Catalog No.
PHC82701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CHGA (Met158-Gly457).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Vasostatin I,Pituitary secretory protein I,Vasostatin II,Chromogranin-A,SP-I,CgA,SL21,CHGA
Purification
Purified by antigen affinity column.
Accession
P10645
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
[Establishment of a sandwich ELISA method for CHGA in saliva samples and its preliminary application in stress detection]., PMID:40260565
Enhanced Association of Novel Cardiovascular Biomarkers Fetuin-A and Catestatin with Serological and Inflammatory Markers in Rheumatoid Arthritis Patients., PMID:39337398
CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes., PMID:39214091
The Significance of Insulinoma-Associated Protein 1 in the Pathological Diagnosis of Small-Cell Lung Cancer in Biopsy Specimens., PMID:38192158
[Pancreatic β-cell dedifferentiation detected by flow cytometry]., PMID:36456511
Histological, histochemical, ultrastructural and immunohistochemical identification and characterization of the neurosecretory cells of the adult rabbit's adrenal medulla., PMID:35119700
Chromogranin A Deficiency Confers Protection From Autoimmune Diabetes via Multiple Mechanisms., PMID:34497137
Novel Insight in Idiopathic Normal Pressure Hydrocephalus (iNPH) Biomarker Discovery in CSF., PMID:34360799
Chromogranin Serves as Novel Biomarker of Endocrine and Gastric Autoimmunity., PMID:32436949
A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery., PMID:31806623
Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement., PMID:30796053
NordiQC Assessments of Chromogranin A Immunoassays., PMID:30653032
Effective preparation of a monoclonal antibody against human chromogranin A for immunohistochemical diagnosis., PMID:29728076
Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer., PMID:29191973
Alcohol Feeding in Mice Promotes Colonic Hyperpermeability and Changes in Colonic Organoid Stem Cell Fate., PMID:28992396
Neuroendocrine differentiation in basal cell carcinoma., PMID:28548901
Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion., PMID:28220294
Neuroendocrine Differentiation in Thymic Carcinomas: A Diagnostic Pitfall: An Immunohistochemical Analysis of 27 Cases., PMID:27124922
Long-Term Insulin Independence in Type 1 Diabetes Mellitus Using a Simplified Autologous Stem Cell Transplant., PMID:26859103
Autoantibodies to chromogranin A are potential diagnostic biomarkers for non-small cell lung cancer., PMID:26186986
Comparison of chromogranin A (CgA) levels in serum and plasma (EDTA2K) and the respective reference ranges in healthy males., PMID:25754282
Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine., PMID:24603700
Vasostatin-1 antigenic epitope mapping for induction of cellular and humoral immune responses to chromogranin A autoantigen in NOD mice., PMID:24443235
Chromogranin A is a T cell antigen in human type 1 diabetes., PMID:24239002
Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers., PMID:22412953
Targeting protein kinase C by Enzastaurin restrains proliferation and secretion in human pancreatic endocrine tumors., PMID:21606156
Chromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga(364-384))., PMID:21052719
Catestatin attenuates the effects of intrathecal nicotine and isoproterenol., PMID:19785998
The importance of chromogranin A in the development and function of endocrine pancreas., PMID:18722481
Multiple minute nests of incidentally detected paraganglionic cells associated with urothelial carcinoma of the urinary bladder in a 73-year-old woman., PMID:18470683
Elevated plasma chromogranin A levels attributable to assay interference: a source of diagnostic confusion., PMID:16939951
Neuroendocrine modulation induced by selective blockade of TNF-alpha in rheumatoid arthritis., PMID:16855170
Insulin-like growth factor-1 increases intracellular calcium concentration in human primary neuroendocrine pancreatic tumor cells and a pancreatic neuroendocrine tumor cell line (BON-1) via R-type Ca2+ channels and regulates chromogranin a secretion in BON-1 cells., PMID:16424676
Differential expression and processing of chromogranin A and secretogranin II in relation to the secretory status of endocrine cells., PMID:16357044
Measurement of plasma chromogranin A concentrations for assessment of stress responses in dogs with insulin-induced hypoglycemia., PMID:16273918
Comparison between two methods in the determination of circulating chromogranin A in neuroendocrine tumors (NETs): results of a prospective multicenter observational study., PMID:16240843
An immunohistochemical study of chromogranin A and Sp-1 immunoreactive cells in the gastrointestinal tract of ovariectomized rats., PMID:16131820
Expression of amino acid sequences of the chromogranin A molecule and synaptic vesicle protein 2 in neuroendocrine tumors of the lung., PMID:15906087
High plasma levels of human chromogranin A and adrenomedullin in patients with pheochromocytoma., PMID:15850005
Accuracy and clinical correlates of two different methods for chromogranin A assay in neuroendocrine tumors., PMID:15646836
Clinical significance of elevated serum chromogranin A levels., PMID:15513336
Selective reduction of chromogranin A-like immunoreactivities in the prefrontal cortex of schizophrenic subjects: a postmortem study., PMID:15337252
A panel of 11 region-specific radioimmunoassays for measurements of human chromogranin A., PMID:14749043
Chromogranin A protects vessels against tumor necrosis factor alpha-induced vascular leakage., PMID:14734634
Chromogranin A as serum marker of pituitary adenomas., PMID:14616890
Modulation of prostate carcinoma cell growth and apoptosis by chromogranin A., PMID:14532847
[Clinical significant of serum chromogranin A levels for diagnosing pheochromocytoma in hypertensive patients]., PMID:12945223
Chromogranin a processing in human pituitary adenomas and carcinomas: analysis with region-specific antibodies., PMID:12746561
A comparison between three commercial kits for chromogranin A measurements., PMID:12740022
Neuroendocrine differentiation in carcinoma of the breast. Tyramide signal amplification discloses chromogranin A-positive tumour cells in more breast tumours than previously realized., PMID:12529020
For research use only. Not for human or drug use.
