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Research Grade Anti-HCV NS1/Envelope glycoprotein E2 (MBL-HCV1)

Catalog #:   DVV08601 Specific References (94) DATASHEET
Host species: Human
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DVV08601

Expression system

Mammalian Cells

Species reactivity

Hepatitis C Virus (HCV)

Host species

Human

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27958

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

MBL-HCV1, MBL HCV1

Clone ID

MBL-HCV1

Data Image
  • SDS-PAGE
    SDS PAGE for HCV NS1/Envelope glycoprotein E2 Antibody
References

HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development. PMID: 34069740

Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease. PMID: 1314578

Expression of HCV E2/NS1 protein as a fusion protein with maltose binding protein: detection of anti-E2/NS1 antibody in chronic liver disease. PMID: 7686121

Roles of secretory glycoproteins in particle formation of Flaviviridae viruses. PMID: 31342548

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. PMID: 1846505

[Hepatitis C]. PMID: 8345654

Hepatitis C and liver transplantation. PMID: 8527717

Degree and distribution of variability in the 5' untranslated, E1, E2/NS1 and NS5 regions of the hepatitis C virus (HCV). PMID: 9751009

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins. PMID: 28991176

Antibody response to E2/NS1 hepatitis C virus protein in patients with acute hepatitis C. PMID: 9076628

Viral Interference Between Dengue Virus and Hepatitis C Virus Infections. PMID: 32875000

[Hepatitis C immunology]. PMID: 10614142

Secretion and purification of hepatitis C virus NS1 glycoprotein produced by recombinant baculovirus-infected insect cells. PMID: 7686870

Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients. PMID: 8959633

Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver. PMID: 9159034

Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae. PMID: 28644867

Expression and purification of E2/NS1 protein of hepatitis C virus and detection of anti-E2/NS1 antibodies in chronic liver disease patients. PMID: 12595764

Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases. PMID: 1379627

Syntheses of immunodominant peptide regions of hepatitis C viral pathogens using PS-BDODMA resin: a single peptide derived from the conserved domain (E2/NS1) was highly effective in detecting anti-HCV antibodies. PMID: 11168897

[Evolution of hepatitis C virus (HCV) viremia and adaptation of HCV in persistent infection in patients with acute hepatitis]. PMID: 7521430

[Significance of polypeptide antigen of HCVE2/NS1 relative conservation region in detection of anti-HCV]. PMID: 12759957

Natural history of hepatitis C. PMID: 7529217

Epidemiological studies on hepatitis C virus infection: detection, prevalence, exposure and prevention. PMID: 7814243

Development and Evaluation of a Universal and Supersensitive NS1-Based Luciferase Immunosorbent Assay to Detect Zika Virus-Specific IgG. PMID: 31552611

Structure, genomic organization, replication and variability of hepatitis C virus. PMID: 8918741

Sequence uniqueness and sequence variability as modulating factors of human anti-HCV humoral immune response. PMID: 18256830

[Fundamental studies of hepatitis C virus: a review]. PMID: 1331574

Genomic typing of hepatitis C viruses from Korean patients: implications of genome variation in the E2/NS1 region. PMID: 8240354

Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein. PMID: 1655961

Expression of structural proteins of hepatitis C virus (HCV) in mammalian cells. PMID: 18726270

Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1. PMID: 21715376

[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy in relation to clinical course]. PMID: 7521410

Use of a novel hepatitis C virus (HCV) major-epitope chimeric polypeptide for diagnosis of HCV infection. PMID: 10203493

Hepatitis C transmission between spouses. PMID: 8985816

[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy]. PMID: 7563902

[Innate immune responses against viral infection and its suppression by viral proteins]. PMID: 23449408

Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants. PMID: 7689636

Variability of the E2/NS1 region of Swedish hepatitis C virus strains and its correlation to genotypes. PMID: 7939424

A novel antigen detection immunoassay for field diagnosis of hepatitis C virus infection. PMID: 14677657

Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells. PMID: 8212557

Comparison between homologies of E2/NS1 gene from genotype III Chinese isolates of hepatitis C virus and that from reported isolates. PMID: 11155671

Confirmation of hepatitis C infection: a comparison of five immunoblot assays. PMID: 7519796

[Molecular genotypes of hepatitis C virus and their divergence times]. PMID: 8385234

Low-level hepatitis C viremia and humoral immune response to NS4 in chronic hepatitis B virus-hepatitis C virus coinfection. PMID: 15513365

Hepatitis C virus-related proteins in kidney tissue from hepatitis C virus-infected patients with cryoglobulinemic membranoproliferative glomerulonephritis. PMID: 9141444

Hepatitis C virus transmission in a pediatric oncology ward: analysis of an outbreak and review of the literature. PMID: 11310819

Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study. PMID: 23356386

Prevention of allograft HCV recurrence with peri-transplant human monoclonal antibody MBL-HCV1 combined with a single oral direct-acting antiviral: A proof-of-concept study. PMID: 28127942

High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody. PMID: 24956119

HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development., PMID:34069740

