Catalog No.
PHC06301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PDGFA (Ser87-Thr211).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Platelet-derived growth factor alpha polypeptide,Platelet-derived growth factor subunit A,Platelet-derived growth factor A chain,PDGF subunit A,PDGFA,PDGF-1,PDGF1
Purification
Purified by antigen affinity column.
Accession
P04085
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
[Efficient capture and proteomics analysis of urinary extracellular vesicles by affinity purification]., PMID:40331614
Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia., PMID:38804310
Effects of acetazolamide combined with remote ischemic preconditioning on risk of acute mountain sickness: a randomized clinical trial., PMID:38166913
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis., PMID:37756381
HMGB1, a potential regulator of tumor microenvironment in KSHV-infected endothelial cells., PMID:37520371
An angiogenic tumor phenotype predicts poor prognosis in ovarian cancer., PMID:36758419
Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages., PMID:35997026
Combination of sunitinib and 177Lu-labeled antibody cG250 targeted radioimmunotherapy: A promising new therapeutic strategy for patients with advanced renal cell cancer., PMID:35878454
PDGFA-associated protein 1 is a novel target of c-Myc and contributes to colorectal cancer initiation and progression., PMID:35716012
Immunotherapy and Radioimmunotherapy for Desmoplastic Small Round Cell Tumor., PMID:34869013
Regulation of Transplanted Cell Homing by FGF1 and PDGFB after Doxorubicin Myocardial Injury., PMID:34831221
Telocytes in the human ascending aorta: Characterization and exosome-related KLF-4/VEGF-A expression., PMID:34562312
Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas., PMID:33524869
Pretreatment of aged mice with retinoic acid supports alveolar regeneration via upregulation of reciprocal PDGFA signalling., PMID:33479039
A Novel Pharmacodynamic Biomarker and Mechanistic Modeling Facilitate the Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer Therapy., PMID:33210183
Non-invasive Embryo Assessment: Altered Individual Protein Profile in Spent Culture Media from Embryos Transferred at Day 5., PMID:33151525
The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells., PMID:33045196
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification., PMID:32609329
A novel proangiogenic B cell subset is increased in cancer and chronic inflammation., PMID:32426497
The role of bone-derived PDGF-AA in age-related pancreatic β cell proliferation and function., PMID:31980171
New therapeutic targets in the treatment of age-related macular degeneration., PMID:31787390
Metastatic Breast Carcinoma-Associated Fibroblasts Have Enhanced Protumorigenic Properties Related to Increased IGF2 Expression., PMID:31515454
Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways., PMID:31303763
PDGF regulated migration of mesenchymal stem cells towards malignancy acts via the PI3K signaling pathway., PMID:30347613
Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes., PMID:29728363
Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer., PMID:29342159
PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT., PMID:29282077
Retinal Astrocytes and GABAergic Wide-Field Amacrine Cells Express PDGFRα: Connection to Retinal Ganglion Cell Neuroprotection by PDGF-AA., PMID:28910446
Protein microarray analysis identifies key cytokines associated with malignant middle cerebral artery infarction., PMID:28828208
Dynamics of Inflammatory Factors in Aqueous Humor during Ranibizumab or Aflibercept Treatment for Age-Related Macular Degeneration., PMID:28796997
The tyrosine kinase inhibitors effects on metastatic tumor graft in the chick chorioallantoic membrane assay., PMID:29556614
Identification of cytokines for early prediction of malignant middle cerebral artery infarction., PMID:26981614
Exogenous S100A8 protein inhibits PDGF-induced migration of airway smooth muscle cells in a RAGE-dependent manner., PMID:26920052
[Relationship between the levels and variation of CXCL12, PDGF, CXCL14 in cerebrospinal fluid of optic neuritis and neuromyelitis optica]., PMID:26888271
Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function., PMID:26769046
Sphere formation of adipose stem cell engineered by poly-2-hydroxyethyl methacrylate induces in vitro angiogenesis through fibroblast growth factor 2., PMID:26498525
Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array., PMID:26258407
Alterations in platelet-derived growth factor expression in the pathophysiology of necrotizing enterocolitis., PMID:25899145
Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial., PMID:25867261
Association between gene and miRNA expression profiles and stereotyped subset #4 B-cell receptor in chronic lymphocytic leukemia., PMID:25860243
Naturally occurring PDGF receptor inhibitors with potential anti-atherosclerotic properties., PMID:25737405
Dependence of fibroblast infiltration in tumor stroma on type IV collagen-initiated integrin signal through induction of platelet-derived growth factor., PMID:25686533
Vasopressin regulation of epithelial colonic proliferation and permeability is mediated by pericryptal platelet-derived growth factor A., PMID:25085844
Downregulation of angiogenesis factors, VEGF and PDGF, after rapid IgE desensitization and oral immunotherapy in children with food allergy., PMID:24995287
Effects of activated fibroblasts on phenotype modulation, EGFR signalling and cell cycle regulation in OSCC cells., PMID:24394543
Identification and elimination of target-related matrix interference in a neutralizing anti-drug antibody assay., PMID:24287421
Src tyrosine kinase mediates platelet-derived growth factor BB-induced and redox-dependent migration in metanephric mesenchymal cells., PMID:24197068
Effect of implantation of Augment(®) Bone Graft on serum concentrations of platelet-derived growth factors: a pharmacokinetic study., PMID:23334906
Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts., PMID:22933705
Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF-Akt pathway., PMID:22681587
For research use only. Not for human or drug use.
