Catalog No.
YHB61001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys41-Asp211
Predicted molecular weight
21.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95319
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CELF-2, hNAPOR, Neuroblastoma apoptosis-related RNA-binding protein, CUGBP Elav-like family member 2, CUG-BP- and ETR-3-like factor 2, BRUNOL3, NAPOR, ETR3, CUGBP2, CUG triplet repeat RNA-binding protein 2, ETR-3, CELF2, ELAV-type RNA-binding protein 3, RNA-binding protein BRUNOL-3, Bruno-like protein 3, CUG-BP2
Stepwise single-cell data identifies RNA binding proteins associated with the development of head and neck cancer and tumor microenvironment remodeling., PMID:40171814
CELF2 inhibits bladder cancer progression by decreasing the stability of CXCL5., PMID:40154776
Modeling epilepsy by loss-of-function of the CUG-binding protein Elav-like family member 2 in zebrafish with multi-omics analysis., PMID:40066778
EZH2 modulates mRNA splicing and exerts part of its oncogenic function through repression of splicing factors in CML., PMID:39774797
CELF2 promotes tau exon 10 inclusion via hinge domain-mediated nuclear condensation., PMID:39553957
RNA binding protein CUGBP2/ETR-3 regulates STAT3 alternative splicing., PMID:39550869
LINC01432 binds to CELF2 in newly diagnosed multiple myeloma promoting short progression-free survival to standard therapy., PMID:39483883
LINC01432 binds to CELF2 in newly diagnosed multiple myeloma promoting short progression-free survival to standard therapy., PMID:38979159
Loss of CELF2 promotes skin tumorigenesis and increases drug resistance., PMID:38887832
CELF2 Deficiency Demonstrates Autism-Like Behaviors and Interferes with Late Development of Cortical Neurons in Mice., PMID:38829512
The role of CELF family in neurodevelopment and neurodevelopmental disorders., PMID:38729272
miR-208a-3p regulated by circUQCRC2 suppresses ischemia/reperfusion-induced acute kidney injury by inhibiting CELF2-mediated tubular epithelial cell apoptosis, inflammation and ferroptosis., PMID:38664873
Loss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC1., PMID:38514854
Downregulated antisense lncRNA ENTPD3-AS1 contributes to the development of lung adenocarcinoma., PMID:38455397
Generation and characterization of a human iPSC line and gene-corrected isogenic line derived from a patient with a CELF2 gene mutation., PMID:38364506
Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome., PMID:38030819
CELF2 Sustains a Proliferating/OLIG2+ Glioblastoma Cell Phenotype via the Epigenetic Repression of SOX3., PMID:37894405
Comprehensive analysis of lncRNA-miRNA-mRNA ceRNA network and key genes in granulosa cells of patients with biochemical primary ovarian insufficiency., PMID:37847421
Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review)., PMID:37594127
Members of the CUGBP Elav-like family of RNA-binding proteins are expressed in distinct populations of primary sensory neurons., PMID:37537886
Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA., PMID:36973749
Alternative splicing of HDAC7 regulates its interaction with 14-3-3 proteins to alter histone marks and target gene expression., PMID:36933216
A Combination of Bio-Orthogonal Supramolecular Clicking and Proximity Chemical Tagging as a Supramolecular Tool for Discovery of Putative Proteins Associated with Laminopathic Disease., PMID:36843266
Role of SNPs located in the exon 9 of ATAPA1 gene on goose egg production., PMID:36774712
M2 macrophage-derived exosomal miR-1911-5p promotes cell migration and invasion in lung adenocarcinoma by down-regulating CELF2 -activated ZBTB4 expression., PMID:36730375
MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer., PMID:36727289
Retraction Note: GAS5 knockdown alleviates spinal cord injury by reducing VAV1 expression via RNA binding protein CELF2., PMID:36539521
Natural Antisense Long Noncoding RNA HHIP-AS1 Suppresses Non-Small-Cell Lung Cancer Progression by Increasing HHIP Stability via Interaction with CELF2., PMID:36374812
Exosomal miR-625-3p secreted by cancer-associated fibroblasts in colorectal cancer promotes EMT and chemotherapeutic resistance by blocking the CELF2/WWOX pathway., PMID:36336217
Construction of MicroRNA-Target Interaction Networks Based on MicroRNA Expression Profiles of HRV16-infected H1-HeLa Cells., PMID:36190000
CircLIFR Inhibits Non-small Cell Lung Cancer Progression by Acting as a miR-429 Sponge to Enhance CELF2 Expression., PMID:36104590
MiR-210-3p targets CELF2 to facilitate progression of lung squamous carcinoma through PI3K/AKT pathway., PMID:35972577
ELK1-Induced upregulation of long non-coding TNK2-AS1 promotes the progression of acute myeloid leukemia by EZH2-mediated epigenetic silencing of CELF2., PMID:35941836
Downregulation of STAT3 in Epstein-Barr Virus-Positive Hodgkin Lymphoma., PMID:35884913
MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy., PMID:35767654
Screening for Immune-Related RNA Biomarkers of Aneurysmal Subarachnoid Hemorrhage., PMID:35752978
Methylated DNA markers for plasma detection of ovarian cancer: Discovery, validation, and clinical feasibility., PMID:35370009
Network Theoretical Approach to Explore Factors Affecting Signal Propagation and Stability in Dementia's Protein-Protein Interaction Network., PMID:35327643
Erratum: RNA-binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1., PMID:35222722
Prognostic Significance of Alternative Splicing Genes in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma., PMID:34785939
miR-363-3p induces EMT via the Wnt/β-catenin pathway in glioma cells by targeting CELF2., PMID:34636136
CircPTK2 inhibits the tumorigenesis and metastasis of gastric cancer by sponging miR-134-5p and activating CELF2/PTEN signaling., PMID:34562827
A novel 13 RNA binding proteins (RBPs) signature could predict prostate cancer biochemical recurrence., PMID:34419719
LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression., PMID:34358519
CELF2 is a candidate prognostic and immunotherapy biomarker in triple-negative breast cancer and lung squamous cell carcinoma: A pan-cancer analysis., PMID:34288370
RNA-binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1., PMID:34257711
Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates., PMID:34107259
Prognostic biomarker identification and tumor classification in breast cancer patients by methylation and transcriptome analysis., PMID:34056873
Development and validation of a RNA binding protein-associated prognostic model for head and neck squamous cell carcinoma., PMID:33758106
Triclosan regulates alternative splicing events of nerve-related genes through RNA-binding protein CELF2 to induce zebrafish neurotoxicity., PMID:33621777
For research use only. Not for human or drug use.
