Catalog No.
YHB85701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp88-Leu227
Predicted molecular weight
18.12 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00403
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COXII, COII, COX2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, MT-CO2, MTCO2
Note
For research use only.
Mitochondrial Gene Expression Profiles Are Associated with Maternal Psychosocial Stress in Pregnancy and Infant Temperament., PMID:26418562
Increased Expression of Beige/Brown Adipose Markers from Host and Breast Cancer Cells Influence Xenograft Formation in Mice., PMID:26464213
Whole mitochondrial genome screening of a family with maternally inherited diabetes and deafness (MIDD) associated with retinopathy: A putative haplotype associated to MIDD and a novel MT-CO2 m.8241T>G mutation., PMID:27422531
Lethal Neonatal LTBL Associated with Biallelic EARS2 Variants: Case Report and Review of the Reported Neuroradiological Features., PMID:27571996
Case report: a novel frameshift mutation in the mitochondrial cytochrome c oxidase II gene causing mitochondrial disorder., PMID:28521807
Variants m.13276G>A in the MT-ND5 and m.8241T>G in the MT-CO2 gene are not responsible for maternally inherited diabetes and deafness., PMID:28890306
Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)., PMID:28978032
Potential to curb the environmental burdens of American beef consumption using a novel plant-based beef substitute., PMID:29211775
Integrative Analysis to Identify Common Genetic Markers of Metabolic Syndrome, Dementia, and Diabetes., PMID:29229897
Integrated 'omics analysis reveals new drug-induced mitochondrial perturbations in human hepatocytes., PMID:29501571
Myocardial insufficiency is related to reduced subunit 4 content of cytochrome c oxidase., PMID:30223867
Mitochondrial complex IV deficiency caused by a novel frameshift variant in MT-CO2 associated with myopathy and perturbed acylcarnitine profile., PMID:30315213
α-Synuclein induced mitochondrial dysfunction via cytochrome c oxidase subunit 2 in SH-SY5Y cells., PMID:30776354
Whole mitochondria genome mutational spectrum in occupationally exposed lead subjects., PMID:31029642
PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis., PMID:31177901
DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B., PMID:31251111
ESCRT-mediated phagophore sealing during mitophagy., PMID:31366282
Mitochondrial protein enriched extracellular vesicles discovered in human melanoma tissues can be detected in patient plasma., PMID:31497264
Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort., PMID:31577800
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain., PMID:31628462
Platelet mitochondrial DNA methylation predicts future cardiovascular outcome in adults with overweight and obesity., PMID:32066501
Novel Point Mutations in Mitochondrial MT-CO2 Gene May Be Risk Factors for Coronary Artery Disease., PMID:32096057
Varicella-Zoster Virus infected human neurons are resistant to apoptosis., PMID:32125664
PPRC1, but not PGC-1α, levels directly correlate with expression of mitochondrial proteins in human dermal fibroblasts., PMID:32639509
The genomic analysis of endometrial mitochondrial DNA copy number variation on recurrent implantation failure., PMID:33075545
Mechanism of Naringenin Blocking the Protection of LTB4/BLT1 Receptor Against Septic Cardiac Dysfunction., PMID:33334792
Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy., PMID:33499712
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1., PMID:33691743
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes., PMID:34145303
Autophagy deficiency abolishes liver mitochondrial DNA segregation., PMID:35220898
Synthetic antibody-derived immunopeptide provides neuroprotection in glaucoma through molecular interaction with retinal protein histone H3.1., PMID:36313990
Use of dual genomic sequencing to screen mitochondrial diseases in pediatrics: a retrospective analysis., PMID:36918699
Copper metabolism in cell death and autophagy., PMID:37055935
Screening of the differentially expressed proteins in malignant transformation of BEAS-2B cells induced by coal tar pitch extract., PMID:37125331
Mutations in Structural Genes of the Mitochondrial Complex IV May Influence Breast Cancer., PMID:37510369
Molecular mechanisms regulating natural menopause in the female ovary: a study based on transcriptomic data., PMID:37564980
Pain/Stress, Mitochondrial Dysfunction, and Neurodevelopment in Preterm Infants., PMID:38286121
Cuproptosis-associated hub gene identification and immune cell infiltration patterns in silicosis., PMID:38403151
Effects of Tcte1 knockout on energy chain transportation and spermatogenesis: implications for male infertility., PMID:38650655
Chronic Exposure to Arsenic and Fluoride Starting at Gestation Alters Liver Mitochondrial Protein Expression and Induces Early Onset of Liver Fibrosis in Male Mouse Offspring., PMID:38676876
Cannabinerol Prevents Endoplasmic Reticulum and Mitochondria Dysfunctions in an In Vitro Model of Alzheimer's Disease: A Network-Based Transcriptomic Analysis., PMID:38920643
Preserving mitochondrial homeostasis protects against drug-induced liver injury via inducing OPTN (optineurin)-dependent Mitophagy., PMID:39099169
Bunyavirus SFTSV nucleoprotein exploits TUFM-mediated mitophagy to impair antiviral innate immunity., PMID:39189526
MST1, a novel therapeutic target for Alzheimer's disease, regulates mitochondrial homeostasis by mediating mitochondrial DNA transcription and the PI3K-Akt-ROS pathway., PMID:39578795
Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation., PMID:39747079
Predicting the hub interactome of COVID-19 and oral squamous cell carcinoma: uncovering ALDH-mediated Wnt/β-catenin pathway activation via salivary inflammatory proteins., PMID:39901050
Effects of marijuana and tobacco on male fertility and their relationship to genetic variation of mitochondrial cytochrome C oxidase genes., PMID:40038427
Inhibition of PINK1 senses ROS signaling to facilitate neuroblastoma cell pyroptosis., PMID:40160153
A new set of mutations in the second transmembrane helix of the Cox2p-W56R substantially improves its allotopic expression in Saccharomyces cerevisiae., PMID:40178993
Cadmium Exposure Disrupts Uterine Energy Metabolism and Coagulation Homeostasis During Labor in Institute of Cancer Research Mice: Insights from Transcriptomic Analysis., PMID:40422915
For research use only. Not for human or drug use.
