Catalog No.
PHC22301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human KLK1 (Ile25-Asn261).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Kallikrein-1,Kidney/pancreas/salivary gland kallikrein,Tissue kallikrein,KLK1
Purification
Purified by antigen affinity column.
Accession
P06870
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Proteomic identification of elevated saliva kallikrein levels in the mdx-4cv mouse model of Duchenne muscular dystrophy., PMID:31193643
Increased fibrinolysis-induced bradykinin formation in hereditary angioedema confirmed using stored plasma and biotechnological inhibitors., PMID:31133046
Tissue kallikrein regulates alveolar macrophage apoptosis early in influenza virus infection., PMID:30908937
Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer., PMID:30114962
Tissue kallikrein-related peptidase 4 (KLK4), a novel biomarker in triple-negative breast cancer., PMID:28755528
Gene signatures related to HAI response following influenza A/H1N1 vaccine in older individuals., PMID:27441275
Kallikrein transduced mesenchymal stem cells protect against anti-GBM disease and lupus nephritis by ameliorating inflammation and oxidative stress., PMID:23935844
Copy number variants in the kallikrein gene cluster., PMID:23894413
Elevated immunoglobulin to tissue KLK11 in patients with Sjögren syndrome., PMID:23086370
Tickling stimulation causes the up-regulation of the kallikrein family in the submandibular gland of the rat., PMID:22982067
A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptor., PMID:19879874
Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases., PMID:19527222
Kallikreins and lupus nephritis., PMID:19348047
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans., PMID:19307730
The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis., PMID:19262577
Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3., PMID:19232384
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients., PMID:17518992
High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays., PMID:16510109
Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases., PMID:16086736
Autoimmunity against a tissue kallikrein in IQI/Jic Mice: a model for Sjogren's syndrome., PMID:15545270
Tissue kallikrein KLK1 is expressed de novo in endothelial cells and mediates relaxation of human umbilical veins., PMID:11727832
Multiplexed fluorescent bead-based immunoassays for quantitation of human cytokines in serum and culture supernatants., PMID:11598944
Kininogen expression by rat vascular smooth muscle cells: stimulation by lipopolysaccharide and angiotensin II., PMID:9739161
For research use only. Not for human or drug use.
