Catalog No.
DHC36908
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
sIL6R, Interleukin-6 receptor subunit alpha, CD126, IL-6R 1, IL-6R subunit alpha, Membrane glycoprotein 80, gp80, IL6R, IL-6RA, IL-6 receptor subunit alpha, IL-6R-alpha
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P08887
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
MSB11456
Clone ID
MSB11456
Hemoadsorption as a Supportive Strategy for Severe Toxicity Associated With Chimeric Antigen Receptor T-Cell Therapy: A Case Series., PMID:40510619
Key indicators for guiding tocilizumab therapy to prevent orbital decompression surgery in hormone-resistant dysthyroid optic neuropathy., PMID:40510358
The clinical toxicity of advanced therapy medicinal products., PMID:40509780
Sarilumab in the treatment of rheumatoid arthritis: future perspectives., PMID:40506803
Pulmonary Aspergillosis: Epidemiology and unresolved diagnostic challenges - insights from a two-year retrospective cohort study in Marseille., PMID:40505837
Unravelling VEXAS syndrome: shedding light on a recently recognised medical condition., PMID:40499953
A rare case report: acute necrotizing encephalopathy and acute fulminant myocarditis., PMID:40495992
Clinical characteristics and treatment of infantile Takayasu arteritis in the Chinese Han population: a single-center study., PMID:40495185
Therapeutic Choices in Systemic Sclerosis-Associated Interstitial Lung Disease, a Survey of 2 International Research Groups., PMID:40489954
Management of Patients With COVID-19 During the Pandemic: A Retrospective Cohort Study From a Tertiary Care Centre in Mumbai, India., PMID:40486438
Minocycline in chronic management of febrile infection-related epilepsy syndrome (FIRES): a case series and literature review of treatment strategies., PMID:40481521
Glucocorticoid treatment in early rheumatoid arthritis is independently associated with increased PCSK9 levels: data from a randomised controlled trial., PMID:40480650
Tumefactive demyelination as the first presentation of MOG ab-associated disease., PMID:40479755
Efficacy of tocilizumab monotherapy after ultrashort glucocorticoid administration to treat giant cell arteritis: three year follow-up., PMID:40478774
[VEXAS Syndrome]., PMID:40476413
Steroid refractory immune-related acute disseminated encephalomyelitis (ADEM) successfully treated with 2nd and 3rd line immunosuppressive therapy., PMID:40473324
[Clinical phenotype and genotype analysis of neuroinflammation, autoinflammation, splenomegaly and anemia syndrome caused by IRAK4 gene variant]., PMID:40468499
Belatacept in Kidney Transplantation: Reflecting on the Past, Shaping the Future., PMID:40463417
[Sequential treatment with siltuximab and tocilizumab for childhood idiopathic multicentric Castleman disease: a case report]., PMID:40462437
Baricitinib and Tocilizumab in COVID-19: A Call for Deeper Mechanistic and Methodological Exploration., PMID:40459395
IL-6R blockade combined with immunosuppressants alleviates adult-onset Still's disease through immune remodeling: a mass cytometry study., PMID:40457438
Tocilizumab-Based Treatment of Microvascular Inflammation in Kidney Transplant Recipients: A Retrospective Study., PMID:40454296
The first nationwide epidemiological survey of chronic recurrent multifocal osteomyelitis in Japan., PMID:40445191
Physician Burden and Time Delays in Initiating Immunomodulatory Therapy for Non-infectious Uveitis and Inflammatory Eye Diseases., PMID:40441503
Antibody-mediated Rejection - Treatment Standard., PMID:40440205
Mendelian randomisation and infection: pitfalls and promises., PMID:40435229
Successful treatment with tocilizumab in a case of familial Mediterranean fever with Takayasu arteritis., PMID:40433865
Use of Immune Modulating Agents to Regulate Hyperinflammation in Severe COVID 19: Assessment of Tocilizumab Use in Combination with Steroids., PMID:40432839
Efficacy of Tofacitinib in Takayasu Arteritis Refractory to Biologic DMARDs-A Multicentre Study in Indian Patients., PMID:40432338
New Challenging Systemic Therapies for Juvenile Scleroderma: A Comprehensive Review., PMID:40430462
Experience of High Tibial Osteotomy for Patients with Rheumatoid Arthritis Treated with Recent Medication: A Case Series., PMID:40429328
Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia., PMID:40424990
Tocilizumab prophylaxis in double cord blood transplantation., PMID:40423984
Phase 2 trial of cyclosporine-A, mycophenolate mofetil, and tocilizumab GVHD prophylaxis in cord blood transplantation., PMID:40423982
Polyangiitis overlap syndrome is a high-risk clinical phenotype for relapse: case series from the KEIO-vasculitis cohort., PMID:40421732
Anti-MDA5 antibody positive dermatomyositis complicated by interstitial lung disease with an improved outcome: A case report., PMID:40419927
Tocilizumab effectiveness in paediatric non-infectious uveitis: data from the International AIDA Network Registries on ocular inflammatory disorders., PMID:40413020
Treatment outcomes in patients with VEXAS syndrome: a retrospective cohort study., PMID:40412417
Integrative genome-wide association studies, proteome-wide Mendelian randomization, and single-cell RNA sequencing identify interleukin-6 receptor protein as a therapeutic target in aortic aneurysm., PMID:40409638
Management of immune-related myocarditis, myositis and myasthenia gravis (MMM) overlap syndrome: a single institution case series and literature review., PMID:40406130
Comparative efficacy and safety of rituximab, tocilizumab, and teprotumumab in Graves' orbitopathy: a systematic review and meta-analysis., PMID:40404973
[Update of clinical management in autoimmune encephalitis-2004]., PMID:40399061
Pediatric-Onset Neuromyelitis Optica Spectrum Disorder: Long-term Follow-up and Therapeutic Challenges in a Treatment-Resistant Case., PMID:40398846
Comparative effectiveness of intravenous versus subcutaneous tocilizumab for refractory uveitis: a retrospective analysis., PMID:40398691
Thyroid eye disease in the biologic era: a 40-year paradigm shift in nonsurgical therapeutic strategies., PMID:40397653
[Clinical phenotype and genotype analysis of neuroinflammation, autoinflammation, splenomegaly and anemia syndrome caused by IRAK4 gene variantion]., PMID:40393760
Combined IVIG and High-Dose Systemic Corticosteroids for the Management of Pembrolizumab-Induced Cytokine Release Syndrome in Lung Adenocarcinoma., PMID:40391237
Tocilizumab Monotherapy or Combined With Methotrexate for Rheumatoid Arthritis: A Randomized Clinical Trial., PMID:40388166
Evolving therapeutic strategies for severe fever with thrombocytopenia syndrome: from past to future., PMID:40385974
Bilateral Alternate Orbital and Ocular Manifestations in a VEXAS Syndrome Patient., PMID:40384388
For research use only. Not for human or drug use.
