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Anti-UMOD Polyclonal Antibody

Catalog #:   PHC28401 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P07911
Overview

Catalog No.

PHC28401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human UMOD (Glu334-Ser589).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Tamm-Horsfall urinary glycoprotein,THP,Uromodulin,UMOD

Purification

Purified by antigen affinity column.

Accession

P07911

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with UMOD antibody (PHC28401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 31 kDa
    Observed MW: 31 kDa
References

The development of lateral flow devices for urinary biomarkers to assess kidney health., PMID:38609491

Development and nationwide validation of kidney graft injury markers using urinary exosomes and microvesicles (complete English translation of the Japanese version)., PMID:37280521

Integrated Bioinformatics Analysis for the Identification of Key lncRNAs, mRNAs, and Potential Drugs in Clear Cell Renal Cell Carcinomas., PMID:37275334

Tubular epithelial progenitors are excreted in urine during recovery from severe acute kidney injury and are able to expand and differentiate in vitro., PMID:36285332

Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases., PMID:35446786

Significance of kidney biopsy in autosomal dominant tubulointerstitial kidney disease-UMOD: is kidney biopsy truly nonspecific?, PMID:33397327

A Uromodulin Mutation Drives Autoimmunity and Kidney Mononuclear Phagocyte Endoplasmic Reticulum Stress., PMID:32926855

Serum uromodulin is associated with the severity of clinicopathological findings in ANCA-associated glomerulonephritis., PMID:31725735

[Uromodulin gene polymorphisms in patients with cast nephropathy in multiple myeloma]., PMID:28914853

Immunological Signatures after Bordetella pertussis Infection Demonstrate Importance of Pulmonary Innate Immune Cells., PMID:27711188

Paraprotein-Related Kidney Disease: Evaluation and Treatment of Myeloma Cast Nephropathy., PMID:27526708

A structured interdomain linker directs self-polymerization of human uromodulin., PMID:26811476

Treatment of acute kidney injury with cast nephropathy., PMID:24725380

Specificity, sensitivity, and operability of RSID™-urine for forensic identification of urine: comparison with ELISA for Tamm-Horsfall protein., PMID:22563762

Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model., PMID:22484815

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression., PMID:20172860

Proteomics and detection of uromodulin in first-time renal calculi patients and recurrent renal calculi patients., PMID:19145410

[Construction of urinary Tamm-Horsfall protein assay by enzyme-linked immunosorbent assay and establishment of reference range of healthy subject]., PMID:19068782

Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron., PMID:18753295

Use of dual section mRNA in situ hybridisation/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidney., PMID:18618131

Human renal cells from the thick ascending limb and early distal tubule: characterization of primary isolated and cultured cells by reverse transcription polymerase chain reaction., PMID:18331438

Progressive accumulation of intrinsic mouse uromodulin in the kidneys of transgenic mice harboring the mutant human uromodulin gene., PMID:18310901

Identification of the scavenger receptors SREC-I, Cla-1 (SR-BI), and SR-AI as cellular receptors for Tamm-Horsfall protein., PMID:17928461

Disappearance of tophi in familial juvenile hyperuricemic nephropathy after kidney transplantation., PMID:17868056

Characterization of a long-term rat mTAL cell line., PMID:17670898

Tamm-Horsfall protein in recurrent calcium kidney stone formers with positive family history: abnormalities in urinary excretion, molecular structure and function., PMID:17345077

Study of antibody production to Tamm-Horsfall protein in renal transplant donors and recipients., PMID:17181068

Immunological detection of nitrosative stress-mediated modified Tamm-Horsfall glycoprotein (THP) in calcium oxalate stone formers., PMID:16766391

Importance of carbohydrate in the interaction of Tamm-Horsfall protein with complement 1q and inhibition of classical complement activation., PMID:16594900

[Chronic pyelonephritis: Pathogenesis, pathophysiology, and therapy]., PMID:16523939

Methodological approaches to detection of Tamm-Horsfall protein., PMID:16307051

Problems with the estimation of urine protein by automated assays., PMID:15820780

Development of a new method for measuring total urinary protein using acid violet 6B pigment., PMID:12938142

[Laboratory identification and measurement of urinary proteins]., PMID:12368138

Salt-precipitation method does not isolate to homogeneity Tamm-Horsfall glycoprotein from urine of proteinuric patients and pregnant women., PMID:12270772

Vitamin A excreted in the urine of canines is associated with a Tamm-Horsfall like protein., PMID:12056481

Analysis of the C-terminal structure of urinary Tamm-Horsfall protein reveals that the release of the glycosyl phosphatidylinositol-anchored counterpart from the kidney occurs by phenylalanine-specific proteolysis., PMID:11741296

[Relationship between Syndrome-Type in TCM and four trace urinary proteins in patients with bronchial asthma]., PMID:11475730

Semiquantitative analysis of urinary low protein levels using silver dot blot assay., PMID:11436197

Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein., PMID:11337384

The sugar moiety of Tamm-Horsfall protein is affected by the carbohydrate-deficient glycoprotein type I syndrome. A case study., PMID:10815984

Antibodies to Tamm-Horsfall protein in endemic nephropathy., PMID:10534506

Errors in reported association between Tamm-Horsfall protein and IgG., PMID:10475789

Transdifferentiation of distal but not proximal tubular epithelial cells from human kidney in culture., PMID:10450018

Composition of the sugar moiety of Tamm-Horsfall protein in patients with urinary diseases., PMID:10436264

Alterations of the sugar moiety of Tamm-Horsfall protein in children with malignancies of lymphoid cells., PMID:10424459

The influence of ofloxacin (Tarivid) on the parasite-host inter-relationship in patients with chronic urinary tract infection., PMID:10394987

Binding of human neutrophils to cell-surface anchored Tamm-Horsfall glycoprotein in tubulointerstitial nephritis., PMID:10231441

Expression of TWIK-1, a novel weakly inward rectifying potassium channel in rat kidney., PMID:9843722

The co-localization of stanniocalcin protein, mRNA and kidney cell markers in the rat kidney., PMID:9771461

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-UMOD Polyclonal Antibody [PHC28401]
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