Catalog No.
YPJ53501
Expression system
E. coli
Species
Sus scrofa (Pig)
Protein length
Ala33-Asn190
Predicted molecular weight
20.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
F1SH68
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin 22, IL22
Supplemented with Astragalus dregs improves growth performance, immunity, and antioxidant capacity in fattening pigs., PMID:39943934
Probiotic-derived extracellular vesicles alleviate AFB1-induced intestinal injury by modulating the gut microbiota and AHR activation., PMID:39529091
Expression of key immune genes in polarized porcine monocyte-derived macrophage subsets., PMID:39427365
Chlorogenic Acid Enhances the Intestinal Health of Weaned Piglets by Inhibiting the TLR4/NF-κB Pathway and Activating the Nrf2 Pathway., PMID:39337442
AhR ligands from LGG metabolites promote piglet intestinal ILC3 activation and IL-22 secretion to inhibit PEDV infection., PMID:39012142
Intranasal B5 promotes mucosal defence against Actinobacillus pleuropneumoniae via ameliorating early immunosuppression., PMID:38378464
Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis., PMID:38317607
Single-Cell Transcriptional Analysis of Lamina Propria Lymphocytes in the Jejunum Reveals Innate Lymphoid Cell-like Cells in Pigs., PMID:37975680
Role of iron in host-microbiota interaction and its effects on intestinal mucosal growth and immune plasticity in a piglet model., PMID:37530911
MicroRNA-127 promotes anti-microbial ability in porcine alveolar macrophages via S1PR3/TLR signaling pathway., PMID:37012029
Pectin supplement alleviates gut injury potentially through improving gut microbiota community in piglets., PMID:36569061
Co-fermented defatted rice bran alters gut microbiota and improves growth performance, antioxidant capacity, immune status and intestinal permeability of finishing pigs., PMID:36382202
Co-Cultures of Lactobacillus acidophilus and Bacillus subtilis Enhance Mucosal Barrier by Modulating Gut Microbiota-Derived Short-Chain Fatty Acids., PMID:36364738
Dietary high protein-induced diarrhea and intestinal inflammation by activation of NF-κB signaling in piglets., PMID:34738037
Low crude protein diets supplemented with casein hydrolysate enhance the intestinal barrier function and decrease the pro-inflammatory cytokine expression in the small intestine of pigs., PMID:34466681
Antiviral activity of portulaca oleracea L. extracts against porcine epidemic diarrhea virus by partial suppression on myd88/NF-κb activation in vitro., PMID:33781871
Reduced rotavirus vaccine efficacy in protein malnourished human-faecal-microbiota-transplanted gnotobiotic pig model is in part attributed to the gut microbiota., PMID:33245014
Effects of antimicrobial peptide cathelicidin-BF on diarrhea controlling, immune responses, intestinal inflammation and intestinal barrier function in piglets with postweaning diarrhea., PMID:32531710
Early-Life Intervention Using Fecal Microbiota Combined with Probiotics Promotes Gut Microbiota Maturation, Regulates Immune System Development, and Alleviates Weaning Stress in Piglets., PMID:31941102
Protective effect of chicken egg yolk immunoglobulins (IgY) against enterotoxigenic Escherichia coli K88 adhesion in weaned piglets., PMID:31286936
Analysis of interleukin-20 receptor complexes in trabecular meshwork cells and effects of cytokine signaling in anterior segment perfusion culture., PMID:31205408
Protecting intestinal epithelial cells against deoxynivalenol and E. coli damage by recombinant porcine IL-22., PMID:30955803
Tryptophan (Trp) modulates gut homeostasis via aryl hydrocarbon receptor (AhR)., PMID:30924357
Effects of dietary gamma-aminobutyric acid supplementation on the intestinal functions in weaning piglets., PMID:30601517
Nonclinical safety assessment of a human interleukin-22FC IG fusion protein demonstrates in vitro to in vivo and cross-species translatability., PMID:30464842
Beneficial effects of Saccharomyces cerevisiae RC016 in weaned piglets: in vivo and ex vivo analysis., PMID:30274522
Ultrasound targeting of Q-starch/miR-197 complexes for topical treatment of psoriasis., PMID:29870766
Effects of Lactobacillus reuteri LR1 on the growth performance, intestinal morphology, and intestinal barrier function in weaned pigs., PMID:29659876
Intramuscular vaccination of guinea pigs with the live-attenuated human herpes simplex vaccine VC2 stimulates a transcriptional profile of vaginal Th17 and regulatory Tr1 responses., PMID:29655629
Astilbin emulsion improves guinea pig lesions in a psoriasis-like model by suppressing IL-6 and IL-22 via p38 MAPK., PMID:29286161
Intestinal toxicity of deoxynivalenol is limited by Lactobacillus rhamnosus RC007 in pig jejunum explants., PMID:28993953
Oral Administration of Lactobacillus rhamnosus GG Ameliorates Salmonella Infantis-Induced Inflammation in a Pig Model via Activation of the IL-22BP/IL-22/STAT3 Pathway., PMID:28770173
IL-22 suppresses the infection of porcine enteric coronaviruses and rotavirus by activating STAT3 signal pathway., PMID:28322925
Seaweed extracts and galacto-oligosaccharides improve intestinal health in pigs following Salmonella Typhimurium challenge., PMID:28190419
Co-exposure to low doses of the food contaminants deoxynivalenol and nivalenol has a synergistic inflammatory effect on intestinal explants., PMID:27915442
Influence of orally fed a select mixture of Bacillus probiotics on intestinal T-cell migration in weaned MUC4 resistant pigs following Escherichia coli challenge., PMID:27424033
High therapeutic efficacy of Cathelicidin-WA against postweaning diarrhea via inhibiting inflammation and enhancing epithelial barrier in the intestine., PMID:27181680
Developmental expression of STATs, nuclear factor-κB and inflammatory genes in the jejunum of piglets during weaning., PMID:27160867
F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response., PMID:26490738
Cathelicidin-BF suppresses intestinal inflammation by inhibiting the nuclear factor-κB signaling pathway and enhancing the phagocytosis of immune cells via STAT-1 in weanling piglets., PMID:26044347
Effects of dietary supplementation with Laminaria hyperborea, Laminaria digitata, and Saccharomyces cerevisiae on the IL-17 pathway in the porcine colon., PMID:23365350
Deoxynivalenol as a new factor in the persistence of intestinal inflammatory diseases: an emerging hypothesis through possible modulation of Th17-mediated response., PMID:23326479
IL-22 is expressed by the invasive trophoblast of the equine (Equus caballus) chorionic girdle., PMID:22490443
Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation., PMID:21677670
Interleukin-22 and its crystal structure., PMID:17027512