Catalog No.
PHC35501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CYP21A2 (Leu107-Gly390).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CYP21,CYP21B,Cytochrome P450 21,Cytochrome P450-C21B,Cytochrome P450-C21,Cytochrome P450 XXI,21-OHase,Steroid 21-hydroxylase,Cytochrome P-450c21,CYP21A2
Purification
Purified by antigen affinity column.
Accession
P08686
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Diagnostic Value of Autoantibodies against Steroidogenic Enzymes and Hormones in Infertile Women with Premature Ovarian Insufficiency., PMID:38928251
Relation between HLA and copy number variation of steroid 21-hydroxylase in a Swedish cohort of patients with autoimmune Addison's disease., PMID:37553728
The effect of etanercept therapy on adrenal steroid metabolism in juvenile idiopathic arthritis: a steroid metabolomics approach., PMID:37046333
The natural history of 21-hydroxylase autoantibodies in autoimmune Addison's disease., PMID:34665570
Measurement of serum tenascin-X in patients with congenital adrenal hyperplasia at risk for Ehlers-Danlos contiguous gene deletion syndrome CAH-X., PMID:31666125
Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison's Disease)., PMID:26618927
Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis., PMID:26515592
Secondary amenorrhoea associated with high serum 17-hydroxyprogesterone levels revealing a heterozygous CYP21A2 mutation in a woman with Addison disease., PMID:25353971
ACTH receptor blockade: a novel approach to treat congenital adrenal hyperplasia, or Cushing's disease., PMID:19931309
An investigation of the C4 gene arrangement in ethnic Chinese (Taiwanese)., PMID:18680512
Epitope mapping of human CYP1A2 in dihydralazine-induced autoimmune hepatitis., PMID:9241657
Tienilic acid-induced autoimmune hepatitis: anti-liver and-kidney microsomal type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9., PMID:8700140
For research use only. Not for human or drug use.
