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Anti-CD66e/CEA/CEACAM5 Polyclonal Antibody

Catalog #:   PHC21001 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P06731
Overview

Catalog No.

PHC21001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD66e/CEA/CEACAM5 (Ala34-Leu234).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Meconium antigen 100,CEACAM5,CEA,CD66e,Carcinoembryonic antigen-related cell adhesion molecule 5,Carcinoembryonic antigen

Purification

Purified by antigen affinity column.

Accession

P06731

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Various lysates were subjected to SDS PAGE followed by western blot with CEACAM5 antibody (PHC21001) at 1µg/ml.

    Lane 1: HT-29 cell lysate
    Lane 2: MCF-7 cell lysate
    Lane 3: BxPC-3 cell lysate
    Lane 4: SW620 cell lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 77 kDa
    Observed MW: 200 kDa
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CD66e/CEA/CEACAM5 antibody (PHC21001) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
References

Application of serum anti-ENO1 and anti-SSNA1 antibody biomarkers in predicting the prognosis of gastric cancer., PMID:40469915

Construction of a simple PEC immunosensing platform based on polydopamine and PEDOT sensitized Bi2WO6 for sensitive detection of carcinoembryonic antigen., PMID:40466205

A Phase I Study of the Anti-CEACAM6 Antibody Tinurilimab (BAY 1834942) in Patients with Advanced Solid Tumors., PMID:40465170

Nanobody-Directed CEA-targeting CAR T Cells Eliminate Gastrointestinal Cancer Xenografts., PMID:40439687

CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma., PMID:40436855

An innovative electrophoresis-coupled electrochemiluminescence immunosensor for rapid and sensitive detection of carcinoembryonic antigen., PMID:40418863

Trace protein detection by graphene-integrated terahertz meta-sensor and enhanced sensitivity using gold nanoparticles-assisted., PMID:40413992

Phase 1 study evaluating safety and pharmacokinetics of tusamitamab ravtansine monotherapy in Japanese patients with advanced malignant solid tumors., PMID:40413667

Modulation of Aggregation of Covalent Organic Framework Nanosheets with Aggregation-Induced Emission Activity for Ultrasensitive No-Wash Fluorescent Immunosensor., PMID:40377048

Artificial intelligence prediction of carcinoembryonic antigen structure and interactions relevant for colorectal cancer., PMID:40330074

Bifunctional S-doping-mediated interfacial gradient electric field for in-situ amplified photoelectrochemical immunoassay., PMID:40319725

Self-assembled nano-hybrid composite based on Cu/CuXO nanoflower decorated onto hBNNS for high-performance and ultra-sensitive electrochemical detection of CEA biomarker., PMID:40315690

Plasma IgG and IgM autoantibodies to COPT1 as potential biomarkers for detection of non-small cell lung cancer., PMID:40292291

Dual-channel, real-time, long-term stable electrochemical immunosensor based on Au, Cu-vertical graphene for detection of carcinoembryonic antigen in tumor cells., PMID:40274336

Multimodal carcinoembryonic antigen-targeted fluorescence and radio-guided cytoreductive surgery for peritoneal metastases of colorectal origin: single-arm confirmatory trial., PMID:40270484

FOLFIRI with cetuximab or bevacizumab in RAS wild-type metastatic colorectal cancer: Refining first-line treatment selection by combining clinical parameters: A post hoc analysis of the randomized open-label phase III trial FIRE-3/AIO KRK0306., PMID:40179821

A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors., PMID:40158720

New World Primates and Their Human Counterparts Share Diseases That Abound with CEACAM and Other Effector Molecules., PMID:40141825

Cerebrospinal fluid cytology for the diagnosis of lung cancer brain metastasis: a case report., PMID:40114958

Development of Anti-CEA CH2 Domain-Deleted Antibody (M5A∆CH2) for the PET Imaging of Colorectal Cancer., PMID:40085171

Harnessing bifunctional nanozyme with potent catalytic and signal amplification for innovating electrochemical immunoassay., PMID:40064571

Gold Nanoparticle Incorporated Graphene Oxide as a SERS Platform for Ultratrace Antibody Free Sensing of the Cancer Biomarker CEA., PMID:40062598

Highly sensitive detection of carcinoembryonic antigen via an electrochemical platform fabricated by CCLP- gold nanocomposite., PMID:40049234

