Catalog No.
VVV19901
Species reactivity
Dengue virus type 2 (DENV-2)
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Applications
ELISA, Neutralization
Target
E glycoprotein, Envelope protein E, EDIII
Concentration
2.43 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
W5RZ25,P18356
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0124
Note
For research use only. Not suitable for clinical or therapeutic use.
Infectious clone construction of dengue virus type 2, strain Jamaican 1409, and characterization of a conditional E6 mutation., PMID:16847122
Type- and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes., PMID:17881453
Monoclonal antibodies that bind to common epitopes on the dengue virus type 2 nonstructural-1 and envelope glycoproteins display weak neutralizing activity and differentiated responses to virulent strains: implications for pathogenesis and vaccines., PMID:18160621
Emergence of the Asian 1 genotype of dengue virus serotype 2 in viet nam: in vivo fitness advantage and lineage replacement in South-East Asia., PMID:20651932
Synthetic peptides containing B- and T-cell epitope of dengue virus-2 E domain III provoked B- and T-cell responses., PMID:21419774
Eliciting cross-neutralizing antibodies in mice challenged with a dengue virus envelope domain III expressed in Escherichia coli., PMID:22420529
Dengue virus neutralization and antibody-dependent enhancement activities of human monoclonal antibodies derived from dengue patients at acute phase of secondary infection., PMID:23545366
Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection., PMID:23785205
Dengue virus type 2: protein binding and active replication in human central nervous system cells., PMID:24302878
Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing., PMID:24335303
Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention., PMID:24550728
Low antibody titers 5 years after vaccination with the CYD-TDV dengue vaccine in both pre-immune and naïve vaccinees., PMID:26889737
In-vitro effect of human cathelicidin antimicrobial peptide LL-37 on dengue virus type 2., PMID:28400226
Pichia pastoris-Expressed Bivalent Virus-Like Particulate Vaccine Induces Domain III-Focused Bivalent Neutralizing Antibodies without Antibody-Dependent Enhancement in Vivo., PMID:29367852
Anti-inflammatory Compound Shows Therapeutic Safety and Efficacy against Flavivirus Infection., PMID:31636070
Zika virus envelope nanoparticle antibodies protect mice without risk of disease enhancement., PMID:32305868
Antiviral Activity of Compound L3 against Dengue and Zika Viruses In Vitro and In Vivo., PMID:32517029
Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo., PMID:33299049
Sulfated β-glucan from Agaricus subrufescens inhibits flavivirus infection and nonstructural protein 1-mediated pathogenesis., PMID:35533778
Quercetin attenuates viral infections by interacting with target proteins and linked genes in chemicobiological models., PMID:36119653
N-Butanol Extract of Glycyrrhizae Radix et Rhizoma Inhibits Dengue Virus through Targeting Envelope Protein., PMID:37259408
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane., PMID:37506573
Multi-epitope peptide vaccines targeting dengue virus serotype 2 created via immunoinformatic analysis., PMID:39085250
Darunavir inhibits dengue virus replication by targeting the hydrophobic pocket of the envelope protein., PMID:40024350