Catalog No.
PHC06201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ANXA1 (Met1-Asn346).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
LPC1,Calpactin-2,Lipocortin I,ANX1,ANXA1,Phospholipase A2 inhibitory protein,Chromobindin-9,Annexin I,Annexin A1,p35,Calpactin II,Annexin-1
Purification
Purified by antigen affinity column.
Accession
P04083
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Eosinophils-Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF-β Pathway Mediated by Anxa1 Binding., PMID:40125663
Monoclonal Antibodies Targeting Porcine Macrophages Are Able to Inhibit the Cell Entry of Macrophage-Tropic Viruses (PRRSV and ASFV)., PMID:40006922
Adaptive Proteomic Changes in Protein Metabolism and Mitochondrial Alterations Associated with Resistance to Trastuzumab and Pertuzumab Therapy in HER2-Positive Breast Cancer., PMID:40004024
Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation., PMID:39923118
Investigation of circulating natural autoantibodies against ANXA1 and MYC as potential biomarkers in hepatocellular carcinoma., PMID:39824386
Suppression of renal crystal formation, inflammation, and fibrosis by blocking oncostatin M receptor β signaling., PMID:39572752
Laboratory measurement of autoantibodies to Annexin A1: Review and measurements in health and COVID-19., PMID:39520946
Loss of Annexin A1 in macrophages restrains efferocytosis and remodels immune microenvironment in pancreatic cancer by activating the cGAS/STING pathway., PMID:39237260
A therapeutic antibody targeting annexin-A1 inhibits cancer cell growth in vitro and in vivo., PMID:38200229
Deciphering the immune landscape of head and neck squamous cell carcinoma: A single-cell transcriptomic analysis of regulatory T cell responses to PD-1 blockade therapy., PMID:38096229
Mechanisms Limiting Renal Tissue Protection and Repair in Glomerulonephritis., PMID:37176025
ANXA1-derived peptide for targeting PD-L1 degradation inhibits tumor immune evasion in multiple cancers., PMID:37001908
Contribution of plasma, placental, inflammatory and pro-resolving mediators in labor induction., PMID:35390665
Characterization of Tumor-Associated Macrophages and the Immune Microenvironment in Limited-Stage Neuroendocrine-High and -Low Small Cell Lung Cancer., PMID:34200100
Proteome profiling reveals the efficacy and targets of sophocarpine against asthma., PMID:33857804
HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1., PMID:33808657
2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression., PMID:33796096
The ABCA1-efferocytosis axis: A new strategy to protect against atherosclerosis., PMID:33741356
Serum IgG2 antibody multi-composition in systemic lupus erythematosus and in lupus nephritis (Part 2): prospective study., PMID:33351137
Immunoproteomics approach revealed elevated autoantibody levels against ANXA1 in early stage gallbladder carcinoma., PMID:33261560
Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease., PMID:33159915
Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis., PMID:32938681
Monoclonal antibody therapy that targets phospholipid-binding protein delays lupus activity in MRL/lpr mice., PMID:32533866
Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models., PMID:32497150
Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance., PMID:31142442
Lack of Endogenous Annexin A1 Increases Mast Cell Activation and Exacerbates Experimental Atopic Dermatitis., PMID:30650525
Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation., PMID:30459351
Resolution of inflammation in neuromyelitis optica spectrum disorders., PMID:30300851
Increased Levels of Circulating Anti-ANXA1 IgG Antibody in Patients with Non-Small Cell Lung Cancer., PMID:29945332
[Expression of annexin A1 in peripheral blood cells of Naïve rheumatoid arthritis patients and its influencing factors]., PMID:28693070
Circulating Antibodies to Linear Peptide Antigens Derived from ANXA1 and FOXP3 in Lung Cancer., PMID:28551657
Characterization of Ostertagia ostertagi annexin-like proteins at different developmental stages., PMID:28378195
Annexin A1 promotes timely resolution of inflammation in murine gout., PMID:27995621
Identification of specific biomarkers for gastric adenocarcinoma by ITRAQ proteomic approach., PMID:27941907
Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4+ T Cells., PMID:27833268
Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance., PMID:27172896
A panel of autoantibodies as potential early diagnostic serum biomarkers in patients with breast cancer., PMID:27778118
Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis., PMID:27343762
Proteomic analysis of fine-needle aspiration in differential diagnosis of thyroid nodules., PMID:27172385
Resolvin D1 Alleviates the Lung Ischemia Reperfusion Injury via Complement, Immunoglobulin, TLR4, and Inflammatory Factors in Rats., PMID:27145782
A novel anti-inflammatory mechanism of high density lipoprotein through up-regulating annexin A1 in vascular endothelial cells., PMID:27012521
[Changes in the expression of three markers in T lymphocytes of peripheral blood and immunoregulatory mechanisms of burned mice with sepsis at early stage]., PMID:26902275
The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil., PMID:26803520
A panel of autoantibodies as potential early diagnostic serum biomarkers in patients with cervical cancer., PMID:26738866
Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic., PMID:26407609
Integrative proteomic and gene expression analysis identify potential biomarkers for adjuvant trastuzumab resistance: analysis from the Fin-her phase III randomized trial., PMID:26358523
Activation of annexin A1 signalling in renal fibroblasts exerts antifibrotic effects., PMID:26332853
Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique., PMID:26287192
Membrane proteome analysis of glioblastoma cell invasion., PMID:25853691
Beneficial effect of annexin A1 in a model of experimental allergic conjunctivitis., PMID:25795053
For research use only. Not for human or drug use.
