Catalog No.
YHK37801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr941-Pro1321
Predicted molecular weight
46.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y4C1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA0742, KDM3A, JMJD1, Jumonji domain-containing protein 1A, Lysine-specific demethylase 3A, [histone H3]-dimethyl-L-lysine(9) demethylase 3A, JmjC domain-containing histone demethylation protein 2A, TSGA, JHDM2A, JMJD1A
KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells., PMID:40510131
Maternal iron deficiency causes male-to-female sex reversal in mouse embryos., PMID:40468068
Lactobacillus paracasei Activates the KDM3A/VAMP1 Axis to Induce Autophagy in Renal Tubular Epithelial Cells in Chronic Kidney Disease., PMID:40111701
Comprehensive systems biology analysis of microRNA-101-3p regulatory network identifies crucial genes and pathways in hepatocellular carcinoma., PMID:40074445
CCDC134 enhances ovarian reserve function and angiogenesis by directly interacting with INHA in a mouse model of premature ovarian insufficiency., PMID:40042746
KDM3A controls postnatal hippocampal neurogenesis via dual regulation of the Wnt/β-catenin signaling pathway., PMID:40033066
ABCF1-K430-Lactylation promotes HCC malignant progression via transcriptional activation of HIF1 signaling pathway., PMID:39753865
Impact of Hypoxia and the Levels of Transcription Factor HIF-1α and JMJD1A on Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma Cell Lines., PMID:39467631
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma., PMID:39448867
Application of large-scale and multicohort plasma proteomics data to discover novel causal proteins in gastric cancer., PMID:39422802
Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling., PMID:39281802
Histone H3K9 Methylation Features under Hypoxic Conditions after the HIF1A Knockdown in Mesenchymal Stromal Cells In Vitro., PMID:39259464
KDM3A Ablation Activates Endogenous Retrovirus Expression to Stimulate Antitumor Immunity in Gastric Cancer., PMID:39031630
Stem cell-conditioned medium improves methylation patterns and quality of caprine preantral follicles., PMID:38941180
Hif3α Plays Key Roles in the Progression of Alzheimer's Disease Caused by Circadian Rhythm Disruption through Regulating the m6A/KDM3A/TGF-β1 Axis., PMID:38927292
Epigenetic roles of KDM3B and KDM3C in tumorigenesis and their therapeutic implications., PMID:38926399
DcR3-associated risk score: correlating better prognosis and enhanced predictive power in colorectal cancer., PMID:38890197
KDM3A knockdown regulates COMP, LOX, COL8A1 and ACOT1 genes in myocardial fibrosis., PMID:38854759
Reduction of H3K9 methylation by G9a inhibitors improves the development of mouse SCNT embryos., PMID:38729154
LncRNA-PCat19 acts as a ceRNA of miR-378a-3p to facilitate microglia activation and accelerate chronic neuropathic pain in rats by promoting KDM3A-mediated BDNF demethylation., PMID:38643689
Lysine demethylase 3A promotes chondrogenic differentiation of aged human dental pulp stem cells., PMID:38303882
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression., PMID:38286256
Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis., PMID:38165573
LncRNA USP2-AS1 facilitates the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting KDM3A/ETS1/USP2 to activate the Wnt/β-catenin signaling pathway., PMID:38131611
Lysine demethylase 3A in hypoxic macrophages promotes ovarian cancer development through regulation of the vascular endothelial growth factor A/Akt signaling., PMID:37890327
Histone Demethylase KDM3 (JMJD1) in Transcriptional Regulation and Cancer Progression., PMID:37751136
Trimethylation profile of histones H3 lysine 4 and 9 in late preantral and early antral caprine follicles grown in vivo versus in vitro in the presence of anethole., PMID:37671983
Predictive Models for Colon Adenocarcinoma Diagnosis, Prognosis, and Immune Microenvironment Based on 2 Hypoxia-Related Genes: KDM3A and ENO3., PMID:37650153
Sleep Disorder Kleine-Levin Syndrome (KLS) Joins the List of Polygenic Brain Disorders Associated with Obstetric Complications., PMID:37553546
Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability., PMID:37414849
KDM3A and KDM3B Maintain Naïve Pluripotency Through the Regulation of Alternative Splicing., PMID:37398291
Lysine 68 Methylation-Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells., PMID:37386801
Mechanism of NURP1 in temozolomide resistance in hypoxia-treated glioma cells via the KDM3A/TFEB axis., PMID:37305393
Inflammatory stimulation of astrocytes affects the expression of miRNA-22-3p within NSCs-EVs regulating remyelination by targeting KDM3A., PMID:36959678
Promotion of colorectal cancer by transcription factor BHLHE40 involves upregulation of ADAM19 and KLF7., PMID:36890812
The SET oncoprotein promotes estrogen-induced transcription by facilitating establishment of active chromatin., PMID:36791099
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions., PMID:36733232
Role of sevoflurane in myocardial ischemia-reperfusion injury via the ubiquitin-specific protease 22/lysine-specific demethylase 3A axis., PMID:36700466
[Expression pattern of the histone lysine demethylase family and its potential role in bladder cancer: a multi-omics analysis]., PMID:36651250
In silico Identification of Hypoxic Signature followed by reverse transcription-quantitative PCR Validation in Cancer Cell Lines., PMID:36624663
Comprehensive Analyses of Prognostic Values and Immune Infiltration of KDM3 Gene Family in Hepatocellular Carcinoma., PMID:36181608
MiR-22-3p regulates the proliferation, migration and invasion of colorectal cancer cells by directly targeting KDM3A through the Hippo pathway., PMID:36173030
KDM3A promotes oral squamous cell carcinoma cell proliferation and invasion via H3K9me2 demethylation-activated DCLK1., PMID:36094735
KDM3A Attenuates Myocardial Ischemic and Reperfusion Injury by Ameliorating Cardiac Microvascular Endothelial Cell Pyroptosis., PMID:36092165
Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature., PMID:36008383
Taurine inhibits KDM3a production and microglia activation in lipopolysaccharide-treated mice and BV-2 cells., PMID:35901929
Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analysis for KDM3A., PMID:35625569
KDM3A-mediated SP1 activates PFKFB4 transcription to promote aerobic glycolysis in osteosarcoma and augment tumor development., PMID:35590288
Expression of proliferation-related genes in BM-MSC-treated ALL cells in hypoxia condition is regulated under the influence of epigenetic factors in-vitro., PMID:35581482
Histone demethylase JHDM2A participates in the repair of arsenic-induced DNA damage in L-02 cells by regulating DDB2., PMID:35579678
For research use only. Not for human or drug use.
