30225583
Rituximab impedes natural killer cell function in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients: A pilot in vitro investigation., PMID:29587879
Cell surface markers for the identification and study of human naive pluripotent stem cells., PMID:29227830
Surface LAMP-2 Is an Endocytic Receptor That Diverts Antigen Internalized by Human Dendritic Cells into Highly Immunogenic Exosomes., PMID:28607115
Lysosomal Acidification in Cultured Astrocytes Using Nanoparticles., PMID:28456982
Cytotoxic CD8+ T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis., PMID:28452087
Identification of Putative Receptors for the Novel Adipokine CTRP3 Using Ligand-Receptor Capture Technology., PMID:27727322
Identification of LAMP2 Mutations in Early-Onset Danon Disease With Hypertrophic Cardiomyopathy by Targeted Next-Generation Sequencing., PMID:27460667
Effect of secondary anchor amino acid substitutions on the immunogenic properties of an HLA-A*0201-restricted T cell epitope derived from the Trypanosoma cruzi KMP-11 protein., PMID:26854383
Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer., PMID:26761524
Prosthetic Antigen Receptors., PMID:26230248
Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophages., PMID:25960020
Proteomics urine analysis of pregnant women suffering from multiple sclerosis., PMID:25793971
Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis., PMID:25644394
Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis., PMID:25629443
Early and irreversible recurrence MPO-ANCA-positive glomerulonephritis after renal transplantation., PMID:25345380
Successful treatment with plasma exchange for ANCA-negative pauci-immune crescentic glomerulonephritis with D-negative hemolytic uremic syndrome., PMID:25074840
Reproducibility and efficiency of serum-derived exosome extraction methods., PMID:24956264
Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes., PMID:24860120
Autoantibodies to hLAMP-2 in ANCA-negative pauci-immune focal necrotizing GN., PMID:24203998
[Neurological involvement in Wegener's granulomatosis]., PMID:24200609
Identification of a primary biliary cirrhosis associated protein as lysosome-associated membrane protein-2., PMID:24007661
Transplantation of human umbilical mesenchymal stem cells cures the corneal defects of mucopolysaccharidosis VII mice., PMID:23897660
Calpain 1 induce lysosomal permeabilization by cleavage of lysosomal associated membrane protein 2., PMID:23747342
Lysosomal-associated membrane protein-2 plays an important role in the pathogenesis of primary cutaneous vasculitis., PMID:23704322
Pathogenesis of rapidly progressive glomerulonephritis: what do we learn?, PMID:23689582
For research use only. Not for human or drug use.
