Catalog No.
YHK42001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val18-Asn205
Predicted molecular weight
23.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IW35
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cep97, Leucine-rich repeat and IQ domain-containing protein 2, LRRIQ2, CEP97, Centrosomal protein of 97 kDa
Disrupted glucocorticoid receptor cell signalling causes a ciliogenesis defect in the fetal mouse renal tubule., PMID:40247090
Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends., PMID:39847124
Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis., PMID:39819503
Permanent cilia loss during cerebellar granule cell neurogenesis involves withdrawal of cilia maintenance and centriole capping., PMID:39705308
Cep104 is a component of the centriole distal tip complex that regulates centriole growth and contributes to Drosophila spermiogenesis., PMID:37729913
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis., PMID:36790165
Genome-wide association studies of COVID-19: Connecting the dots., PMID:36280088
Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal end., PMID:35707992
A modified TurboID approach identifies tissue-specific centriolar components in C. elegans., PMID:35442950
Aggresome assembly at the centrosome is driven by CP110-CEP97-CEP290 and centriolar satellites., PMID:35411088
ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis., PMID:35301795
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole., PMID:34813648
CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis., PMID:34787650
Cep97 Is Required for Centriole Structural Integrity and Cilia Formation in Drosophila., PMID:32589908
KCTD10 Biology: An Adaptor for the Ubiquitin E3 Complex Meets Multiple Substrates: Emerging Divergent Roles of the cullin-3/KCTD10 E3 Ubiquitin Ligase Complex in Various Cell Lines., PMID:32484264
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation., PMID:30404837
M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole., PMID:30375385
LRRC45 contributes to early steps of axoneme extension., PMID:30131441
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome., PMID:29395072
Biophysical and Structural Characterization of the Centriolar Protein Cep104 Interaction Network., PMID:27402853
Asterless is required for centriole length control and sperm development., PMID:27185836
WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis., PMID:26675238
Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis., PMID:26670998
TTBK2: a tau protein kinase beyond tau phosphorylation., PMID:25950000
Centrin2 regulates CP110 removal in primary cilium formation., PMID:25753040
Binding to Cep164, but not EB1, is essential for centriolar localization of TTBK2 and its function in ciliogenesis., PMID:25297623
The nuclear pool of tetraspanin CD9 contributes to mitotic processes in human breast carcinoma., PMID:25103498
CEP120 and SPICE1 cooperate with CPAP in centriole elongation., PMID:23810536
The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis., PMID:23400999
A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins., PMID:22885064
Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture., PMID:22261722
Centriolar kinesin Kif24 interacts with CP110 to remodel microtubules and regulate ciliogenesis., PMID:21620453
Daughter centriole elongation is controlled by proteolysis., PMID:20861314
Chromosomal imbalances are uncommon in chagasic megaesophagus., PMID:20163722
Cep76, a centrosomal protein that specifically restrains centriole reduplication., PMID:19460342
Double life of centrioles: CP110 in the spotlight., PMID:18068367
Cep97 and CP110 suppress a cilia assembly program., PMID:17719545
For research use only. Not for human or drug use.
