Catalog No.
YHK55901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg251-Thr441
Predicted molecular weight
23.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UBF9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYOT, 57 kDa cytoskeletal protein, TTID, Titin immunoglobulin domain protein, Myotilin, Myofibrillar titin-like Ig domains protein
The Human Myometrial Transcriptome and the DNA Methylome of Testosterone-treated Patients Resemble the Myometria from Fibroid Patients., PMID:40474053
Evaluation of aggrephagy markers in myofibrillar myopathies., PMID:40413523
Mutational and clinical spectrum of myofibrillar myopathy in one center from China., PMID:39973468
The m6A modification regulates the composition of myofiber types in chicken skeletal muscle., PMID:39919566
Doxorubicin and topotecan resistance in ovarian cancer: Gene expression and microenvironment analysis in 2D and 3D models., PMID:39787968
Myotilin gene duplication causing late-onset myotilinopathy., PMID:39757377
Exploration of the genetic influence of MYOT and MB genes on the plumage coloration of Muscovy ducks., PMID:38585635
Combined sequence and copy number analysis improves diagnosis of limb girdle and other myopathies., PMID:37688281
A novel in-frame deletion in MYOT causes an early adult onset distal myopathy., PMID:37553249
[The anti-inflammatory effect of electroacupuncture in mice with spinal cord injury and molecular mechanism based on transcriptome sequencing technology]., PMID:37518961
Human Mutated MYOT and CRYAB Genes Cause a Myopathic Phenotype in Zebrafish., PMID:37511242
Silencing MYOT Expression May Inhibit Autophagy in Human Skeletal Muscle Cells., PMID:36776921
I536T variant of RBM20 affects splicing of cardiac structural proteins that are causative for developing dilated cardiomyopathy., PMID:36198914
One-Week Dynamic Changes in Cardiac Proteomes After Cardiac Radioablation in Experimental Rat Model., PMID:35837601
Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins., PMID:34480713
Molecular basis of F-actin regulation and sarcomere assembly via myotilin., PMID:33844684
Metformin rescues muscle function in BAG3 myofibrillar myopathy models., PMID:33030392
Mutations in PDLIM5 are rare in dilated cardiomyopathy but are emerging as potential disease modifiers., PMID:31880413
Transcriptional profiling of the murine intervertebral disc and age-associated changes in the nucleus pulposus., PMID:31597481
Identification of Transcriptional Signatures of Colon Tumor Stroma by a Meta-Analysis., PMID:31186640
Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk1., PMID:31094056
Childhood onset limb-girdle muscular dystrophies in the Aegean part of Turkey., PMID:30838351
Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines., PMID:30519347
Folding pathway of an Ig domain is conserved on and off the ribosome., PMID:30413621
Myofibrillar myopathy in the genomic context., PMID:30203143
Genetic Mutations and Demographic, Clinical, and Morphological Aspects of Myofibrillar Myopathy in a French Cohort., PMID:29924655
MicroRNA-17-3p promotes keratinocyte cells growth and metastasis via targeting MYOT and regulating Notch1/NF-κB pathways., PMID:29441982
Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains., PMID:28638118
Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines., PMID:28611294
Myofibrillar Myopathies: New Perspectives from Animal Models to Potential Therapeutic Approaches., PMID:28269794
Homozygosity of the Dominant Myotilin c.179C>T (p.Ser60Phe) Mutation Causes a More Severe and Proximal Muscular Dystrophy., PMID:27854214
Cardiac arrhythmia and late-onset muscle weakness caused by a myofibrillar myopathy with unusual histopathological features due to a novel missense mutation in FLNC., PMID:27633507
Mitochondrial dysfunction in myofibrillar myopathy., PMID:27618136
New aspects of myofibrillar myopathies., PMID:27389816
Rare variants in known and novel candidate genes predisposing to statin-associated myopathy., PMID:27296017
New insights into the protein aggregation pathology in myotilinopathy by combined proteomic and immunolocalization analyses., PMID:26842778
Analysis of the ACTN3 heterozygous genotype suggests that α-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion., PMID:26681802
Effect of Low-Magnitude, High-Frequency Vibration Treatment on Retardation of Sarcopenia: Senescence-Accelerated Mouse-P8 Model., PMID:26608404
Asparaginase-associated toxicity in children with acute lymphoblastic leukemia., PMID:26457414
Immunoblot as a potential diagnostic tool for myofibrillar myopathies., PMID:26383991
Myofibrillar myopathies: State of the art, present and future challenges., PMID:26342832
Mitochondrial abnormalities in the myofibrillar myopathies., PMID:26204918
Unusual multisystemic involvement and a novel BAG3 mutation revealed by NGS screening in a large cohort of myofibrillar myopathies., PMID:25208129
Expression of myotilin during chicken development., PMID:25125173
Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton., PMID:24989798
Novel recessive myotilin mutation causes severe myofibrillar myopathy., PMID:24928145
RNAi-mediated Gene Silencing of Mutant Myotilin Improves Myopathy in LGMD1A Mice., PMID:24781192
Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy., PMID:24668811
Mitochondrial abnormalities in myofibrillar myopathies., PMID:24361111
[Myofibrillar myopaathy]., PMID:24291893
For research use only. Not for human or drug use.