Mutations in different regions of the genome of hepatitis C virus genotype 1b and association with response to interferon therapy., PMID:23064792

[Cloning and sequencing of cDNA of E2/NS1 gene of hepatitis C virus]., PMID:15617335

[Expression of hepatitis C viral structure protein by recombinant vaccinia virus]., PMID:15617243

Sequential changes of hepatitis C virus antibody profiles during treatment of chronic hepatitis C of genotype 1b: pretreatment antibody response to E2/NS1 correlated sustained response., PMID:15188075

[Cloning and sequence analysis of E1, E2/NS1 region of genotype 2a hepatitis C virus genome]., PMID:12870013

[Significance of polypeptide antigen of HCVE2/NS1 relative conservation region in detection of anti-HCV]., PMID:12759957

Expression and purification of E2/NS1 protein of hepatitis C virus and detection of anti-E2/NS1 antibodies in chronic liver disease patients., PMID:12595764

Identification of human hepatocyte protein(s), which binds specifically to the recombinant envelope-2/non-structural-1 protein of hepatitis C virus., PMID:12191777

Antibody response to E2 glycoprotein induced in mice by immunization with plasmid DNA containing sequence derived from a Chinese genotype III/2a isolate of hepatitis C virus., PMID:11593587

Molecular design and immunogenicity studies of multiple antigenic peptide corresponding to envelope glycoprotein hypervariable region 1 of hepatitis C virus., PMID:11503045

Predominance of antibodies to hepatitis C virus envelope proteins in various disease statuses of hepatitis C., PMID:11394572

[Expression of glycoprotein hepatitis C virus in mammalian cell and application of purified protein for detection of antibody against E2 in hepatitis C patients]., PMID:10715790

[Sequence diversity of genotype II/1b hepatitis C virus (HCV) HVR1 of 46 patients in Beijing areas]., PMID:10488415

Degree and distribution of variability in the 5' untranslated, E1, E2/NS1 and NS5 regions of the hepatitis C virus (HCV)., PMID:9751009

Differences in hepatitis C virus quasispecies composition between liver, peripheral blood mononuclear cells and plasma., PMID:9225024

Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver., PMID:9159034

Antibody response to E2/NS1 hepatitis C virus protein in patients with acute hepatitis C., PMID:9076628

Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients., PMID:8959633

Comparison of hypervariable regions (HVR1 and HVR2) in positive- and negative-stranded hepatitis C virus RNA in cancerous and non-cancerous liver tissue, peripheral blood mononuclear cells and serum from a patient with hepatocellular carcinoma., PMID:8760588

Discrepancy of hepatitis C virus genotypes as determined by phylogenetic analysis of partial NS5 and core sequences., PMID:8818959

Lack of correlation between different hepatitis C virus screening and confirmatory assays., PMID:8793841

Quantitative analysis of antibody to hepatitis C virus envelope 2 glycoprotein in patients with chronic hepatitis C virus infection., PMID:8621173

Hepatitis C in human immunodeficiency virus-coinfected patients: increased variability in the hypervariable envelope coding domain., PMID:8666318

Sequence variation of the hypervariable region in HCV carriers with normal ALT levels: a comparison with symptomatic carriers., PMID:9013492

Fraction-specific populations of the hypervariable region of the hepatitis C virus in a patient with cryoglobulinemia., PMID:7595420

Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses., PMID:7815542

Prevalence of hepatitis C virus sequence variants in South-East Asia., PMID:7844535

The serology of hepatitis C virus (HCV) infection: antibody crossreaction in the hypervariable region 1., PMID:7503672

Influence of antibodies to the hypervariable region of E2/NS1 glycoprotein on the selective replication of hepatitis C virus in chimpanzees., PMID:7941335

[Evolution of hepatitis C virus (HCV) viremia and adaptation of HCV in persistent infection in patients with acute hepatitis]., PMID:7521430

[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy in relation to clinical course]., PMID:7521410

Adaptation of hepatitis C virus for persistent infection in patients with acute hepatitis., PMID:7545924

Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells., PMID:8212557

Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants., PMID:7689636

Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection., PMID:8382721

[Hepatitis C]., PMID:8345654

Antigenic regions within the hepatitis C virus envelope 1 and non-structural proteins: identification of an IgG3-restricted recognition site with the envelope 1 protein., PMID:7680297

[Expression of hepatitis C virus genome]., PMID:7681882

Persistence of hepatitis B and hepatitis C viral genomes in primary liver cancers from HBsAg-negative patients: a study of a low-endemic area., PMID:8380790

Expression of HCV E2/NS1 protein as a fusion protein with maltose binding protein: detection of anti-E2/NS1 antibody in chronic liver disease., PMID:7686121

Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease., PMID:1314578

Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein., PMID:1655961

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins., PMID:1846505

Hepatitis C virus (HCV)-RNA in non-A, non-B chronic hepatitis in France. Nucleotide sequence of a French HCV isolate., PMID:1668329

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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Research Grade Anti-HCV NS1/Envelope glycoprotein E2 (MBL-HCV1) [DVV08601]
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