Research Grade Anti-Human CDH6/Cadherin-6 (HKT288)

Catalog No.

DHF11804

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1

Clonality

Monoclonal

Target

K-cadherin, CDH6, Cadherin-6, Kidney cadherin

Concentration

1.8 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P55285

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

LTV977

Clone ID

HKT288

A Phase 1 Study of a CDH6-Targeting Antibody-Drug Conjugate in Patients with Advanced Solid Tumors with Evaluation of Inflammatory and Neurological Adverse Events., PMID:34515215

Utilizing panels of patient derived xenografts to aid the development of antibody drug conjugates., PMID:29404392

Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers., PMID:28526733

Document Download

Research Grade Anti-Human CDH6/Cadherin-6 (HKT288).pdf