Catalog No.
PHC95701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SRC (Tyr187-Leu536).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SRC1,p60-Src,Proto-oncogene tyrosine-protein kinase Src,Proto-oncogene c-Src,SRC,pp60c-src
Purification
Purified by antigen affinity column.
Accession
P12931
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Unusually Broad-spectrum small-molecule sensing using a single protein scaffold., PMID:40462935
Siglec6 CAR T cells suppressed progression of AML via inhibiting Siglec6 and SHP2 induced Src and ERK signaling activation., PMID:40436895
Last Resort? Rationale for Comprehensive Molecular Analysis in Treatment-Refractory R/M HNSCC: A Case Report of Remarkable Response to Sacituzumab Govitecan Following Molecular and Functional Characterization., PMID:40427091
PRL3-zumab as an anti-angiogenic therapy in neovascular eye diseases., PMID:40410189
Evaluation of Anti-SARS-CoV-2 IgG Responses in a Clinical Study of a Biosimilar Candidate to Denosumab Using Singlicate Analysis., PMID:40408051
HMGB1 Regulates Adipocyte Lipolysis via Caveolin-1 Signaling: Implications for Metabolic and Cardiovascular Diseases., PMID:40362460
[Mechanism of Naoxintong Capsules in treatment of rats with multiple cerebral infarctions and myocardial injury based on HIF-1α/VEGF pathway]., PMID:40350881
Flow Cytometry-Based Rapid Assay for Antigen Specific Antibody Relative Affinity in SRBC-Immunized Mouse Models., PMID:40332147
Leveraging neonatal Fc receptor (FcRn) to enhance antibody transport across the blood brain barrier., PMID:40319060
TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis., PMID:40308591
Seroprevalence of anti-influenza antibodies in humans and characterization of seasonal influenza viruses isolated in Russia during the 2023-2024 flu season., PMID:40307541
MUC1-C dependency in drug resistant HR+/HER2- breast cancer identifies a new target for antibody-drug conjugate treatment., PMID:40287441
Cx45 regulation by kinases and impact of expression in heart failure., PMID:40280467
Treatment with human placental extracts inhibits allergic rhinitis by modulating AMPK/SHP1/SHP2/STING signaling., PMID:40280106
Effect of heterologous intranasal iNCOVACC® vaccination as a booster to two-dose intramuscular Covid-19 vaccination series: a randomized phase 3 clinical trial., PMID:40269252
Heparan sulfate proteoglycans remodel SARS-CoV-2 spike conformation to allow integrin interaction and infection of endothelial cells., PMID:40248367
Targeting LTBP2 Derived from Cancer-Associated Fibroblasts Sensitizes Esophageal Squamous Cell Carcinoma to Chemotherapy., PMID:40245188
A microprotein encoded by LINC00263 promotes breast cancer osteolytic bone metastasis by inducing osteoclastogenesis and inhibiting osteoclast ferroptosis., PMID:40221529
The feasible role of soluble E‑cadherin in spheroidogenesis of HCT116 colorectal cancer cells, a candidate biomarker for liquid biopsy., PMID:40182609
C-C motif chemokines ligand 7 contributes to metabolic dysfunction-associated steatotic liver disease by enabling redox-sensitive induction of hypermethylated in cancer 1., PMID:40157597
Dose-Dependent Effect of DNA Vaccine pVAX-H5 Encoding a Modified Hemagglutinin of Influenza A (H5N8) and Its Cross-Reactivity Against A (H5N1) Influenza Viruses of Clade 2.3.4.4b., PMID:40143259
Malignant hypertension, and if it was scleroderma? Lessons from two cases., PMID:40109088
Tick-borne encephalitis virus seroprevalence and infection incidence in Switzerland, 2020-2021., PMID:40069290
Engineered SH3-Derived Sherpabodies Function as a Modular Platform for Targeted T-cell Immunotherapy., PMID:40029291
Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis., PMID:40010102
Stimulation of endothelin-1 production by autoantibodies present in patients with scleroderma renal crisis., PMID:39956166
Elucidating the pharmacological foundations and mechanisms of the Sihai Shuyu formula in treating Graves' disease through integrated serum metabolomics and network pharmacology with molecular docking techniques., PMID:39950029
Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma., PMID:39949781
Synergistic Inhibition of Drug Resistant KRAS Mutant Non-Small Cell Lung Cancer by Co-Targeting AXL and SRC., PMID:39941857
Research progress in bifunctional small molecules for cancer immunotherapy., PMID:39919914
Jian Pi Hua Tan Fang Reverses Trastuzumab Resistance of HER2-Positive Gastric Cancer Through PI3K/AKT/mTOR Pathway: Integrating Network Pharmacology, Molecular Docking and Experimental Validation., PMID:39917999
Management of disease progression after autologous hematopoietic stem cell transplantation in systemic sclerosis: Results from an international questionnaire-based study., PMID:39914262
Deletion of PTP4A3 phosphatase in high-grade serous ovarian cancer cells decreases tumorigenicity and produces marked changes in intracellular signaling pathways and cytokine release., PMID:39892999
The impact of signaling pathways on the desmosome ultrastructure in pemphigus., PMID:39882246
Synthesis and evaluation of KX-01 analogs with an exploration of linker attachment points for antibody-drug conjugates., PMID:39880175
Probability of achieving bone mineral density treatment goals with denosumab treatment in postmenopausal women with osteoporosis., PMID:39861972
Jet Injection of Naked mRNA Encoding the RBD of the SARS-CoV-2 Spike Protein Induces a High Level of a Specific Immune Response in Mice., PMID:39852844
Perfluorooctane sulfonate attenuates IgE/Ag-stimulated mast cell activation and anaphylactic responses via activating SHP-1 pathway., PMID:39827624
[Mechanism of Bone-metastatic LUAD Cells Promoting Angiogenesis
Through HGF/YAP Signaling Pathway]., PMID:39800475
Dietary Linolenic Acid Enhances IgE Binding to Bovine α-Lactalbumin/β-Lactoglobulin and Promotes KU812 Basophil Degranulation via Upregulation of the Lyn/Syk Pathway., PMID:39772611
VGLL fusions define a new class of intraparenchymal central nervous system schwannoma., PMID:39713960
BilT03: Phase 1b/2 multicenter trial of nivolumab with 5-fluorouracil and liposomal irinotecan for previously treated advanced biliary tract cancer., PMID:39701097
KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE-mediated Activation., PMID:39676406
Phenotype of diffuse cutaneous systemic sclerosis patients with positive anticentromere antibodies: A systematic literature review and meta-analysis., PMID:39657361
Extrajunctional CLDN10 cooperates with LAT1 and accelerates clear cell renal cell carcinoma progression., PMID:39639312
CD11b deficiency attenuates the ischemia/reperfusion-induced AKI-to-CKD process by regulating macrophage polarization., PMID:39612192
Potential of epithelial membrane protein 3 as a novel therapeutic target for human breast cancer., PMID:39611484
Antimicrobial Peptide Pro10-1D Exhibits Anti-Allergic Activity: A Promising Therapeutic Candidate., PMID:39596204
Association of Antibody-Drug Conjugate (ADC) Target Expression and Interstitial Lung Disease (ILD) in Non-Small-Cell Lung Cancer (NSCLC): Association or Causation or Neither?, PMID:39594708
Scleroderma renal crisis, an increasingly rare but persistently challenging condition: a retrospective cohort study., PMID:39555050
For research use only. Not for human or drug use.
