Catalog No.
YHA04901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp196
Predicted molecular weight
24.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00194
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RAB27B, Ras-related protein Rab-27B, C25KG
Apoptosis linked gene-2 interacting protein X as a target to regulate the yield of small extracellular vesicles derived from tissue specific mesenchymal stem cells for translational applications., PMID:40499874
Emerging roles of Rab27 proteins: from normal to cancer stem cells., PMID:40460483
Lichong Decoction represses colorectal cancer progression via inhibiting the PINK1/Parkin pathway regulated by Rab27B., PMID:40441460
Mechanism of LINC01018/miR-182-5p/Rab27B in the immune escape through PD-L1-mediated CD8+ T cell suppression in glioma., PMID:40399992
DDX10 Exacerbates Exosomal PD-L1-Dependent T Cell Exhaustion via Phase Separation of Rab27b in Oral Squamous Cell Carcinoma., PMID:40352946
Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells., PMID:40323777
Revealing the role of RAB27 in HER receptor family expression and signaling in melanoma cells., PMID:40038749
Gene Expression Signatures of Porcine Bone Marrow-Derived Antigen-Presenting Cells Infected with Classical Swine Fever Virus., PMID:40006915
Rab27b Promotes Lysosomal Function and Alpha-Synuclein Clearance in Neurons., PMID:39965930
Identification of novel biomarkers associated with immune infiltration in major depression disorder and atopic dermatitis., PMID:39953304
Sodium proton exchanger NHE9 pHine-tunes exosome production by impairing Rab7 activity., PMID:39909375
Positive feedback loop between NRASQ61R mutation and RAB27B expression in endothelial cells., PMID:39899936
TGF-β regulates the release of breast cancer cell-derived extracellular vesicles and the sorting of their protein cargo by downregulating RAB27B expression., PMID:39723610
Impact of Rab27 on Melanoma Cell Invasion and sEV Secretion., PMID:39596498
Regulation of autophagy by Rab27B in colorectal cancer., PMID:39542128
Anoikis-related genes linked with patient outcome in pancreatic cancer., PMID:39154969
Rab27b promotes lysosomal function and alpha-synuclein clearance in neurons., PMID:38979346
Nominating novel proteins for anxiety via integrating human brain proteomes and genome-wide association study., PMID:38697224
Uropathogenic Escherichia coli infection: innate immune disorder, bladder damage, and Tailin Fang II., PMID:38638825
Exosomes biogenesis was increased in metformin-treated human ovary cancer cells; possibly to mediate resistance., PMID:38627767
Tectoridin inhibits the growth of bladder cancer by regulating PI3K/MAPK pathway through RAB27B., PMID:38441297
The genetic regulation of the gastric transcriptome is associated with metabolic and obesity-related traits and diseases., PMID:38406838
Schwann cell-derived exosomes promote lung cancer progression via miRNA-21-5p., PMID:38192185
Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27., PMID:38132356
RAB27B-regulated exosomes mediate LSC maintenance via resistance to senescence and crosstalk with the microenvironment., PMID:38036630
RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C., PMID:37953466
Identification and validation of tumor microenvironment-related signature for predicting prognosis and immunotherapy response in patients with lung adenocarcinoma., PMID:37604869
Renal cancer secretome induces migration of mesenchymal stromal cells., PMID:37563650
An HGF-dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis., PMID:37483113
Melanoma cells with acquired resistance to vemurafenib have decreased autophagic flux and display enhanced ability to transfer resistance., PMID:37419396
Low-dose aspirin can inhibit exosomal release induced by radiotherapy in breast cancer and attenuate its inhibitory effect on NK cell proliferation., PMID:37392173
Mechanisms for regulation of RAS palmitoylation and plasma membrane trafficking in hematopoietic malignancies., PMID:37317974
RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia., PMID:37317963
RAB27B expression in pancreatic cancer is predictive of poor survival but good response to chemotherapy., PMID:37248891
[Silencing RAB27a inhibits proliferation, invasion and adhesion of triple-negative breast cancer cells]., PMID:37202191
α-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification., PMID:37167325
Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure., PMID:37139869
Therapeutic role of FNDC5/irisin in attenuating liver fibrosis via inhibiting release of hepatic stellate cell-derived exosomes., PMID:37046114
Genome-wide identification of A-to-I RNA editing events provides the functional implications in PDAC., PMID:36895481
Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer., PMID:36581340
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy., PMID:36572649
Gelsolin Modulates Platelet Dense Granule Secretion and Hemostasis via the Actin Cytoskeleton., PMID:36522181
Quantitative proteomics identified circulating biomarkers in lung adenocarcinoma diagnosis., PMID:36404333
Type 2 diabetes mellitus stimulated pulmonary vascular inflammation and exosome biogenesis in rats., PMID:36335538
Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy., PMID:36219207
How "Neuronal" Are Human Skin Mast Cells?, PMID:36142795
Identification of Potential miRNA-mRNA Regulatory Network Contributing to Parkinson's Disease., PMID:36105301
Genome-wide detection of copy number variation in American mink using whole-genome sequencing., PMID:36096727
Extracellular vesicles secreted by human uterine stromal cells regulate decidualization, angiogenesis, and trophoblast differentiation., PMID:36095212
Long non-coding RNA LINC01018 inhibits human glioma cell proliferation and metastasis by directly targeting miRNA-182-5p., PMID:36094613
For research use only. Not for human or drug use.
