Catalog No.
PHC05101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VTN (Glu126-Leu478).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
VN,VTN,Vitronectin,S-protein,Serum-spreading factor,V75
Purification
Purified by antigen affinity column.
Accession
P04004
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A Novel Recombinant Vitronectin Variant Supports the Expansion and Differentiation of Pluripotent Stem Cells in Defined Animal-Free Workflows., PMID:39329750
Targeting tumor cell-to-macrophage communication by blocking Vtn-C1qbp interaction inhibits tumor progression via enhancing macrophage phagocytosis., PMID:38773982
Macrophage promotes fibroblast activation and kidney fibrosis by assembling a vitronectin-enriched microenvironment., PMID:37441594
Inflammasome Coordinates Senescent Chronic Wound Induced by Thalassophryne nattereri Venom., PMID:37176162
Early immunologic response to mRNA COVID-19 vaccine in patients receiving biologics and/or immunomodulators., PMID:34545370
A replication-competent adenovirus-vectored influenza vaccine induces durable systemic and mucosal immunity., PMID:33529172
Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology., PMID:33259607
Vitronectin is Involved in the Morphological Transition of Neurites in Retinoic Acid-Induced Neurogenesis of Neuroblastoma Cell Line Neuro2a., PMID:30937689
Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF., PMID:30408465
The Streptococcus agalactiae cell wall-anchored protein PbsP mediates adhesion to and invasion of epithelial cells by exploiting the host vitronectin/αv integrin axis., PMID:30030946
Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin-FAK and uPAR signaling., PMID:29222114
The nuclear receptor NOR-1/NR4A3 regulates the multifunctional glycoprotein vitronectin in human vascular smooth muscle cells., PMID:28666984
Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R., PMID:28010135
Notch increased vitronection adhesion protects myeloma cells from drug induced apoptosis., PMID:26494298
Oral priming with replicating adenovirus serotype 4 followed by subunit H5N1 vaccine boost promotes antibody affinity maturation and expands H5N1 cross-clade neutralization., PMID:25629161
The hierarchical process of differentiation of long-lived antibody-secreting cells is dependent on integrated signals derived from antigen and IL-17A., PMID:24058589
Vitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages., PMID:23345331
Pre-clinical evaluation of a replication-competent recombinant adenovirus serotype 4 vaccine expressing influenza H5 hemagglutinin., PMID:22363572
Vitronectin dictates intraglomerular fibrinolysis in immune-mediated glomerulonephritis., PMID:21764994
The nuclear localization signal sequence of porcine circovirus type 2 ORF2 enhances intracellular delivery of plasmid DNA., PMID:21305328
Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at maternal-conceptus interface and uterine wall during ovine pregnancy., PMID:19060096
An enzyme-linked immunosorbent assay for lipovitellin quantification in copepods: a screening tool for endocrine toxicity., PMID:14982375
Contortrostatin, a homodimeric snake venom disintegrin, is a potent inhibitor of osteoclast attachment., PMID:9525341
Differential expression of a truncated form of the urokinase-type plasminogen-activator receptor in normal and tumor thyroid cells., PMID:9515821
Prevalence of rotavirus antibodies in a non-human primate colony., PMID:12160439
Chronic membrane depolarization regulates the level of the guanine nucleotide binding protein Go alpha in cultured neuronal cells., PMID:3131483
For research use only. Not for human or drug use.
