Catalog No.
DHD10805
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15391
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
SGN-19A, SGN-CD19A, hBU12-491, unconjugated: huBU12, CAS: 1630074-14-4
Clone ID
Denintuzumab
Preclinical activity of the antibody-drug conjugate denintuzumab mafodotin (SGN-CD19A) against pediatric acute lymphoblastic leukemia xenografts, PMID: 31012549
New monoclonal antibodies for the treatment of acute lymphoblastic leukemia, PMID: 27521873
Monoclonal antibodies and immune therapies for adult precursor B-acute lymphoblastic leukemia, PMID: 26921100
Emerging antibody-drug conjugates for treating lymphoid malignancies, PMID: 28792782
Invasive Fungal Diseases in Children with Hematological Malignancies Treated with Therapies That Target Cell Surface Antigens: Monoclonal Antibodies, Immune Checkpoint Inhibitors and CAR T-Cell Therapies, PMID: 33807678
Invasive Fungal Diseases in Children with Hematological Malignancies Treated with Therapies That Target Cell Surface Antigens: Monoclonal Antibodies, Immune Checkpoint Inhibitors and CAR T-Cell Therapies., PMID:33807678
Preclinical activity of the antibody-drug conjugate denintuzumab mafodotin (SGN-CD19A) against pediatric acute lymphoblastic leukemia xenografts., PMID:31012549
Emerging antibody-drug conjugates for treating lymphoid malignancies., PMID:28792782
New monoclonal antibodies for the treatment of acute lymphoblastic leukemia., PMID:27521873
Monoclonal antibodies and immune therapies for adult precursor B-acute lymphoblastic leukemia., PMID:26921100
For research use only. Not for human or drug use.
