Catalog No.
PHC39701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MMP10 (Tyr18-Cys476).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
MMP10,Matrix metalloproteinase-10,SL-2,MMP-10,Stromelysin-2,STMY2,Transin-2
Purification
Purified by antigen affinity column.
Accession
P09238
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Tezepelumab Efficacy in Patients with Severe, Uncontrolled Asthma with Comorbid Nasal Polyps in NAVIGATOR., PMID:37692126
Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19., PMID:35479098
Silica Induction of Diverse Inflammatory Proteome in Lungs of Lupus-Prone Mice Quelled by Dietary Docosahexaenoic Acid Supplementation., PMID:35126352
Elevated MMP10/13 mediated barrier disruption and NF-κB activation aggravate colitis and colon tumorigenesis in both individual or full miR-148/152 family knockout mice., PMID:34979166
Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview., PMID:34936194
Granulocyte-macrophage colony-stimulating factor initiates amniotic membrane rupture and preterm birth in a mouse model., PMID:33772943
A proteomic approach towards understanding the pathogenesis of Mooren's ulcer., PMID:33647271
Matrix metalloproteinases and their inhibitors in Fuchs endothelial corneal dystrophy., PMID:33617849
Identification of in vitro and in vivo oncolytic effect in colorectal cancer cells by Orf virus strain NA1/11., PMID:33416161
Expression of Matrix Metalloproteinases and Their Inhibitors in Endometrium: High Levels in Endometriotic Lesions., PMID:32325785
A Role for MMP-10 (Matrix Metalloproteinase-10) in Calcific Aortic Valve Stenosis., PMID:32188274
Elevated circulating metalloproteinase 7 predicts recurrent cardiovascular events in patients with carotid stenosis: a prospective cohort study., PMID:32101136
Selective inhibition of matrix metalloproteinase 10 (MMP10) with a single-domain antibody., PMID:31953328
Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90+ (myo-)fibroblasts in Crohn's disease and regulate Th1/Th17 cell responses., PMID:31633754
Novel specific human and mouse stromelysin-1 (MMP-3) and stromelysin-2 (MMP-10) antibodies for biochemical and immunohistochemical analyses., PMID:30761682
Monocytes accumulate in the airways of children with fatal asthma., PMID:30184280
Aberrant plasma MMP and TIMP dynamics in Schistosoma - Immune reconstitution inflammatory syndrome (IRIS)., PMID:30089120
The Matrix Metalloproteinases Panel in Multiple Sclerosis Patients Treated with Natalizumab: A Possible Answer to Natalizumab Non- Responders., PMID:29968546
Protein microarray analysis identifies key cytokines associated with malignant middle cerebral artery infarction., PMID:28828208
Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis., PMID:28805015
New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator., PMID:28379489
Profile of upregulated inflammatory proteins in sera of Myasthenia Gravis patients., PMID:28045063
Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study., PMID:27211902
Non-canonical role of matrix metalloprotease (MMP) in activation and migration of hepatic stellate cells (HSCs)., PMID:27140333
Identification of cytokines for early prediction of malignant middle cerebral artery infarction., PMID:26981614
Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis., PMID:26922382
Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a(-/-) mice., PMID:26558156
Expression of Matrix Metalloproteinase-10 at Invasive Front of Squamous Cell Carcinoma and Verrucous Carcinoma in the Oral Cavity., PMID:26434883
Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion., PMID:25978399
MMP-1 and Pro-MMP-10 as potential urinary pharmacodynamic biomarkers of FGFR3-targeted therapy in patients with bladder cancer., PMID:25326231
Simultaneous study of matrix metalloproteinases, proinflammatory cytokines, and soluble cytokine receptors in the tears of noninfectious corneal ulcer patients., PMID:25005620
Metastasis via Peritumoral Lymphatic Dilation in Oral Squamous Cell Carcinoma., PMID:27489817
Lack of clinical manifestations in asymptomatic dengue infection is attributed to broad down-regulation and selective up-regulation of host defence response genes., PMID:24727912
Chrysin inhibits metastatic potential of human triple-negative breast cancer cells by modulating matrix metalloproteinase-10, epithelial to mesenchymal transition, and PI3K/Akt signaling pathway., PMID:24122885
Marked induction of matrix metalloproteinase-10 by respiratory syncytial virus infection in human nasal epithelial cells., PMID:24009192
Matrix metalloproteinase levels in early HIV infection and relation to in vivo brain status., PMID:23979706
Tumor necrosis factor-α induces matrix metalloproteinases-3, -10, and -13 in human periodontal ligament cells., PMID:23688099
Stimulation of matrix metalloproteinases by tumor necrosis factor-α in human pulp cell cultures., PMID:23683281
Toll-like receptor activation and mechanical force stimulation promote the secretion of matrix metalloproteinases 1, 3 and 10 of human periodontal fibroblasts via p38, JNK and NF-kB., PMID:23332208
PAR2-induced inflammatory responses in human kidney tubular epithelial cells., PMID:23283995
Antioxidized LDL antibodies are associated with different metabolic pathways in patients with atherosclerotic plaque and type 2 diabetes., PMID:23193212
Matrix metalloproteinases, tissue inhibitors of matrix metalloproteinases, and inflammation in cyclosporine A-induced gingival enlargement: a pilot in vitro study using a three-dimensional model of the human oral mucosa., PMID:22934840
Synergistic effect of thrombin and CD40 ligand on endothelial matrix metalloproteinase-10 expression and microparticle generation in vitro and in vivo., PMID:22492089
Alterations of plasma inflammatory biomarkers in the healthy and chronic obstructive pulmonary disease patients with or without acute exacerbation., PMID:22343073
Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10., PMID:22285823
CRP promotes MMP-10 expression via c-Raf/MEK/ERK and JAK1/ERK pathways in cardiomyocytes., PMID:22142512
Biochemical properties of the matrix metalloproteinase NtMMP1 from Nicotiana tabacum cv. BY-2 suspension cells., PMID:20635096
Type-specific dysregulation of matrix metalloproteinases and their tissue inhibitors in end-stage heart failure patients: relationship between MMP-10 and LV remodelling., PMID:20219015
Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression., PMID:20064247
Conjunctival interleukin-13 expression in mucous membrane pemphigoid and functional effects of interleukin-13 on conjunctival fibroblasts in vitro., PMID:19910508
For research use only. Not for human or drug use.