Integrated Device for Cancer Nucleic Acid Biomarker Detection at Body Temperature., PMID:40047709

Ultrasensitive CEA detection using SiO2/AuNPs-mediated dual inhibition in a signal-off-type photoelectrochemical immunosensor., PMID:40015784

A Dual Nano-Signal Probe-Based Electrochemical Immunosensor for the Simultaneous Detection of Two Biomarkers in Gastric Cancer., PMID:39996982

Bidirectionally Favorable Platform: A Dual-Targeting Probe-Encoded Maple Leaf-Type Fluorescent Lateral Flow Immunoassay for Multiple Biomarker Detection., PMID:39962727

Multifunctional dopamine-modified conjugated polymer nanoparticles for ultrasensitive immunoassays., PMID:39955906

Bi2WO6-labeled antibody induced photocurrent polarity switching of ZnIn2S4-based photoelectrochemical immunosensor for the highly sensitive detection of carcinoembryonic antigen., PMID:39951987

Alkaline Phosphatase: A Prognostic Biomarker in Non-Metastatic Colon Adenocarcinoma Patients - A Single-Centre Study., PMID:39936196

Bright and Specific Targeting of Metastatic Lymph Nodes in Orthotopic Mouse Models of Gastric Cancer with a Fluorescent Anti-CEA Antibody., PMID:39878844

Reanalysis of Urothelial Cancer Chemoimmunotherapy Trials With Differential Censoring., PMID:39841472

Broad-Spectrum Efficacy of CEACAM6-Targeted Antibody-Drug Conjugate with BET Protein Degrader in Colorectal, Lung, and Breast Cancer Mouse Models., PMID:39812376

Antibody-Drug Conjugates in Non-Small Cell Lung Cancer: State of the Art and Future Perspectives., PMID:39796075

Affinity Peptide-Based Circularly Permuted Fluorescent Protein Biosensors for Non-Small Cell Lung Cancer Diagnosis., PMID:39771637

Electrochemical biosensor based on composite of gold nanoparticle/reduced-graphene oxide/graphitic carbon nitride and a caprolactone polymer for highly sensitive detection of CEA., PMID:39764934

Targeting CEA in metastatic triple negative breast cancer with image-guided radiation followed by Fab-mediated chimeric antigen receptor (CAR) T-cell therapy., PMID:39759518

The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients-The Putative Mechanism Behind ILD., PMID:39754485

Characteristics of Nodular Goitre and Its Correlation With Papillary Thyroid Carcinoma: A Cross-Sectional Study., PMID:39737304

Impedimetric Biosensors for the Quantification of Serum Biomarkers for Early Detection of Lung Cancer., PMID:39727890

Point-of-Care Detection of Carcinoembryonic Antigen (CEA) Using a Smartphone-Based, Label-Free Electrochemical Immunosensor with Multilayer CuONPs/CNTs/GO on a Disposable Screen-Printed Electrode., PMID:39727865

Expression-Dependent Tumor Pretargeting via Engineered Avidity., PMID:39704255

Carcinoembryonic Antigen Expression in Human Tumors: A Tissue Microarray Study on 13,725 Tumors., PMID:39682238

Antibody-modified 2D MXene nanosheet probes for selective, picolevel detection of cancer biomarkers., PMID:39647410

Enrichment of carcinoembryonic antigen by epitope molecularly imprinted polymer based on cucurbituril host-guest interaction., PMID:39644742

A bio-nano-engineered platform fabricated from cerium oxide-carbon nanoparticles stabilized with chitosan for label-free sensing of a lung cancer biomarker., PMID:39633582

Neisseria gonorrhoeae induces local secretion of IL-10 at the human cervix to promote colonization., PMID:39585777

Lenvatinib, sintilimab combined interventional treatment vs bevacizumab, sintilimab combined interventional treatment for intermediate-advanced unresectable hepatocellular carcinoma., PMID:39575400

Case report: A golden tail of immunotherapy: significant tail effect in a chemotherapy-resistant advanced pulmonary sarcomatoid carcinoma patient treated by Sintilimab combined with Anlotinib., PMID:39569200

Biomarkers of rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis., PMID:39534599

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CD66e/CEA/CEACAM5 Polyclonal Antibody [PHC21001]
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