Catalog No.
FHD63010
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Endothelin receptor type B, EDNRB, ETRB, ET-BR, Endothelin receptor non-selective type, ET-B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P24530
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0780
Mechanistic Characterization of the Potency of THIOMAB Antibody-Drug Conjugates Targeting Staphylococcus aureus and ETbR-Expressing Tumor Cells Using Quantitative LC-MS/MS Analysis of Intracellular Drug Accumulation., PMID:40179311
Development of chromone-thiazolidine-2,4-dione Knoevenagel conjugates as apoptosis inducing agents., PMID:38909705
Analysis of the relationship between the expression of EBV-related antibodies and ET-1 axis in gastric cancer., PMID:36373306
Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma., PMID:31385109
Identification of An mtDNA Setpoint Associated with Highest Levels of CD44 Positivity and Chemoresistance in HGC-27 and MKN-45 Gastric Cancer Cell Lines., PMID:29845783
The expression of ETAR in liver cirrhosis and liver cancer., PMID:28812426
Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis., PMID:28606962
Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis., PMID:27478465
TNFα-induced airway smooth muscle cell proliferation depends on endothelin receptor signaling, GM-CSF and IL-6., PMID:27422754
Endothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor., PMID:24901342
Electrophoresis-enhanced detection of deoxyribonucleic acids on a membrane-based lateral flow strip using avian influenza H5 genetic sequence as the model., PMID:24603637
Validation of histological diagnostic methods for detecting endothelin B receptor expression., PMID:24549269
Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by ETAR-dependent JNK/AP-1 pathway., PMID:24486572
The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor., PMID:24473118
Connexin-43 hemichannels contribute to the propagation of μ-calpain-mediated neuronal death in a cortical ablation injury model., PMID:24383076
The endothelin A receptor mediates fibrocyte differentiation in chronic obstructive asthma. The involvement of connective tissue growth factor., PMID:23795584
Photothermal effects of multi-walled carbon nanotubes on the viability of BT-474 cancer cells., PMID:25427516
Binding of circulating autoantibodies in breast cancer to native and peroxynitrite-modified RNA., PMID:23303630
Generation and characterization of rendomab-B1, a monoclonal antibody displaying potent and specific antagonism of the human endothelin B receptor., PMID:23221682
Endothelin-1 cooperates with hypoxia to induce vascular-like structures through vascular endothelial growth factor-C, -D and -A in lymphatic endothelial cells., PMID:22552325
Endothelin-1 induces endoplasmic reticulum stress by activating the PLC-IP(3) pathway: implications for placental pathophysiology in preeclampsia., PMID:22503784
Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure., PMID:22287612
Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy., PMID:21797847
Electroporation-aided DNA immunization generates polyclonal antibodies against the native conformation of human endothelin B receptor., PMID:21688998
Endothelin-1 regulates rat bone sialoprotein gene transcription., PMID:20587945
Effect of MOG sensitization on somatosensory evoked potential in Lewis rats., PMID:19423134
Targeted therapies in breast cancer: established drugs and recent developments., PMID:18690883
Endothelin potentiates TRPV1 via ETA receptor-mediated activation of protein kinase C., PMID:18001466
Altered endothelin receptor subtypes in colorectal cancer., PMID:17700263
Imbalance between expression of endothelin receptors A and B in terminal liver cirrhosis due to hepatitis C viral infection: immunohistochemical study of autopsy cases., PMID:17565586
The role of the endothelin axis and microvessel density in bladder cancer - correlation with tumor angiogenesis and clinical prognosis., PMID:17549358
Effect of type-1 diabetes mellitus on the regulation of insulin and endothelin-1 receptors in rat hearts., PMID:17487263
Expression of the Endothelin-axis in the different histologic subtypes of renal cell carcinoma: a tissue microarray analysis., PMID:17203161
Endothelin B receptor in human glaucoma and experimentally induced optic nerve damage., PMID:16682595
Mechanisms underlying the dysfunction of melanocytes in vitiligo epidermis: role of SCF/KIT protein interactions and the downstream effector, MITF-M., PMID:15095274
Characterization and application of monoclonal antibodies against human endothelin B receptor expressed in insect cells., PMID:15055764
Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes., PMID:12756260
Endothelin B receptor-like immunoreactivity in podocytes of the rat kidney., PMID:12389663
ENOS, ET-1 and ETB-R immunoreactivities in the porcine mesometrial lymphatics during the estrous cycle., PMID:12219837
Design, production, and characterization of recombinant neocarzinostatin apoprotein in Escherichia coli., PMID:11983081
Enhanced expression of endothelin B receptor at protein and gene levels in human cirrhotic liver., PMID:11583963
Localization of endothelin-A and -B receptors during the postnatal development of rat cerebellum., PMID:11572084
Mechanosensitive transcription factors involved in endothelin B receptor expression., PMID:11457849
Enhanced expression of endothelin receptor subtypes in cirrhotic rat liver., PMID:11318980
Immunohistochemical localization of Galphaq, PLCbeta, Galphai1-2, PKA, and the endothelin B and extracellular Ca2+-sensing receptors during early amelogenesis., PMID:11145362
Role of endothelin-1 in neovascularization of ovarian carcinoma., PMID:11073813
Endothelin A and B receptors change their expression levels during development of human placental villi., PMID:10940204
Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific., PMID:10789830
Subtype-specific trafficking of endothelin receptors., PMID:10722707
Heteroduplex analysis of VDJ amplified segments from rearranged IgH genes for clonality assessments in B-cell non-Hodgkin's lymphoma. A comparison between different strategies., PMID:10477449
For research use only. Not for human or drug use.
