Catalog No.
DHD34002
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
TNFR-I, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, TBPI, p60, CD120a, TNFRSF1A, Tumor necrosis factor receptor type I, p55, TNF-RI, TNFAR, TNFR1, TNF-R1
Concentration
2.48 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P19438
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
ATROSAB
Clone ID
ATROSAB
Tumor Necrosis Factor Alpha Blockade and Multiple Sclerosis: Exploring New Avenues., PMID:34804701
TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice., PMID:32235829
Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity., PMID:30252601
Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis., PMID:30206422
Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration., PMID:27791020
An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action., PMID:24006371
Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity., PMID:23977237
Process development of ATROSAB, an anti TNFR1 Monoclonal Antibody: in three steps from research to GMP., PMID:22373224
ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one-specific antibody., PMID:20935477
For research use only. Not for human or drug use.
