Catalog No.
DHE70201
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
PLGF, PGF, PlGF, PGFL, Placenta growth factor
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P49763
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
TB-403, TB 403, TB403
Clone ID
TB-403
A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma., PMID:35833850
An apparent clinical pharmacokinetic drug-drug interaction between bevacizumab and the anti-placental growth factor monoclonal antibody RO5323441 via a target-trapping mechanism., PMID:28314990
Phase 1 dose-escalation study of the antiplacental growth factor monoclonal antibody RO5323441 combined with bevacizumab in patients with recurrent glioblastoma., PMID:25665807
Inhibition of placental growth factor in renal cell carcinoma., PMID:25550599
Glioma cell-derived placental growth factor induces regulatory B cells., PMID:25450457
Placental growth factor (PlGF)-specific uptake in tumor microenvironment of 89Zr-labeled PlGF antibody RO5323441., PMID:23625582
Inhibition of placenta growth factor with TB-403: a novel antiangiogenic cancer therapy., PMID:22506966
A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumours., PMID:22333707
Monoclonal antibody TB-403: a first-in-human, Phase I, double-blind, dose escalation study directed against placental growth factor in healthy male subjects., PMID:21906811
Is quarterly cohort analysis useful for assessing treatment outcomes in a low incidence country?, PMID:11326824
For research use only. Not for human or drug use.
