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Anti-IL7 Polyclonal Antibody

Catalog #:   PHC96801 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P13232
Overview

Catalog No.

PHC96801

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IL7 (Asp26-His177).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

IL-7,Interleukin-7,IL7

Purification

Purified by antigen affinity column.

Accession

P13232

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IL7 antibody (PHC96801) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 19 kDa
    Observed MW: 19 kDa
References

Systemic secukinumab treatment in patients with ankylosing spondylitis: the relationship between systemic and tear proinflammatory cytokines and ocular surface findings-a pilot study., PMID:40394377

Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset., PMID:40383826

Trifunctional antibody-cytokine fusion protein formats for tumor-targeted combination of IL-15 with IL-7 or IL-21., PMID:40370435

ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis., PMID:40328742

Comparative Efficacy of Interleukin-7 and -15 Blockade in Alleviating Experimental Chronic Uveitis and Suppressing Pathogenic Memory CD4+ T Cells., PMID:40323267

Bone marrow mesenchymal stem cells alleviate liver fibrosis after rat liver transplantation through JAK1/STAT5 pathway., PMID:40312752

Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer., PMID:40299475

Enhanced Immunity and Infection Resistance in Mice Through Co-Expression of Porcine IL-3, IL-7, and IL-15 Fusion Molecules in Yarrowia lipolytica., PMID:40282231

Harnessing cytokine immunocomplexes and cytokine fusion proteins for cancer Therapy: Mechanisms and clinical potential., PMID:40233680

Novel first-trimester serum biomarkers for early prediction of gestational diabetes mellitus., PMID:40221404

Single-cell transcriptomic analysis reveals AP-1 downregulation remodels bone marrow environment and contributes to osteopenia in ovariectomized mice., PMID:40213116

Discovery of a new anti-γc antibody in clinical development for the treatment of autoimmune diseases., PMID:40163668

Pre-B-cell leukemia transcription factor 1 contributes to liver fibrosis by enabling IL-7 signaling in HSC., PMID:40080840

Immune memory in hepatitis E virus: a comparative study of natural infection and vaccination in a nursing home population., PMID:40073099

Analysis of proinflammatory cytokine responses in Takayasu arteritis., PMID:40060124

IL-7 Immunotherapies: Current Applications and Engineering Opportunities., PMID:39981682

Targeting γc family cytokines with biologics: current status and future prospects., PMID:39967341

Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19., PMID:39896810

Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective ultrasound cohort study., PMID:39863304

From phenotypic to molecular diagnosis: Insights from a clinical immunology service focused on inborn errors of immunity in Colombia., PMID:39836844

A Multiple-Model-Informed Drug-Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab., PMID:39776360

Toripalimab plus chemotherapy for first line treatment of advanced non-small cell lung cancer (CHOICE-01): final OS and biomarker exploration of a randomized, double-blind, phase 3 trial., PMID:39715755

Tocilizumab and immune signatures for targeted management of cytokine release syndrome in immune checkpoint therapy., PMID:39701282

Novel plasma cytokines identified and validated in children during lead exposure according to the new updated BLRV., PMID:39639084

A Phase II Open-Label, Randomized Clinical Trial of Atezolizumab with or without Human Recombinant IL-7 (CYT107) in Advanced Urothelial Cancer., PMID:39576210

IL-7 promotes mRNA vaccine-induced long-term immunity., PMID:39550592

Detectability of cytokine and chemokine using ELISA, following sample-inactivation using Triton X-100 or heat., PMID:39500912

Rapamycin Prevents Expansion of Costimulation Blockade-resistant CD8+ Alloreactive Memory Cells following Depletional Induction in Renal Transplant Recipients., PMID:39302088

Immunologic Crosstalk and Host-Specific Immune Signature Associated with Dengue., PMID:39281909

Comparison of serum cytokines and chemokines levels and clinical significance in patients with pemphigus vulgaris-A retrospective study., PMID:39246287

Good manufacturing practice-grade generation of CD19 and CD123-specific CAR-T cells using piggyBac transposon and allogeneic feeder cells in patients diagnosed with B-cell non-Hodgkin lymphoma and acute myeloid leukemia., PMID:39192973

Profound T Lymphocyte and DNA Repair Defect Characterizes Schimke Immuno-Osseous Dysplasia., PMID:39153074

An IL-7 fusion protein targeting EDA fibronectin upregulates TCF1 on CD8+ T-cells, preferentially accumulates to neoplastic lesions, and boosts PD-1 blockade., PMID:39142716

Interleukin-7 Risk Allele, Lymphocyte Counts, and Autoantibodies for Prediction of Risk of Immune-Related Adverse Events in Patients Receiving Atezolizumab plus Bevacizumab Therapy for Unresectable Hepatocellular Carcinoma., PMID:39079513

Elevated aqueous TNF-α levels are associated with more severe functional and anatomic findings in eyes with diabetic macular oedema., PMID:39072984

A human autoimmune organoid model reveals IL-7 function in coeliac disease., PMID:39048815

rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors., PMID:39043602

Clinical characteristics, immunological alteration and distinction of MOG-IgG-associated disorders and GFAP-IgG-associated disorders., PMID:39002186

Peripheral blood immune parameters, response, and adverse events after neoadjuvant chemotherapy plus durvalumab in early-stage triple-negative breast cancer., PMID:39002068

Interleukin-7-based identification of liver lymphatic endothelial cells reveals their unique structural features., PMID:38966234

A "Prime and Expand" strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy., PMID:38960949

A Mendelian randomization study investigating the causal relationships between inflammation and immunoglobulin A nephropathy., PMID:38861759

Adjunctive immunotherapeutic agents in patients with sepsis and septic shock: a multidisciplinary consensus of 23., PMID:38689337

Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen., PMID:38603720

Choosing T-cell sources determines CAR-T cell activity in neuroblastoma., PMID:38601159

Omenn Syndrome in Two Infants with Different Hypomorphic Variants in Janus Kinase 3., PMID:38598033

Adoptive immunotherapy with cells from tumor-draining lymph nodes activated and expanded in vitro., PMID:38548419

B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters., PMID:38529494

IL7 increases targeted lipid nanoparticle-mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation., PMID:38513098

rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors., PMID:38471713

Datasheet

Document Download

Anti-IL7 Polyclonal Antibody.pdf

 

$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-IL7 Polyclonal Antibody [PHC96801]
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