Catalog No.
DHD06901
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
IL-2R subunit beta, Interleukin-15 receptor subunit beta, IL2RB, IL-2 receptor subunit beta, CD122, High affinity IL-2 receptor subunit beta, p75, Interleukin-2 receptor subunit beta, IL-2RB, p70-75, IL15RB
Concentration
1.38 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P14784
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
Mik-beta-1, Mik beta 1, Mik-beta1
Clone ID
Mik beta 1
Association Between β-Amyloid Accumulation and Incident Dementia in Individuals 80 Years or Older Without Dementia., PMID:38165336
Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome., PMID:37855447
Predicting resistance to amyloid-beta deposition and cognitive resilience in the oldest-old., PMID:32699143
Laminarans and 1,3-β-D-glucanases., PMID:32663561
Catheter ablation of electrical storm in patients with arrhythmogenic right ventricular cardiomyopathy., PMID:31284048
Novel Enzyme Actions for Sulphated Galactofucan Depolymerisation and a New Engineering Strategy for Molecular Stabilisation of Fucoidan Degrading Enzymes., PMID:30388774
Amyloid deposition and brain structure as long-term predictors of MCI, dementia, and mortality., PMID:29695596
Whole transcriptome analysis of transgenic barley with altered cytokinin homeostasis and increased tolerance to drought stress., PMID:26877151
The biology of IL-15: implications for cancer therapy and the treatment of autoimmune disorders., PMID:24326545
[Effect of efflux pump inhibitor 1-(1-naphthylmethyl)-piperazine to MIC values of ciprofloxacin in ciprofloxacin resistant gram-negative bacteria]., PMID:19795621
[Prevalence of dangerous arrhythmia during pharmacological stress echocardiography]., PMID:17007256
Beta-1,3-glucanase from unfertilized eggs of the sea urchin Strongylocentrotus intermedius. Comparison with beta-1,3-glucanases of marine and terrestrial mollusks., PMID:12882634
Bispecific humanized anti-IL-2 receptor alpha beta antibodies inhibitory for both IL-2- and IL-15-mediated proliferation., PMID:9233654
Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants., PMID:9227332
Activation of naive and memory T cells by interleukin-15., PMID:8704178
IL-15 induces the release of soluble IL-2Ralpha from human peripheral blood mononuclear cells., PMID:8612353
Differential inhibition of lymphokine-activated killing, proliferation, and cytokine secretion by humanized antibodies against the low- and intermediate-affinity interleukin-2 receptors. A novel model for activation of human peripheral blood mononuclear cells by interleukin 2., PMID:7759316
Humanized antibody directed to the IL-2 receptor beta-chain prolongs primate cardiac allograft survival., PMID:7930631
Radioimmunotherapy of nude mice bearing a human interleukin 2 receptor alpha-expressing lymphoma utilizing the alpha-emitting radionuclide-conjugated monoclonal antibody 212Bi-anti-Tac., PMID:8044783
Differential expression of interleukin-2 receptor alpha and beta chains in relation to natural killer cell subsets and aerobic fitness., PMID:7822069
Differential expression of interleukin-2 receptors (alpha and beta chain) in mature lymphoid neoplasms., PMID:7514848
The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells., PMID:8197161
Cooperative interactions between the interleukin 2 receptor alpha and beta chains alter the interleukin 2-binding affinity of the receptor subunits., PMID:8159750
Angiocentric lymphoma with granulomatous panniculitis in the skin expressing natural killer cell and large granular T-cell phenotypes., PMID:7850074
Human melanoma cells express a functional interleukin-2 receptor., PMID:8344747
Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC., PMID:8335891
Alpha (p55) and beta (p75) chains of the interleukin-2 receptor are expressed by AML blasts., PMID:8445947
Functional expression of interleukin 2 receptor in a human factor-dependent megakaryoblastic leukemia cell line: evidence that granulocyte-macrophage colony-stimulating factor inhibits interleukin 2 binding to its receptor., PMID:8425202
Histological analysis of IL-2 induced regression of murine solid SL2-tumors., PMID:8104452
Mik-beta 1(Fv)-PE40, a recombinant immunotoxin cytotoxic toward cells bearing the beta-chain of the IL-2 receptor., PMID:1401913
Reconstitution of the intermediate-affinity interleukin-2 receptor by cell fusion., PMID:1489730
Tumor recognition and lytic competence of IL-2-activated lymphocytes: regulation of both antibody-independent and -dependent cellular cytotoxicity via P75 IL-2 receptor., PMID:1420599
Expression of the interleukin-2 receptor on human fibroblasts and its biological significance., PMID:1379826
Interleukin-2 induces tumor necrosis factor-alpha production by activated human T cells via a cyclosporin-sensitive pathway., PMID:1353987
Diagnostic and clinical importance of interleukin-2 receptor alpha chain expression on non-T-cell acute leukaemia cells., PMID:1581211
Expression of IL-2 receptor/p75 on lymphocytes from patients with rubella., PMID:1580147
Regulation of IL-2 beta receptor expression and beta-chain mRNA by human thymocytes., PMID:1733630
Interleukin 5 up-regulates high-affinity interleukin 2 receptor expression by human resting peripheral T cells: a comparison with the effect of interleukin 4 on B cells., PMID:1790306
The effects of IL-1, IL-2, and tumor necrosis factor on polymorphonuclear leukocyte Fc gamma receptor-mediated phagocytosis. IL-2 down-regulates the effect of tumor necrosis factor., PMID:1890305
Functional p75 interleukin-2 receptor expression on the fresh blast cells in childhood acute lymphoblastic leukemia with natural killer cell properties., PMID:2012073
Signal transduction through the human IL-2 receptor beta-chain expressed in IL-6-dependent mouse B cell hybridoma., PMID:2049334
Preferential expression of IL-2 receptor subunits on memory populations within CD4+ and CD8+ T cells., PMID:1900055
Flow cytometric analysis of expression of interleukin-2 receptor beta chain (p70-75) on various leukemic cells., PMID:2383656
Reconstitution of a functional IL-2 receptor by the beta-chain cDNA. A newly acquired receptor transduces negative signal., PMID:2592767
Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies., PMID:2467293
For research use only. Not for human or drug use.
