Catalog No.
YHG08701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg10-Gly95
Predicted molecular weight
23.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06413
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MEF2C, Myocyte-specific enhancer factor 2C, Myocyte enhancer factor 2C
Biological mechanisms of sleep/wake related function., PMID:40506004
Integrated Analysis of DNA Methylome and Transcriptome Reveals Regulatory Mechanism in the Longissimus Dorsi of Duroc Pigs., PMID:40497962
Mapping the Interactions Among Class IIa Histone Deacetylases and Myocyte Enhancer Factor 2s., PMID:40478640
Inhibition of the NLR pathway alleviates MAPK1 mutation-driven proliferation and differentiation deficits and enhanced apoptosis in P19 cells., PMID:40466562
The Ubiquitination and Degradation of SH2B3 Mediated by MEF2A/WWP2 Axis Restores Microglial Homeostasis to Alleviate Cerebral Microvascular Endothelial Cell Injury in Ischemic Stroke., PMID:40407948
Chromatin accessibility and transcriptomic profiles of sheep pituitary function associated with fecundity., PMID:40394458
MiR-4472 serves as a potential biomarker for hypoxic-ischemic encephalopathy and promotes neuronal death as well as hypoxic-ischemic brain damage in neonatal rats by targeting MEF2D., PMID:40393156
CD5-positive B-cell acute lymphoblastic leukemia/lymphoma with MEF2D::BCL9 mimicking aggressive mature B-cell lymphoma: a case report of a newly described entity and potential diagnostic pitfall., PMID:40358810
miR-92a-1-5p targets MEF2A to induce insulin resistance in myocardial ischemia/reperfusion injury., PMID:40345013
Downregulation of SENP1 impairs nuclear condensation of MEF2C and deteriorates ischemic cardiomyopathy., PMID:40341856
[The pleiotropic role of MEF2C in bone tissue development and metabolism]., PMID:40326079
Osthole Induces Hepatic Stellate Cell Ferroptosis to Alleviate Liver Fibrosis by Inhibiting the Y-Box Binding Protein 1-Wnt/β-Catenin Axis Through Downregulating Myocyte Enhancer Factor 2A., PMID:40317895
MEF2A, MEF2C, and MEF2D as potential biomarkers of pancreatic cancer?, PMID:40281485
Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk-stimulated mouse MA-10 Leydig cells., PMID:40277654
An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function., PMID:40270544
HDAC4 suppresses porcine epidemic diarrhea virus infection through negatively regulating MEF2A-GLUT1/3 axis- mediated glucose uptake., PMID:40250106
HD6277 Suppresses Muscle Atrophy by Promoting Myogenic Factors and Inhibiting Proteolysis in Aged Mice., PMID:40229990
Mef2c Controls Postnatal Callosal Axon Targeting by Regulating Sensitivity to Ephrin Repulsion., PMID:40228894
Rewired m6A methylation of promoter antisense RNAs in Alzheimer's disease regulates global gene transcription in the 3D nucleome., PMID:40196645
Balancing LncRNA H19 and miR-675 Bioconversion as a Key Regulator of Embryonic Myogenesis Under Maternal Obesity., PMID:40162559
Massively parallel reporter assays identify functional enhancer variants at QT interval GWAS loci., PMID:40161821
Investigating the Role and Regulatory Mechanisms of the Histone Deacetylase 4 Gene in Chondrocyte Differentiation Impairments Associated With Kashin-Beck Disease., PMID:40143630
The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2., PMID:40139186
High glucose-induced alternative splicing of MEF2D in macrophages promotes vascular chronic inflammation in type 2 diabetes mellitus by mediating M1 macrophage polarization., PMID:40120344
CircFBLN2 regulates duck myoblast proliferation and differentiation through miR-22-5p and MEF2C interaction., PMID:40120247
Discovery of Novel SIK2/3 Inhibitors for the Potential Treatment of MEF2C+ Acute Myeloid Leukemia (AML)., PMID:40111261
Independent signaling pathways provide a fail-safe mechanism to prevent tumorigenesis., PMID:40093137
PSMD14 Transcriptionally Activated by MEF2A Promotes Pancreatic Cancer Development by Upregulating SPON2 Expression., PMID:40066751
MEF2A promoter methylation negatively regulates mRNA transcription and affects myoblast physiological function in cattle., PMID:40024578
Hippocampal MEF2C phosphorylation mediates synaptic plasticity in lead-induced learning and memory impairments., PMID:39947421
The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression., PMID:39923113
Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice., PMID:39920775
Plasma-derived extracellular vesicles prime alveolar macrophages for autophagy and ferroptosis in sepsis-induced acute lung injury., PMID:39901167
De Novo Chromosomes 3q and 5q Chromothripsis Leads to a 5q14.3 Microdeletion Syndrome Presentation: Case Report and Review of the Literature., PMID:39887826
Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease., PMID:39868232
MEF2C mitigates coronary artery lesions in Kawasaki disease by enhancing endothelial barrier function through KLF2 regulation., PMID:39826452
miR-199a-3p mitigates simulated microgravity-induced cardiac remodeling by targeting MEF2C., PMID:39825691
Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers., PMID:39819837
Construction of a prognostic model for gastric cancer based on immune infiltration and microenvironment, and exploration of MEF2C gene function., PMID:39810215
IL-17 triggers PD-L1 gene transcription in NSCLC cells via TRIM31-dependent MEF2C K63-linked polyubiquitination., PMID:39810133
Identifying genetic susceptibility loci associated with human coronary artery disease., PMID:39787106
Exploring genetic mapping and co-expression patterns to illuminate significance of Tbx20 in cardiac biology., PMID:39777589
Stage-specific modulation of Drosophila gene expression with muscle GAL4 promoters., PMID:39772988
Prader-Willi syndrome protein necdin regulates the nucleocytoplasmic distribution and dopaminergic neuron development., PMID:39738217
An autocrine synergistic desmin-SPARC network promotes cardiomyogenesis in cardiac stem cells., PMID:39734020
Comprehensive Predictions of Mef2-Mediated Chromatin Loops, Which May Inhibit Ubx Binding by Blocking Low-Affinity Binding Sites., PMID:39728086
PRR14 mediates mechanotransduction and regulates myofiber identity via MEF2C in skeletal muscle., PMID:39706290
Maternal high-fat diet orchestrates offspring hepatic cholesterol metabolism via MEF2A hypermethylation-mediated CYP7A1 suppression., PMID:39695937
Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer., PMID:39688912
Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration., PMID:39684625
For research use only. Not for human or drug use.
