Anti-CRH Polyclonal Antibody

Catalog No.

PHC22001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CRH (His40-Gly195).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Corticoliberin,Corticotropin-releasing hormone,CRH,CRF,Corticotropin-releasing factor

Purification

Purified by antigen affinity column.

Accession

P06850

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Mast cells and corticotropin-releasing hormone receptors in duodenal tissue of children with functional dyspepsia., PMID:40050228

Hormone circuit explains why most HPA drugs fail for mood disorders and predicts the few that work., PMID:39849227

Antidepressant and anxiolytic effects of Wuling Capsule in CSDS mice: Alleviating HPA axis hyperactivity via the Nesfatin-1/NF-κB signaling pathway., PMID:39551280

High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer's disease., PMID:39358820

Single agent subcutaneous blinatumomab for advanced acute lymphoblastic leukemia., PMID:38317420

A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice., PMID:38241484

Human placenta releases extracellular vesicles carrying corticotrophin releasing hormone mRNA into the maternal blood., PMID:38190772

[Features of inflammatory reactions in patients with juvenile depression with a clinically high risk of psychosis]., PMID:38127701

Cerebrospinal fluid findings in patients with obsessive-compulsive disorder, Tourette syndrome, and PANDAS: A systematic literature review., PMID:37748568

Longitudinal efficacy and safety modeling and simulation framework to aid dose selection of belantamab mafodotin for patients with multiple myeloma., PMID:37465991

Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial., PMID:37187198

Congenital adrenal hyperplasia: New biomarkers and adult treatments., PMID:36842612

Real-world use of blinatumomab in adult patients with B-cell acute lymphoblastic leukemia in clinical practice: results from the NEUF study., PMID:36599847

Solid-state NMR of paired helical filaments formed by the core tau fragment tau(297-391)., PMID:36570831

How GRAIL controls Treg function to maintain self-tolerance., PMID:36569931

SARS-CoV-2 seroprevalence, cumulative infections, and immunity to symptomatic infection - A multistage national household survey and modelling study, Dominican Republic, June-October 2021., PMID:36408529

Full regeneration of descending corticotropin-releasing hormone axons after a complete spinal cord injury in lampreys., PMID:36320936

Immunologic aspects of migraine: A review of literature., PMID:36247795

Organization of the corticotropin-releasing hormone and corticotropin-releasing hormone-binding protein systems in the central nervous system of the sea lamprey Petromyzon marinus., PMID:36150899

Efficacy and safety of blinatumomab in Chinese adults with Ph-negative relapsed/refractory B-cell precursor acute lymphoblastic leukemia: A multicenter open-label single-arm China registrational study., PMID:36000952

Corticotropin releasing hormone as an identifier of bronchiolitis obliterans syndrome., PMID:35589861

GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner., PMID:35504998

The role of corticoliberin concentration levels and placental CRH receptors 1 and 2 in the prolongation of pregnancy., PMID:35475389

Impact of Blinatumomab Treatment on Bone Marrow Function in Patients with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia., PMID:34830762

Soporific effect of modified Suanzaoren Decoction on mice models of insomnia by regulating Orexin-A and HPA axis homeostasis., PMID:34509822

The ROR1 antibody-drug conjugate huXBR1-402-G5-PNU effectively targets ROR1+ leukemia., PMID:34424320

Postpartum maternal exposure to predator odor alters offspring antipredator behavior, basal HPA axis activity and immunoglobulin levels in adult Brandt's voles., PMID:34416302

Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial., PMID:34401888

Blinatumomab for HLA loss relapse after haploidentical hematopoietic stem cell transplantation., PMID:34249448

Stress and Nasal Allergy: Corticotropin-Releasing Hormone Stimulates Mast Cell Degranulation and Proliferation in Human Nasal Mucosa., PMID:33803422

[A Case of Thyroid Dysfunction and Isolated Adrenocorticotropin Deficiency after Nivolumab Therapy for Malignant Melanoma]., PMID:33678791

Long-term follow-up of blinatumomab in patients with relapsed/refractory Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukaemia: Final analysis of ALCANTARA study., PMID:33588145

Lymphocytic infundibuloneurohypophysitis with positive anti-rabphilin-3A antibodies nine years post-onset of central diabetes insipidus., PMID:33446956

Gene Expression Analysis of the Pre-Diabetic Pancreas to Identify Pathogenic Mechanisms and Biomarkers of Type 1 Diabetes., PMID:33424774

Repeated and single maternal separation specifically alter microglial morphology in the prefrontal cortex and neurogenesis in the hippocampus of 15-day-old male mice., PMID:33165192

Long-term survival of patients with relapsed/refractory acute lymphoblastic leukemia treated with blinatumomab., PMID:33141929

Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the line 66 model of frontotemporal dementia., PMID:33127647

Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia., PMID:32929488

Human virus detection with graphene-based materials., PMID:32750677

A Randomized Controlled Study to Evaluate the Safety and Reactogenicity of a Novel rVLP-Based Plant Virus Nanoparticle Adjuvant Combined with Seasonal Trivalent Influenza Vaccine Following Single Immunization in Healthy Adults 18-50 Years of Age., PMID:32698532

Restraint stress and elevation of corticotrophin-releasing hormone in female mice impair oocyte competence through activation of the tumour necrosis factor α (TNF-α) system., PMID:32527376

Brain control of humoral immune responses amenable to behavioural modulation., PMID:32405000

Phase 1b/2 study of blinatumomab in Japanese adults with relapsed/refractory acute lymphoblastic leukemia., PMID:31971321

Phase 3 Efficacy Trial of Modified Vaccinia Ankara as a Vaccine against Smallpox., PMID:31722150

Molecular response with blinatumomab in relapsed/refractory B-cell precursor acute lymphoblastic leukemia., PMID:31648325

Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma., PMID:31639039

Transplantation in adults with relapsed/refractory acute lymphoblastic leukemia who are treated with blinatumomab from a phase 3 study., PMID:31433496

Management of bleeding and invasive procedures in haemophilia A patients with inhibitor treated with emicizumab (Hemlibra® ): Proposals from the French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia, in collaboration with the French Working Group on Perioperative Haemostasis (GIHP)., PMID:31294904

Nivolumab-induced hypophysitis causing secondary adrenal insufficiency after transient ACTH elevation., PMID:31217401

Blinatumomab for Acute Lymphoblastic Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation., PMID:31002989

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