Catalog No.
YHD28401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg180
Predicted molecular weight
22.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P18085
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADP-ribosylation factor 4, ARF4, ARF2
Normal hearing function genetics: have you heard all about it? An integrated approach of genome-wide association studies and transcriptome-wide association studies in three Italian cohorts., PMID:40458558
Role of IRF4 in mediating plasmablast differentiation in diffuse large B-cell lymphomas via mTORC1 pathway., PMID:40204935
[Quercetin inhibits proliferation and migration of clear cell renal cell carcinoma cells by regulating TP53 gene]., PMID:40031975
ARF4-mediated intracellular transport as a broad-spectrum antiviral target., PMID:39972062
Conserved roles of ETT and ARF4 in gynoecium development in Brassicaceae with distinct fruit shapes., PMID:39936596
The Identification of Auxin Response Factors and Expression Analyses of Different Floral Development Stages in Roses., PMID:39858591
Integrated Analysis of Single-Cell and Bulk RNA Data Reveals Complexity and Significance of the Melanoma Interactome., PMID:39796775
[Characterization of host factors ARF4 and ARF5 upon Zika virus infection in vivo by construction of gene knockout mice]., PMID:39722520
Electroacupuncture pretreatment ameliorates Golgi stress and the inflammation response against endotoxin-induced lung injury., PMID:39709911
H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication., PMID:39652582
Endothelial NMMHC IIA dissociation from PAR1 activates the CREB3/ARF4 signaling in thrombin-mediated intracerebral hemorrhage., PMID:39521432
Reticulophagy and viral infection., PMID:39394962
The MdIAA29-MdARF4 complex plays an important role in balancing plant height with salt and drought stress responses., PMID:39230895
Neutrophil-specific interactome of ARHGAP25 reveals novel partners and regulatory insights., PMID:39210013
Natural variation in root traits identifies significant SNPs and candidate genes for phosphate deficiency tolerance in Zea mays L., PMID:38887929
Cholesterol 25-Hydroxylase Protects Against Diabetic Kidney Disease by Regulating ADP Ribosylation Factor 4., PMID:38816950
Association of ADP‑ribosylation factor family genes with prognosis and immune infiltration of breast cancer., PMID:38699662
Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5., PMID:38679330
A lateral organ boundaries domain transcription factor acts downstream of the auxin response factor 2 to control nodulation and root architecture in Medicago truncatula., PMID:38666352
Pan-cancer analysis of ARFs family and ARF5 promoted the progression of hepatocellular carcinoma., PMID:38617932
ARF4-mediated retrograde trafficking as a driver of chemoresistance in glioblastoma., PMID:38506351
Genome-wide association analysis reveals genes controlling an antagonistic effect of biotic and osmotic stress on Arabidopsis thaliana growth., PMID:38460112
Modulating Golgi Stress Signaling Ameliorates Cell Morphological Phenotypes Induced by CHMP2B with Frontotemporal Dementia-Associated p.Asp148Tyr., PMID:38392208
The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium., PMID:38378792
Toxoplasma and Plasmodium associate with host Arfs during infection., PMID:38349168
Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2., PMID:38072052
ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development., PMID:37848288
The role of vesicle trafficking genes in osteoblast differentiation and function., PMID:37752218
Droj2 Facilitates Somatosensory Neurite Sculpting via GTP-Binding Protein Arf102F in Drosophila., PMID:37686022
FTD/ALS Type 7-Associated Thr104Asn Mutation of CHMP2B Blunts Neuronal Process Elongation, and Is Recovered by Knockdown of Arf4, the Golgi Stress Regulator., PMID:37606396
Oxidized phospholipids facilitate calcific aortic valve disease by elevating ATF4 through the PERK/eIF2α axis., PMID:37462732
The SlARF4-SlHB8 regulatory module mediates leaf rolling in tomato., PMID:37454820
STED imaging of endogenously tagged ARF GTPases reveals their distinct nanoscale localizations., PMID:37102998
Identification and evaluation of novel serum autoantibody biomarkers for early diagnosis of gastric cancer and precancerous lesion., PMID:37079049
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation., PMID:36685499
Ecotype-specific blockage of tasiARF production by two different RNA viruses in Arabidopsis., PMID:36197942
Melon shoot organization 1, encoding an AGRONAUTE7 protein, plays a crucial role in plant development., PMID:35802144
Beta-Cell Golgi Stress Response to Lipotoxicity and Glucolipotoxicity: A Preliminary Study of a Potential Mechanism of Beta-Cell Failure in Posttransplant Diabetes and Intraportal Islet Transplant., PMID:35791832
Auxin-driven ecophysiological diversification of leaves in domesticated tomato., PMID:35639975
Nitric oxide is involved in hydrogen sulfide-induced adventitious rooting in tomato (Solanum lycopersicum)., PMID:34991782
Shared and specific functions of Arfs 1-5 at the Golgi revealed by systematic knockouts., PMID:34749397
Arabidopsis ASYMMETRIC LEAVES2 (AS2): roles in plant morphogenesis, cell division, and pathogenesis., PMID:34668105
USP7 inhibition induces apoptosis in glioblastoma by enhancing ubiquitination of ARF4., PMID:34556124
Lactobacillus rhamnosus GG Promotes Early B Lineage Development and IgA Production in the Lamina Propria in Piglets., PMID:34497150
Arf GTPases Are Required for the Establishment of the Pre-Assembly Compartment in the Early Phase of Cytomegalovirus Infection., PMID:34440611
Knockout of Auxin Response Factor SlARF4 Improves Tomato Resistance to Water Deficit., PMID:33805879
Quantitative Proteomics Reveals Association of Neuron Projection Development Genes ARF4, KIF5B, and RAB8A With Hirschsprung Disease., PMID:33561610
microRNA‑196a‑3p inhibits cell proliferation and promotes cell apoptosis by targeting ADP ribosylation factor 4 in diffuse large B‑cell lymphoma., PMID:33416178
Identification of the Biomarkers and Pathological Process of Heterotopic Ossification: Weighted Gene Co-Expression Network Analysis., PMID:33391181
A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization., PMID:33359467