Catalog No.
YHK48201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr14-Gly202
Predicted molecular weight
23.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96PU8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
QKI, HqkI, HKQ, Hqk, Protein quaking
Biological function of RNA-binding proteins in myocardial infarction: a potential emerging therapeutic limelight., PMID:40413549
KHSRP promotes the malignant behavior and cisplatin resistance of bladder cancer cells through the CLASP2/MAPRE1 axis., PMID:40382315
QKI-induced circ_0001766 inhibits colorectal cancer progression and rapamycin resistance by miR-1203/PPP1R3C/mTOR/Myc axis., PMID:40263288
Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is altered in striated muscle diseases., PMID:40207498
BiFC and FACS-based CRISPR screening revealed that QKI promotes PABPN1 LLPS in colorectal cancer cells., PMID:40052530
CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11., PMID:39994725
Estradiol Promotes Endometriosis Progression Via the ERβ/QKI /circSMAD2 Axis., PMID:39980288
Upregulation of YY1 in M2 macrophages promotes secretion of exosomes containing hsa-circ-0000326 via super-enhancers to facilitate prostate cancer progression., PMID:39960585
Quaking RNA-Binding protein (QKI) mediates circular RNA biogenesis in Litopenaeus vannamei during WSSV infection., PMID:39921020
Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 Axis., PMID:39756830
N7-methyladenosine-induced SLC7A7 serves as a prognostic biomarker in pan-cancer and promotes CRC progression in colorectal cancer., PMID:39730571
RNA-binding protein quaking: a multifunctional regulator in tumour progression., PMID:39711373
circPRMT10 regulated by QKI hypermethylation attenuates lung tumorigenesis induced by tobacco carcinogen NNK., PMID:39694006
Alternative Splicing in the Heart: The Therapeutic Potential of Regulating the Regulators., PMID:39684734
Depletion of the RNA binding protein QKI and circular RNA dysregulation in T-cell acute lymphoblastic leukemia., PMID:39633556
Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA., PMID:39574693
MYB::QKI fusion-positive diffuse glioma of the cerebellum: A case report., PMID:39569742
Neutrophil-centric analysis of gastric cancer: prognostic modeling and molecular insights., PMID:39540948
The multifaceted role of quaking protein in neuropsychiatric disorders and tumor progression., PMID:39479357
MYB/MYBL1-altered gliomas frequently harbor truncations and non-productive fusions in the MYB and MYBL1 genes., PMID:39422766
An ancient competition for the conserved branchpoint sequence influences physiological and evolutionary outcomes in splicing., PMID:39416098
Targeting the Hippo pathway in Schwann cells ameliorates peripheral nerve degeneration via a polypharmacological mechanism., PMID:39384453
Association of single nucleotide polymorphisms and gene-environment interactions with major depressive disorder in Chinese., PMID:39315198
Mature microRNA-binding protein QKI suppresses extracellular microRNA let-7b release., PMID:39308343
The splicing factor QKI inhibits metastasis by modulating alternative splicing of E-Syt2 in papillary thyroid carcinoma., PMID:39306227
Transcriptomic Alterations in Spliceosome Components in Advanced Heart Failure: Status of Cardiac-Specific Alternative Splicing Factors., PMID:39273537
Hsa_circ_0000520 suppresses vasculogenic mimicry formation and metastasis in bladder cancer through Lin28a/PTEN/PI3K signaling., PMID:39237880
Gene expression and alternative splicing analysis in a large-scale Multiple Sclerosis study., PMID:39185521
Clinical characteristics and detection of MYB-QKI fusions in patients with angiocentric glioma., PMID:39098857
CircSlc17a5 controlled by VLDLR/QKI pathway regulated the choroidal angiogenesis., PMID:39069227
Isoform balance of the long noncoding RNA NEAT1 is regulated by the RNA-binding protein QKI, governs the glioma transcriptome, and impacts cell migration., PMID:39032650
The role of circHmbox1(3,4) in ferroptosis-mediated cognitive impairments induced by manganese., PMID:39024764
Clinicopathologic Significance of Quaking Expression in Hepatocellular Carcinoma., PMID:38936929
Circ6834 suppresses non-small cell lung cancer progression by destabilizing ANHAK and regulating miR-873-5p/TXNIP axis., PMID:38890620
Circular RNA Circ_0001322 inhibits gastric cancer progression by modulating the miR-1264/QKI axis and suppressing the Hedgehog pathway., PMID:38814217
RNA-binding protein QKI promotes the progression of HCC by interacting with long non-coding RNA EGOT., PMID:38810307
CircPKN2 promotes ferroptosis in bladder cancer by promoting the ubiquitination of Stearoyl-CoA Desaturase 1., PMID:38802550
GAS5 regulated by FTO-mediated m6A modification suppresses cell proliferation via the IGF2BP2/QKI axis in breast cancer., PMID:38782769
Involvement of circRNA Regulators MBNL1 and QKI in the Progression of Esophageal Squamous Cell Carcinoma., PMID:38769028
Epidemiologic association and shared genetic architecture between cataract and hearing difficulties among middle-aged and older adults., PMID:38632618
The RNA-binding protein quaking is upregulated in nitrofen-induced congenital diaphragmatic hernia lungs at the end of gestation., PMID:38472353
Comprehensive analysis of MYB/MYBL1-altered pediatric-type diffuse low-grade glioma., PMID:38466086
Downregulated antisense lncRNA ENTPD3-AS1 contributes to the development of lung adenocarcinoma., PMID:38455397
Mature microRNA-binding protein QKI promotes microRNA-mediated gene silencing., PMID:38372062
Hypoxia increases the biogenesis of IGF2BP3-bound circular RNAs., PMID:38329630
Clinicopathological analysis of BRAF and non-BRAF MAPK pathway-altered gliomas in paediatric and adult patients: a single-institution study of 40 patients., PMID:38195220
The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking., PMID:38112323
Non-adherent culture method affects the proliferation and apoptosis of mesenchymal stem cells through inhibiting LINC00707 to promote RNF6-mediated QKI ubiquitination., PMID:38072302
hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma., PMID:38044421
FOXP3-regulated lncRNA NONHSAT136151 promotes colorectal cancer progression by disrupting QKI interaction with target mRNAs., PMID:38041531
For research use only. Not for human or drug use.
