Catalog No.
YHK56601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn710-Ala890
Predicted molecular weight
22.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8NDT2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HuOTT3, RBM15B, One-twenty two protein 3, OTT3, RNA-binding motif protein 15B, HsOTT3, Putative RNA-binding protein 15B
RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors., PMID:40483690
LncRNA FOXD3-AS1 modulates ER stress and epithelial barrier dysfunction in allergic rhinitis by destabilizing CHOP mRNA., PMID:40081548
PSMD14 Transcriptionally Activated by MEF2A Promotes Pancreatic Cancer Development by Upregulating SPON2 Expression., PMID:40066751
RBM15B Promotes Prostate Cancer Cell Proliferation via PCNA m6A Modification., PMID:39361104
TARGET based m6A methylation-related genes predict prognosis relapsed B-cell acute lymphoblastic leukemia., PMID:39251964
Expression patterns and clinical value of key m6A RNA modification regulators in smoking patients with coronary artery disease., PMID:39167728
RNA binding protein RALY facilitates colorectal cancer metastasis via enhancing exosome biogenesis in m6A dependent manner., PMID:38880454
XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression., PMID:38740827
NME6 as a potential biomarker and therapeutic target involved in immune infiltration for lung adenocarcinoma., PMID:38517815
Identification of significant m6A regulators and immune microenvironment characterization in ischemic stroke., PMID:38342932
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation., PMID:38065948
Key m6A regulators mediated methylation modification pattern and immune infiltration characterization in hepatic ischemia-reperfusion injury., PMID:38049811
Identification and validation of m6A RNA regulatory network in pulpitis., PMID:37978362
Microenvironment modulation by key regulators of RNA N6-methyladenosine modification in respiratory allergic diseases., PMID:37328853
N 6-methyladenosine modification contributes to respiratory syncytial virus infection., PMID:37089388
Bioinformatics identification and experimental validation of m6A-related diagnostic biomarkers in the subtype classification of blood monocytes from postmenopausal osteoporosis patients., PMID:36967763
N6-methylation of RNA-bound adenosine regulator HNRNPC promotes vascular endothelial dysfunction in type 2 diabetes mellitus by activating the PSEN1-mediated Notch pathway., PMID:36681355
Diagnostic signature, subtype classification, and immune infiltration of key m6A regulators in osteomyelitis patients., PMID:36544487
Study on the prognosis, immune and drug resistance of m6A-related genes in lung cancer., PMID:36261786
Alterations of m6A RNA methylation regulators contribute to autophagy and immune infiltration in primary Sjögren's syndrome., PMID:36203590
Identification of clinical prognostic features of esophageal cancer based on m6A regulators., PMID:36159855
Unveiling the m6A Methylation Regulator Links between Prostate Cancer and Periodontitis by Transcriptomic Analysis., PMID:36133437
Prognostic value of comprehensive typing based on m6A and gene cluster in TNBC., PMID:36109402
Role of the N6-methyladenosine regulatory factor in reducing the risk of cardiovascular disease: subtype diagnosis following aerobic exercise-assisted weight loss., PMID:36105062
Comprehensive characterization of tumor microenvironment and m6A RNA methylation regulators and its effects on PD-L1 and immune infiltrates in cervical cancer., PMID:36091006
Gene signature of m6A-related targets to predict prognosis and immunotherapy response in ovarian cancer., PMID:36048273
N6-Methyladenosine regulator RBM15B acts as an independent prognostic biomarker and its clinical significance in uveal melanoma., PMID:36003405
m6A regulator-mediated RNA methylation modification patterns and immune microenvironment infiltration characterization in patients with intracranial aneurysms., PMID:35989938
RAB39B as a Chemosensitivity-Related Biomarker for Diffuse Large B-Cell Lymphoma., PMID:35910358
YY1-Targeted RBM15B Promotes Hepatocellular Carcinoma Cell Proliferation and Sorafenib Resistance by Promoting TRAM2 Expression in an m6A-Dependent Manner., PMID:35494016
Integrated Bioinformatic Analysis Identifies TIPIN as a Prognostic Biomarker in Hepatocellular Carcinoma., PMID:35082931
m6A regulator expression profile predicts the prognosis, benefit of adjuvant chemotherapy, and response to anti-PD-1 immunotherapy in patients with small-cell lung cancer., PMID:34802443
Human m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease., PMID:34650160
Comprehensive Analysis of Splicing Factor and Alternative Splicing Event to Construct Subtype-Specific Prognosis-Predicting Models for Breast Cancer., PMID:34630526
m6A Pathway Regulators Are Frequently Mutated in Breast Invasive Carcinoma and May Play an Important Role in Disease Pathogenesis., PMID:34520276
Effects of m6A RNA methylation regulators on endometrial cancer., PMID:34347888
Clinicopathological and immunological characterization of RNA m6 A methylation regulators in ovarian cancer., PMID:33225598
Altered Expression of the m6A Methyltransferase METTL3 in Alzheimer's Disease., PMID:32847866
The Expression of Cold-Inducible RNA-Binding Protein mRNA in Sow Genital Tract Is Modulated by Natural Mating, But Not by Seminal Plasma., PMID:32727091
Next-generation sequencing-based genomic profiling analysis reveals novel mutations for clinical diagnosis in Chinese primary epithelial ovarian cancer patients., PMID:30786925
BAP1 expression is prognostic in breast and uveal melanoma but not colon cancer and is highly positively correlated with RBM15B and USP19., PMID:30716094
m(6)A RNA methylation promotes XIST-mediated transcriptional repression., PMID:27602518
The RNA binding motif protein 15B (RBM15B/OTT3) is a functional competitor of serine-arginine (SR) proteins and antagonizes the positive effect of the CDK11p110-cyclin L2α complex on splicing., PMID:21044963
Requirement of UAP56, URH49, RBM15, and OTT3 in the expression of Kaposi sarcoma-associated herpesvirus ORF57., PMID:20828777
Nuclear export factor RBM15 facilitates the access of DBP5 to mRNA., PMID:19786495
The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1., PMID:19586903
For research use only. Not for human or drug use.
