Catalog No.
PHC28401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human UMOD (Glu334-Ser589).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Tamm-Horsfall urinary glycoprotein,THP,Uromodulin,UMOD
Purification
Purified by antigen affinity column.
Accession
P07911
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The development of lateral flow devices for urinary biomarkers to assess kidney health., PMID:38609491
Development and nationwide validation of kidney graft injury markers using urinary exosomes and microvesicles (complete English translation of the Japanese version)., PMID:37280521
Integrated Bioinformatics Analysis for the Identification of Key lncRNAs, mRNAs, and Potential Drugs in Clear Cell Renal Cell Carcinomas., PMID:37275334
Tubular epithelial progenitors are excreted in urine during recovery from severe acute kidney injury and are able to expand and differentiate in vitro., PMID:36285332
Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases., PMID:35446786
Significance of kidney biopsy in autosomal dominant tubulointerstitial kidney disease-UMOD: is kidney biopsy truly nonspecific?, PMID:33397327
A Uromodulin Mutation Drives Autoimmunity and Kidney Mononuclear Phagocyte Endoplasmic Reticulum Stress., PMID:32926855
Serum uromodulin is associated with the severity of clinicopathological findings in ANCA-associated glomerulonephritis., PMID:31725735
[Uromodulin gene polymorphisms in patients with cast nephropathy in multiple myeloma]., PMID:28914853
Immunological Signatures after Bordetella pertussis Infection Demonstrate Importance of Pulmonary Innate Immune Cells., PMID:27711188
Paraprotein-Related Kidney Disease: Evaluation and Treatment of Myeloma Cast Nephropathy., PMID:27526708
A structured interdomain linker directs self-polymerization of human uromodulin., PMID:26811476
Treatment of acute kidney injury with cast nephropathy., PMID:24725380
Specificity, sensitivity, and operability of RSID™-urine for forensic identification of urine: comparison with ELISA for Tamm-Horsfall protein., PMID:22563762
Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model., PMID:22484815
Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression., PMID:20172860
Proteomics and detection of uromodulin in first-time renal calculi patients and recurrent renal calculi patients., PMID:19145410
[Construction of urinary Tamm-Horsfall protein assay by enzyme-linked immunosorbent assay and establishment of reference range of healthy subject]., PMID:19068782
Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron., PMID:18753295
Use of dual section mRNA in situ hybridisation/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidney., PMID:18618131
Human renal cells from the thick ascending limb and early distal tubule: characterization of primary isolated and cultured cells by reverse transcription polymerase chain reaction., PMID:18331438
Progressive accumulation of intrinsic mouse uromodulin in the kidneys of transgenic mice harboring the mutant human uromodulin gene., PMID:18310901
Identification of the scavenger receptors SREC-I, Cla-1 (SR-BI), and SR-AI as cellular receptors for Tamm-Horsfall protein., PMID:17928461
Disappearance of tophi in familial juvenile hyperuricemic nephropathy after kidney transplantation., PMID:17868056
Characterization of a long-term rat mTAL cell line., PMID:17670898
Tamm-Horsfall protein in recurrent calcium kidney stone formers with positive family history: abnormalities in urinary excretion, molecular structure and function., PMID:17345077
Study of antibody production to Tamm-Horsfall protein in renal transplant donors and recipients., PMID:17181068
Immunological detection of nitrosative stress-mediated modified Tamm-Horsfall glycoprotein (THP) in calcium oxalate stone formers., PMID:16766391
Importance of carbohydrate in the interaction of Tamm-Horsfall protein with complement 1q and inhibition of classical complement activation., PMID:16594900
[Chronic pyelonephritis: Pathogenesis, pathophysiology, and therapy]., PMID:16523939
Methodological approaches to detection of Tamm-Horsfall protein., PMID:16307051
Problems with the estimation of urine protein by automated assays., PMID:15820780
Development of a new method for measuring total urinary protein using acid violet 6B pigment., PMID:12938142
[Laboratory identification and measurement of urinary proteins]., PMID:12368138
Salt-precipitation method does not isolate to homogeneity Tamm-Horsfall glycoprotein from urine of proteinuric patients and pregnant women., PMID:12270772
Vitamin A excreted in the urine of canines is associated with a Tamm-Horsfall like protein., PMID:12056481
Analysis of the C-terminal structure of urinary Tamm-Horsfall protein reveals that the release of the glycosyl phosphatidylinositol-anchored counterpart from the kidney occurs by phenylalanine-specific proteolysis., PMID:11741296
[Relationship between Syndrome-Type in TCM and four trace urinary proteins in patients with bronchial asthma]., PMID:11475730
Semiquantitative analysis of urinary low protein levels using silver dot blot assay., PMID:11436197
Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein., PMID:11337384
The sugar moiety of Tamm-Horsfall protein is affected by the carbohydrate-deficient glycoprotein type I syndrome. A case study., PMID:10815984
Antibodies to Tamm-Horsfall protein in endemic nephropathy., PMID:10534506
Errors in reported association between Tamm-Horsfall protein and IgG., PMID:10475789
Transdifferentiation of distal but not proximal tubular epithelial cells from human kidney in culture., PMID:10450018
Composition of the sugar moiety of Tamm-Horsfall protein in patients with urinary diseases., PMID:10436264
Alterations of the sugar moiety of Tamm-Horsfall protein in children with malignancies of lymphoid cells., PMID:10424459
The influence of ofloxacin (Tarivid) on the parasite-host inter-relationship in patients with chronic urinary tract infection., PMID:10394987
Binding of human neutrophils to cell-surface anchored Tamm-Horsfall glycoprotein in tubulointerstitial nephritis., PMID:10231441
Expression of TWIK-1, a novel weakly inward rectifying potassium channel in rat kidney., PMID:9843722
The co-localization of stanniocalcin protein, mRNA and kidney cell markers in the rat kidney., PMID:9771461