Catalog No.
DHF95601
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
VMCM, TIE2, Tunica interna endothelial cell kinase, CD202b, Tyrosine-protein kinase receptor TIE-2, TEK, Angiopoietin-1 receptor, VMCM1, Endothelial tyrosine kinase, Tyrosine-protein kinase receptor TEK, p140 TEK, Tyrosine kinase with Ig and EGF homology domains-2, hTIE2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q02763
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
UBX2050
Clone ID
UBX2050
The VALTIVE1 study protocol: a study for the validation of Tie2 as the first tumour vascular response biomarker for VEGF inhibitors., PMID:39448911
Targeting the Tie-2 Receptor With Faricimab in Central Serous Chorioretinopathy: A Case Series Motivated by a Genetic Finding., PMID:39233019
Expression of Tie2 (angiopoietin receptor) on the monocyte subpopulations from ischemic stroke patients: Histological and flowcytometric studies., PMID:36876965
Designed proteins assemble antibodies into modular nanocages., PMID:33795432
Faricimab: an investigational agent targeting the Tie-2/angiopoietin pathway and VEGF-A for the treatment of retinal diseases., PMID:33471572
Spheroid-Like Cultures for Expanding Angiopoietin Receptor-1 (aka. Tie2) Positive Cells from the Human Intervertebral Disc., PMID:33322051
A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure., PMID:33315051
Targeting Angiopoietin in Retinal Vascular Diseases: A Literature Review and Summary of Clinical Trials Involving Faricimab., PMID:32785136
Tie-2/Angiopoietin pathway modulation as a therapeutic strategy for retinal disease., PMID:31513439
Phase II trial of ponatinib in patients with bevacizumab-refractory glioblastoma., PMID:31444999
Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2., PMID:31427368
Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients., PMID:31377797
Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer., PMID:30405103
CD133 positive progenitor endothelial cell lines from human cord blood., PMID:21710642
For research use only. Not for human or drug use.
