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Anti-Mouse CD45/PTPRC Antibody (SAA0570)

Catalog #:   FMC34010 Specific References (50) DATASHEET
Host species: Mouse
Isotype: VHH, mFc (IgG2a)
Applications: FCM
Accession: P06800
Overview

Catalog No.

FMC34010

Species reactivity

Mouse

Host species

Mouse

Isotype

VHH, mFc (IgG2a)

Clonality

Monoclonal

Conjugation

Unconjugated

Target

T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06800

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.09% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0570

Data Image
  • Flow-cytometry
    Flow-cytometry using anti-mouse CD45 antibody.Raw264.7 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-mouse CD45 antibody monoclonal antibody (Catalog # FMC34010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

HLA-DQ monomer-based enrichment of alloreactive CD4 T cells., PMID:40502077

Detectable SARS-CoV-2 specific immune responses in recovered unvaccinated individuals 250 days post wild type infection., PMID:40498720

Phenotypic Shifts in Macrophages Within Advanced Atherosclerotic Plaques in Humans., PMID:40496346

Single-cell proteomic analysis reveals Multiple Myeloma heterogeneity and the dynamics of the tumor immune microenvironment in precursor and advanced states., PMID:40482292

Site-Specific Immune and Stromal Architecture Drive Resistance to Trastuzumab Deruxtecan in HER2+ Metastatic Breast Cancer., PMID:40475468

The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557

FACS-Proteomics strategy toward extracellular vesicles single-phenotype characterization in biological fluids: exploring the role of leukocyte-derived EVs in multiple sclerosis., PMID:40394633

Alterations in CD8+CD45RA+CCR7- T cells as a potential biomarker for primary Sjögren's syndrome., PMID:40388849

Postnatal epigenetic differences in calves following transient fetal infection with bovine viral diarrhea virus., PMID:40316897

Multiplex immunophenotyping of human acute myeloid leukemia patients revealed single -cell heterogeneity with special attention on therapy sensitive and therapy resistant subpopulations., PMID:40313947

TRPV1 Defends the Healthy Murine Cornea against Staphylococcus aureus Adhesion Independently of Sensory Nerve Firing., PMID:40291673

Human Leukocyte Antigen Haplotypes Predisposing to Celiac Disease in Patients With Endometriosis., PMID:40260879

Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF., PMID:40258831

Evaluation of a cost-effective gating strategy for CD4+ T lymphocyte enumeration in HIV-infected individuals via flow cytometry., PMID:40253874

Morphological characteristics, extracellular vesicle structure and stem-like specificity of human follicular fluid cell subpopulation during osteodifferentiation., PMID:40253818

The bone marrow niche and hematopoietic system are distinctly remodeled by CD45-targeted astatine-211 radioimmunotherapy., PMID:40236126

Rare Subset of T Cells Form Heterotypic Clusters with Circulating Tumor Cells to Foster Cancer Metastasis., PMID:40236049

Antigen quantity is responsible for the discrepancy between phenotype and single antigen beads for the detection of human leukocyte antigen DQ antibody: Potential clinical implications., PMID:40228791

Recognition of different subsets of alloreactive T cells by activation-induced markers., PMID:40204006

Old hematopoietic stem cells retain competence to reconstitute a youthful B cell system that is highly responsive to protein-based vaccination., PMID:40188072

High dose acetaminophen re-polarizes CD11b+ cells in the tumor microenvironment towards an activated macrophage phenotype., PMID:40158231

Potential role of liver-resident CD3+ macrophages in HBV clearance in a mouse hepatitis B model., PMID:40143948

The influence of genetic factors on the clinical manifestations and response to systemic treatment of plaque psoriasis., PMID:40095058

4-Color Flow Cytometric Cytotoxicity Crossmatch Using Whole Blood Lysis., PMID:40090806

Combination therapy with Chicoric acid and PD-1/PD-L1 blockade improves the immunotherapy response in patient-derived ovarian cancer xenograft model., PMID:40087780

Leveraging T cell co-stimulation for enhanced therapeutic efficacy of trispecific antibodies targeting prostate cancer., PMID:40081942

In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity., PMID:40073090

Migration of Regulatory T Cells to the Peritumor Microenvironment of Experimental Glioblastoma., PMID:40071070

Phase 1 study of IMCnyeso, a T cell receptor bispecific ImmTAC targeting NY-ESO-1-expressing malignancies., PMID:40054461

Early CTLA4 increase in CD45+ blood cells: an emerging biomarker of atezolizumab-bevacizumab resistance and worse survival in advanced hepatocarcinoma., PMID:40048814

Analysis of Germinal Center Reaction in Competitive Bone Marrow Chimeric Rag2-/-γc-/-Mice., PMID:40029512

Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters., PMID:40027624

Nucleated Red Blood Cells Secrete Haptoglobin to Induce Immunosuppressive Function in Monocytes., PMID:40017804

Effect of chemoradiotherapy on the dynamics of circulating lymphocyte subsets in patients with non-metastatic nasopharyngeal carcinoma., PMID:40012553

Bioorthogonal Chemical Engineering of rAAV Capsid: Advancing Gene Therapy Targeting Using Proteins., PMID:39992873

Characterization of the Cellular Immune Response to Group B Streptococcal Vaginal Colonization., PMID:39975125

Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer., PMID:39969975

Allogeneic Chimeric Antigen Receptor T-Cell Products Cemacabtagene Ansegedleucel/ALLO-501 in Relapsed/Refractory Large B-Cell Lymphoma: Phase I Experience From the ALPHA2/ALPHA Clinical Studies., PMID:39946666

Immunohistochemical identification of immune cell subsets in formalin- and zinc-fixed, paraffin-embedded tissues from chicken and duck using commercial antibodies., PMID:39938274

Plasma leukocyte-derived extracellular vesicles are related to target vessel revascularization in off-pump coronary artery bypass grafting., PMID:39897018

Trends in the Perioperative Practices for Immunological Assessment and Immunosuppression Strategies for Patients Undergoing Intestinal Transplantation at American Transplant Centers., PMID:39890513

Combining magnetically isolated CD45 cells with serum maintains intact drug responsiveness for ELISpot analysis in clinical trials., PMID:39882960

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis., PMID:39877346

Clinico-Pathological Significance of Tumor Infiltrating Immune Cells in Oral Squamous Cell Carcinoma-Hope or Hype?, PMID:39865357

Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing., PMID:39830504

Dynamic analysis of intrahepatic T cells reveals a unique group of restorative Cxcr3+ tissue-resident CD4 T cells in acute liver injury., PMID:39828240

Targeting CD45 by gene-edited CAR T cells for leukemia eradication and hematopoietic stem cell transplantation preconditioning., PMID:39822756

Protocols for circulating neutrophil depletion in neonatal C57Bl/6 mice., PMID:39821323

GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth., PMID:39794935

Automatic Single-Cell Harvesting for Fetal Nucleated Red Blood Cell Isolation on a Self-Assemble Cell Array (SACA) Chip., PMID:39770268

Datasheet
$ 225
Product specifications
50 μg 225 100 μg 372

Contact Information

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For research use only. Not for human or drug use.

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Anti-Mouse CD45/PTPRC Antibody (SAA0570) [FMC34010]
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