Catalog No.
YHA10501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu21-Arg148
Predicted molecular weight
17.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00401
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
N-WASP, WASL, Neural Wiskott-Aldrich syndrome protein
Chlamydia trachomatis TmeA promotes pedestal-like structure formation through N-WASP and TOCA-1 interactions., PMID:40231845
LINC01305 and LAD1 Co-Regulate CTTN and N-WASP Phosphorylation, Mediating Cytoskeletal Reorganization to Promote ESCC Metastasis., PMID:39835575
Nuclear N-WASP Induces Actin Polymerization in the Nucleus with Cortactin as an Essential Factor., PMID:39791760
Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion., PMID:39487253
Tristetraprolin affects invasion-associated genes expression and cell motility in triple-negative breast cancer model., PMID:39319680
Predictive value analysis of the interaction network of Tks4 scaffold protein in colon cancer., PMID:39234565
The Chlamydia pneumoniae effector SemD exploits its host's endocytic machinery by structural and functional mimicry., PMID:39181890
Sulforaphane suppresses bladder cancer metastasis via blocking actin nucleation-mediated pseudopodia formation., PMID:39084455
Polyglutamine binding protein 1 regulates neurite outgrowth through recruiting N-WASP., PMID:38971314
Intrinsic Disorder in the Host Proteins Entrapped in Rabies Virus Particles., PMID:38932209
SOX4 induces cytoskeleton remodeling and promotes cell motility via N-wasp/ARP2/3 pathway in colorectal cancer cells., PMID:38705228
Actin-nucleation promoting factor N-WASP influences alpha-synuclein condensates and pathology., PMID:38693139
Apical expansion of calvarial osteoblasts and suture patency is dependent on fibronectin cues., PMID:38602508
Neural Wiskott-Aldrich syndrome protein (N-WASP) promotes distant metastasis in pancreatic ductal adenocarcinoma via activation of LOXL2., PMID:38560567
IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF., PMID:38536816
PLD1 promotes spindle assembly and migration through regulating autophagy in mouse oocyte meiosis., PMID:38513669
N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters., PMID:38085658
Lymphocyte migration regulation related proteins in urine exosomes may serve as a potential biomarker for lung cancer diagnosis., PMID:37980468
miRNAs from Inflamed Gingiva Link Gene Signaling to Increased MET Expression., PMID:37822091
Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats., PMID:37752166
A comprehensive identification of potential molecular targets and small drugs candidate for melanoma cancer using bioinformatics and network-based screening approach., PMID:37534476
MAPK Is a Mutual Pathway Targeted by Anxiety-Related miRNAs, and E2F5 Is a Putative Target for Anxiolytic miRNAs., PMID:36979479
Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes., PMID:36883283
Apical expansion of calvarial osteoblasts and suture patency is dependent on graded fibronectin cues., PMID:36711975
Analysis of Multifactor-Driven Myopia Disease Modules to Guide Personalized Treatment and Drug Development., PMID:35586671
Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of Schistosoma japonicum., PMID:35351657
Identification of Hub Genes Related to Alzheimer's Disease and Major Depressive Disorder., PMID:34732058
FCHSD2 cooperates with CDC42 and N-WASP to regulate cell protrusion formation., PMID:34520816
Macrothrombocytopenia of Takenouchi-Kosaki syndrome is ameliorated by CDC42 specific- and lipidation inhibitors in MEG-01 cells., PMID:34504210
A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks., PMID:34504078
Analysis of the distribution and expression of some tumor invasiveness markers in palate squamous cell carcinomas., PMID:34171074
Intracellular artificial supramolecules based on de novo designed Y15 peptides., PMID:34099696
Compound heterozygous variants in Wiskott-Aldrich syndrome like (WASL) gene segregating in a family with early onset Parkinson's disease., PMID:33571872
Latent developmental potential to form limb-like skeletal structures in zebrafish., PMID:33545089
Chlamydia trachomatis TmeA Directly Activates N-WASP To Promote Actin Polymerization and Functions Synergistically with TarP during Invasion., PMID:33468693
The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion., PMID:32946535
TRPV4 activates the Cdc42/N-wasp pathway to promote glioblastoma invasion by altering cellular protrusions., PMID:32843668
miR-142-3p Reduces the Size, Migration, and Contractility of Endometrial and Endometriotic Stromal Cells by Targeting Integrin- and Rho GTPase-Related Pathways That Regulate Cytoskeletal Function., PMID:32824678
N-Wasp Regulates Oligodendrocyte Myelination., PMID:32601246
A hypothesis about the role of fetal hemoglobin in COVID-19., PMID:32570166
Loss of Wasl improves pancreatic cancer outcome., PMID:32434991
Phospho-proteomic discovery of novel signal transducers including thioredoxin-interacting protein as mediators of erythropoietin-dependent human erythropoiesis., PMID:32259549
The effects of the M2a macrophage-induced axonal regeneration of neurons by arginase 1., PMID:31994698
WASP family proteins regulate the mobility of the B cell receptor during signaling activation., PMID:31974357
Ste20-like Kinase-mediated Control of Actin Polymerization Is a New Mechanism for Thin Filament-associated Regulation of Airway Smooth Muscle Contraction., PMID:31913659
αII-spectrin controls calcium-regulated exocytosis in neuroendocrine chromaffin cells through neuronal Wiskott-Aldrich Syndrome protein interaction., PMID:31859439
Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1., PMID:31769754
N-WASP knockdown upregulates inflammatory cytokines expression in human gingival fibroblasts., PMID:31751919
Concerted regulation of actin polymerization during constitutive secretion by cortactin and PKD2., PMID:31727638
N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis., PMID:31668663
For research use only. Not for human or drug use.
