Catalog No.
YHK57101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys58-Glu406
Predicted molecular weight
42.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NZN4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EH domain-containing protein 2, PAST2, PAST homolog 2, EHD2
Plasma membrane remodeling determines adipocyte expansion and mechanical adaptability., PMID:39609408
The missing link: ARID1B non-truncating variants causing Coffin-Siris syndrome due to protein aggregation., PMID:39028335
OsCOL5 suppresses heading through modulation of Ghd7 and Ehd2, enhancing rice yield., PMID:38884792
The adaptable caveola coat generates a plasma membrane sensory system., PMID:38788266
EH domain-containing protein 2 (EHD2): Overview, biological function, and therapeutic potential., PMID:38613224
EHD2, a novel HIF target gene, is a promising biomarker in clear cell renal cell carcinoma., PMID:38059172
EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events., PMID:37703099
Exogenous abscisic acid represses rice flowering via SAPK8-ABF1-Ehd1/Ehd2 pathway., PMID:37399924
Physical Training vs. Perindopril Treatment on Arterial Stiffening of Spontaneously Hypertensive Rats: A Proteomic Analysis and Possible Mechanisms., PMID:37239052
Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis., PMID:37122019
Differential haplotype expression in class I MHC genes during SARS-CoV-2 infection of human lung cell lines., PMID:36818472
A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome., PMID:36776558
Dynamin2 functions as an accessory protein to reduce the rate of caveola internalization., PMID:36729022
EHD2 overexpression promotes tumorigenesis and metastasis in triple-negative breast cancer by regulating store-operated calcium entry., PMID:36625722
Novel MYCBP::EHD2 and RUNX1::ZNF780A Fusion Genes in T-cell Acute Lymphoblastic Leukemia., PMID:36581344
The molecular organization of differentially curved caveolae indicates bendable structural units at the plasma membrane., PMID:36433988
Preliminary Extracellular Vesicle Profiling in Drainage Fluid After Neck Dissection in OSCC., PMID:36331313
qHD5 encodes an AP2 factor that suppresses rice heading by down-regulating Ehd2 expression., PMID:36041562
EHD2 inhibits the invasive ability of lung adenocarcinoma and improves the prognosis of patients., PMID:35928621
Super-resolution analysis of PACSIN2 and EHD2 at caveolae., PMID:35834519
GlycoTAIL and FlexiTAIL as Half-Life Extension Modules for Recombinant Antibody Fragments., PMID:35630749
Differential requirements for the Eps15 homology domain proteins EHD4 and EHD2 in the regulation of mammalian ciliogenesis., PMID:35510564
The eIg technology to generate Ig-like bispecific antibodies., PMID:35427197
Circular RNA Eps15-homology domain-containing protein 2 induce resistance of renal cell carcinoma to sunitinib via microRNA-4731-5p/ABCF2 axis., PMID:35412955
Circular RNA Eps15-homology domain containing protein 2 motivates proliferation, glycolysis but refrains autophagy in non-small cell lung cancer via crosstalk with microRNA-3186-3p and forkhead box K1., PMID:35220908
Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer., PMID:35177645
Bioorthogonal Conjugation-Assisted Purification Method for Profiling Cell Surface Proteome., PMID:35019258
EHD2 modulates Dll4 endocytosis during blood vessel development., PMID:34820962
Lysine acetylation regulates the interaction between proteins and membranes., PMID:34753925
Lung proteomic biomarkers associated with chronic obstructive pulmonary disease., PMID:34668408
EH Domain-Containing 2 Deficiency Restricts Adipose Tissue Expansion and Impairs Lipolysis in Primary Inguinal Adipocytes., PMID:34630160
Mechanical stretching of cells and lipid nanoparticles for nucleic acid delivery., PMID:34563590
The ménage à trois of autophagy, lipid droplets and liver disease., PMID:33794741
Energy and Dynamics of Caveolae Trafficking., PMID:33692993
Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B., PMID:33520362
EHD2 Overexpression Suppresses the Proliferation, Migration, and Invasion in Human Colon Cancer., PMID:33356637
Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance Development., PMID:33324235
Total Platelet Transcriptomics and Its Network Analysis by RNA-Seq and miRNA-Seq and PCA Application in Essential Thrombocythaemia., PMID:33227791
Caveolin1 Tyrosine-14 Phosphorylation: Role in Cellular Responsiveness to Mechanical Cues., PMID:33089394
TUSC8 inhibits the development of osteosarcoma by sponging miR‑197‑3p and targeting EHD2., PMID:32945345
Structural basis for designing an array of engrailed homeodomains., PMID:32876058
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members., PMID:32826901
[Unsaturated fatty acid of Actinidia chinesis planch seed oil (kiwi fruit essence) inhibits growth and metastasis of transplanted tumor in lung adenocarcinoma mice by up-regulating EHD2 expression]., PMID:32727647
Tagging and Deleting of Endogenous Caveolar Components Using CRISPR/Cas9 Technology., PMID:32548827
Analysis of Protein and Lipid Interactions Using Liposome Co-sedimentation Assays., PMID:32548824
Membrane tension buffering by caveolae: a role in cancer?, PMID:32474691
EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma., PMID:32409676
Lipid accumulation controls the balance between surface connection and scission of caveolae., PMID:32364496
[Caveolae mechanotranduction: a new role for the EHD2 ATPase]., PMID:32228835
Age attenuates the T-type CaV 3.2-RyR axis in vascular smooth muscle., PMID:32187825