Catalog No.
PHA89101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PHLPP1 (Ser1168-Thr1425).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
KIAA0606, Pleckstrin homology domain-containing family E member 1, hSCOP, PHLPP, SCOP, PHLPP1, PH domain leucine-rich repeat-containing protein phosphatase 1, PLEKHE1, Suprachiasmatic nucleus circadian oscillatory protein, PH domain-containing family E member 1
Purification
Purified by antigen affinity column.
Accession
O60346
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The roles of phosphorylation of signaling proteins in the prognosis of acute myeloid leukemia., PMID:39035053
The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels., PMID:36092718
Epstein-Barr Virus Induces Lymphangiogenesis and Lympth Node Metastasis via Upregulation of VEGF-C in Nasopharyngeal Carcinoma., PMID:34654722
CXCL13 is a differentiation- and hypoxia-induced adipocytokine that exacerbates the inflammatory phenotype of adipocytes through PHLPP1 induction., PMID:31710352
PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells., PMID:26760962
MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1., PMID:26107137
Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies., PMID:25827478
MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation., PMID:23812097
Response: 'Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin'., PMID:23681440
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin., PMID:23229585
Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells., PMID:20861921
Insulin receptor kinase-independent signaling via tyrosine phosphorylation of phosphatase PHLPP1., PMID:19277985
For research use only. Not for human or drug use.
